Sterilizing Powders

[Mr. Magnificent]

Does anyone know if there is a cheap and practical way of sterilizing powders without reconstituting them first?

Microwave? Oven bake?

 

[Holidaypay]

Im new on here there will be alot smarter people to answer soon but from what I gathered there is no reason to sterilize powders cause filtering the oil will clean them

 

[Mr. Magnificent]

Im new on here there will be alot smarter people to answer soon but from what I gathered there is no reason to sterilize powders cause filtering the oil will clean them

Thats the point, I'm asking if there is a way to sterilize them before mixing them with the liquid. Can't filter powder through a whatman...

How can one make it like this without spending a million bucks on a machine?:

 

[ickyrica]

I think that's a whole different level of production man. Not sure but I don't think it's going to be cost effective in the least for some reason. Hope you get better news from someone that actually knows what they're talking about!!

 

[bonacris]

Why would you need to do this

 

[Taurus33]

So you want to reconstitute the medication, for every dose? I work at a hospital and technically medications that you re constitute in a liquid base are used all at once. So you would need a vial for every injection. What would you be doing this with just curious?

 

[master.on]

Does anyone know if there is a cheap and practical way of sterilizing powders without reconstituting them first?

Microwave? Oven bake?

1 You can dissolve them in alcohol
preferably Mthanol although Ethanol will also work

2 Sterile filter them
you can use a 0.10 um filter instead of 0.22 as alcohol is thinner than oil
maybe even down to 0.05 um

3 Distill (evaporate) the alcohol
You'll want to condense the boiled alcohol both
- for safety as alcohol is flammable, thus little or no flammable alcohol vapors
- for reduced expense as gear is much less soluble in alcohol
i.e. Test E is only soluble to 17.3 mg/mL in alcohol as compared to 300+ in oil

You'll need a condenser
Condenser (laboratory) - Wikipedia
and some other equipment like this
https://upload.wikimedia.org/wikipedia/commons/9/9c/Simple_distillation_apparatus.svg

As you can see there's a water bath
and the boiling flask (2) is fixed above (by some clamps or something not depicted in the image ) as to be ABOVE the water bath (14) recipient, as to avoid hot spots.

4 Place a big fan

blowing the few remaining vapours thru an open window.

5 Methanol boils at only 148 F (67 C)
So, for safety you can use a remote water heater as long as it gets to the desired temp.
Being remote you avoid an open flame near the (few) flammable vapours.

6 You can also use an explosion proof electric heater
Where the hot electric filament is embedded in a thick material an not to be exposed to flammable vapors
Many of these are submerged in the water bath, water ain't flammable you know
http://www.ebay.com/itm/2-NPT-120V-1KW-Immersion-Heater-Appleton-DER-1-Explosion-Proof-Junction-Box-/391685407636?hash=item5b32450394:g:zccAAOSwjDZYhpmV

7 Evaporate it all and pour the powder in vials
using a DIY glovebox
Glovebox - Wikipedia
or in improvised clean room
DIY Cleanroom
DIY cleanroom on a budget | Make:

Don't be scared
distilling ain't that dangerous if done properly
after all beer and liquor (and moonshiners LOL) distill flammable Ethyl alcohol every day, with makeshift equipment and you seldom hear of a fire.