Skin Thread Over 40

I run KLOW from Opti daily and hoping the same thing. For better skin. As I've gotten into my 40s my skin is getting more loose so trying to get out in front of that!
 
IMO, the entire stack which one would need to improve/prevent photoaging is simply:

basic skincare routine;
- cleansing am and pm
- moisturizing after cleansing
- spf in am and even applied again in afternoon if you please
- topical retinoid daily (tazarotene or tretinoin 1% are fantastic choices)
*ramp up the frequency in which you use the topical retinoid of choice and also start with a weaker concentration and graduate to higher concentration*

drugs;
- low dose isotretinoin (5 mg/day or 10 mg MWF)
- GH (HRT replacement dose is entirely sufficient for skincare purposes)
- GHK-cu 2-3 mg/day (not as researched as the other interventions but i think its promising and sure wont hurt)

Theres other compounds that I think are worthy additions such as glutathione/antioxidants but the above more than covers your bases.

I personally use basic cerave foaming facial cleanser am and pm, (i let my face airdry after cleansing because towels just trap bacteria) basic cetaphil moisturizer, and la roche posay SPF. 10 mg isotret MWF, tretinoin 0.1% every night, 3 mg GHK-cu per day, 375 mg glutathione MWF, and im going to be starting GH in the near future.
 
Anyone inject Ghk-cu? Been doing the glow combo but switching to just ghk for a month to avoid receptor issues. The ghk (from peptide sciences) is super dark blue and has had pip at 2.5mg sub a. Much lighter blue with bpc and tb500 also and no pip. Any workarounds?

been looking into this as glow gave me bad site reaction and I suspect GHK-CU will too. make what you will of this one I found, Anela protocol:

Ratio 50mg GHK-CU to 10mg BPC; if you have 100mg GHK-CU it's 20mg BPC

✅ Bac needs to be 3mL per 50mg GHK-CU; if you have 100mg GHK-CU it's 6mL bac

✅ Syringe 8mm (5/16") — too long of a needle can go too deep on research subject (RS) and it becomes intramuscular. The half-life of GHK-CU is too short to make a difference. GHK-CU has a short plasma half-life. So please be careful with this. Intramuscular is a faster/rapid release. We do not want that. The slower release, the better.

✅ Are you using the Anela injection technique? Breaking up the 12 units (2mg GHK-CU) into 3 mini pins? This is a step most researchers miss and don't understand. Keep each pin under 5 units. This creates a slow release of GHK-CU, providing another layer for preventing the histamine response.

✅ After the 3 mini pins (4 units, 4 units, 4 units), add percussion massager for 3 to 5 minutes on high. This should not be done for any other peptides.

✅ Still not working? There are added measures for super responders. I am one of them.

✅ Any leftover ISRs (injection site reactions), always keep a vial of BPC on hand. BPC is a mast cell stabilizer. It will help anytime you have an ISR. Citation here on BPC and mast cell stabilization.

, .

➡️ I do not mention it often as it's a bit of a bigger step. You will need to obtain Epi/Lido (epinephrine/lidocaine). Do not ask where to get here, please. We can't do that. IYKYK.

Conduct this advanced workaround in your lab at your own risk.

Substitute 1mL of epi/lido for bac during reconstituting (do NOT use lido alone: the epi is necessary).

So you have: 50/10/10 or 50/10/10/10 with:

1mL epi/lido
2mL bac
2mg GHK-CU pin and 400mcg BPC
Break up into 3 mini pins
Percussion massager 5 minutes

Haven't tried it yet, lidocaine I can find but epinephrine with or without lidocaine requires a prescription.
 
been looking into this as glow gave me bad site reaction and I suspect GHK-CU will too. make what you will of this one I found, Anela protocol:



Haven't tried it yet, lidocaine I can find but epinephrine with or without lidocaine requires a prescription.
I had horrible reaction from KLOW blend myself. Wife, no problems. I believe some of us don't do well with what's happening between all of those peptides in the blend. I ordered KPV, GHK-CU, BPC157 and TB500, can run all independently just fine with no issues or reactions. I actually have noticed an improvement in my skin health/fine lines/healing from cuts since implementing the ghk-cu. On my second 100mg vial now.
 
I had horrible reaction from KLOW blend myself. Wife, no problems. I believe some of us don't do well with what's happening between all of those peptides in the blend. I ordered KPV, GHK-CU, BPC157 and TB500, can run all independently just fine with no issues or reactions. I actually have noticed an improvement in my skin health/fine lines/healing from cuts since implementing the ghk-cu. On my second 100mg vial now
I also suspect PIP is exacerbated when the GHK is in a blend. I experienced PIP with pinning GLOW for the first few days then haven’t experienced anything since - with the blend or with GHK solo
 
I had horrible reaction from KLOW blend myself. Wife, no problems. I believe some of us don't do well with what's happening between all of those peptides in the blend. I ordered KPV, GHK-CU, BPC157 and TB500, can run all independently just fine with no issues or reactions. I actually have noticed an improvement in my skin health/fine lines/healing from cuts since implementing the ghk-cu. On my second 100mg vial now.
might order some and try ghk-cu solo, I did find epinephrine in one of my expired kids epipen. Interestingly there is actually 5 doses in a single dose epipen, never knew that. Would come in handy in an emergency. Our health dept here is so far up itself that if you ask for extra pens beyond the two allowed for a kid, it's denied. Doctors have to call for permission to even write a script for a pen. Bureaucracy gone mad here.

There's a video on youtube on how to dismantle the pen and get the epinephrine cartridge. The extra doses keep stability and minimise degradation for years past expiry.

If solo still gives a bad site reaction Ill give the lido/epi a try.
 
might order some and try ghk-cu solo, I did find epinephrine in one of my expired kids epipen. Interestingly there is actually 5 doses in a single dose epipen, never knew that. Would come in handy in an emergency. Our health dept here is so far up itself that if you ask for extra pens beyond the two allowed for a kid, it's denied. Doctors have to call for permission to even write a script for a pen. Bureaucracy gone mad here.

There's a video on youtube on how to dismantle the pen and get the epinephrine cartridge. The extra doses keep stability and minimise degradation for years past expiry.

If solo still gives a bad site reaction Ill give the lido/epi a try.
Sad that they design it to not be fully utilized, really sums up healthcare/big pharma these days! Didn't realize you could dismantle them and still get the meds out. Unfortunately I feel the same way in regards to health care and being able to acquire things we should be able to have on hand, damn near have to offer to sell a kidney. Hopefully you have better luck with just the ghk-cu on it's own like I did man!
 
Sad that they design it to not be fully utilized, really sums up healthcare/big pharma these days! Didn't realize you could dismantle them and still get the meds out. Unfortunately I feel the same way in regards to health care and being able to acquire things we should be able to have on hand, damn near have to offer to sell a kidney. Hopefully you have better luck with just the ghk-cu on it's own like I did man!
turns out I did have a ghk-cu kit on hand, buried in the back of the fridge. completely forgot about it.

no issues with 1mg injection. will keep it to 1mg/site
 
I am getting a lot of compliments for looks (since i lost weight especially) from ladies at 47. a lot of good advice here like ghk-cu. I highly recommend 10g gelatin powder + collagen +acerola cherry powder(for the natural vit C) daily/post workout. did wonders do hair/skin/nails. can't go wrong with HGH but you need the elements. also, ditch all PUFA's from diet. important. sugar is fine.
 
I'm not over 40, but into skincare and I'm trying to age as slow as possible while doing steroids.

I'm using since a couple of months topical estrogen on my face and it definitely helped. I have more volume and no more dark circles under my eyes. I used the following protocol from reddit and upped the dose to twice per day (morning and evening)


My E2 came back not elevated at all, while using topcial estrogen twice per day on my face. I did even put it on my face in the morning before going to the lab for getting my blood tests done.

I can say that it's at least as effective as topical tretinoin (I'm using it daily since a couple of years).


In the next days my KLOW Blend should arrive, looking forward to it.

Any experience with steroids that lead to better skin?
 
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