5-hydroxytryptophan (5-HTP) - Supplement Profile According to this article I have all symptoms of seratonin deficiency. It recommends a different dosing protocol of 5htp based on the symptoms presenting - of course fixing all of the symptoms is important to me. Should I dose, say, 100mg in the morning, 200 mid, and 300mg at night? My appetite tends to get out of control at night anyway. Or just 300mg x3? Should I taper up the dose? I read this supplement I should treat with a bit of respect so I don’t want to mess too much too quickly with a chemical that is already affecting my life so much.