Still learning, my impression.

[ASaxon]

Im still doing furious research on my situation. Im now slanting my assessment of my condition toward Obesity as being at least a partial cause of my hypogonadism. Heres the current impression and plan of attack for my situation:

My impression:
1) My two hydroceles and the resulting operations caused partial damage to my Testosterone production (especially the last one which started about seven years ago.).
2) My depression and symptoms lead to my weight gain about 10 years ago.
3) My weight gain caused my serum leptin levels to increase.

• Yet to be confirmed with labs and not usually tested for by doctors but expected with morbid obesity.

4) High Leptin has shown to cause and perpetuate obesity and may be a factor in lowering Testosterone and causing hypogonadism since it appears that leptin has an effect on hypothalamus and Pituitary function..
5) My symptoms are caused by hypogonadism.

My plan of attack is:
1) Go on TRT and relieve my symptoms.
2) If symptoms abate then hopefully I can finally loose weight successfully.
3) Carefully monitor blood work as I loose weight and scale back TRT as may be indicated.
4) Hopefully when I loose weight my baseline T without TRT will be sufficient
5) If my T is still low even after loosing weight then I guess Ill get use to TRT because Ill probably be on it for the rest of my life.

Whatcha think?

 

[pmgamer18]

Good pain and is just what I am and have been doing. I topped out at 335 lbs. But this was coused from being on AD drugs manly Remeron. I was told 21 yrs. ago after a lot of testing that they can't find anything wrong with me. So it must be that I am depressed. I went though this shit for 5 yrs. on every kind of AD Drug on the market. When Prozac come out they put me on it and it slowed down my voiding and I got a bad bladder infection. I had to see a Uro this Dr. asked me why I was on all of this AD meds. I told him my story and he told me he feels I have low T and am not suffering from Depression. I had to go into RE-Hab for 30 days to get off the AD drugs. I went though hell the first 2 weeks. When I first got sick I had bad fatigue so bad I could not get to work. This came on me slow and I fought it for as long as I could then I could not fight anymore and ended up on my ass. I have never felt 100% going on TRT but was able to go back to work. I retired at the age of 55 and now I am 61 and thinking about going back to work that is how good I feel thanks to Dr. John's postings on his way of treating Low T and his Hcg treatment. I am down to 272 lbs. now and walking everyday for one hour. I do Weight Watchers program and in the last 16 weeks am down 32 lbs. I am working out 3 times a week for 2 hrs. I can't tell you how good I feel and it was a dam long time coming. I wish you all the luck in the world and hope you get there I did.
Phil

 

[SWALE]

Estrogen production is enhanced by adipose tissue. Besides exerting its own effects, it also inhibits T production. It becomes a vicious cycle.

 

[ASaxon]

Question about E2 and Total Estrogen

Can someone have a normal E2 but an elevated Total Estrogen? If so what would be the effects physiologically?

 

[Random987]

(1)Yes. (2) Don't know

This is a very interesting question that has not really been determined or fully explored. I know that our good ol' doc has been looking at all of the various type of E and treatment/monitoring of same. I have normal E2, but high Total E. So, I am interested in the question as well.

Can someone have a normal E2 but an elevated Total Estrogen? If so what would be the effects physiologically?