I mean effects from the primo. How many weeks in are you? Just 200mg a week? I ordered the 150mg/ml to avoid any risk of pip.You mean in my left quad? I was alternating between the two for a few months when the right swole up. The left doesn’t seem impacted. I’ve even increased my dose and the left is feeling no pain. Maybe I just hit the wrong spot. I ordered some Primo 100 to see if that makes a difference.