STOCK UP: Don't say you weren't warned! (US)

[Kiyosh1]

IDK my raws are coming in even faster than before now lol

I have this problem with mine and can't get it as usual, sosadge

 

[Ghoul]

IMO, it's time to stock up on peptides.

If you're really serious, get a small cryofreezer so they'll have an effectively unlimited shelf life.

I was hoping peptides, as they fall through a legal loophole (except HGH), would be spared from the imminent de minimus crackdown. But the mountain of money on the line and end of legal compounded alternatives means big pharma has a new target to focus on, and non-GLP peptides will almost certainly be collateral damage.

These organizations have a nearly unlimited war chest of cash, and significant political influence already. The fact their interests align with what's already in motion makes it a near certainty in my opinion.

Thread 'Compounded Tirz has been vanquished. UGL likely next. Stock up.'

Friday at 8:16 AM

The following is my opinion as to what's just ahead of us in the UGL based drug landscape. It's based on my close observation of the political and business movements likely to affect this market. As with every opinion, feel free to take or discard my advice as you see fit.

https://apnews.com/article/obesity-drugs-zepbound-shortage-fda-13d18b0e3e74a7f7355521bf8e38cb5b

Eli Lily has finally succeeded in putting a stake in the heart of compounded copies of their $1000/mo drug. With the amount of money on the line, expect them to turn their attention to Chinese knockoffs.

While Tirz...

• Ghoul
• Replies: 6
• Forum: Weight Loss Drugs

• 

 

[Nunya]

IMO, it's time to stock up on peptides.

If you're really serious, get a small cryofreezer so they'll have an effectively unlimited shelf life.

I was hoping peptides, as they fall through a legal loophole (except HGH), would be spared from the imminent de minimus crackdown. But the mountain of money on the line and end of legal compounded alternatives means big pharma has a new target to focus on, and non-GLP peptides will almost certainly be collateral damage.

These organizations have a nearly unlimited war chest of cash, and significant political influence already. The fact their interests align with what's already in motion makes it a near certainty in my opinion.

Thread 'Compounded Tirz has been vanquished. UGL likely next. Stock up.'

Friday at 8:16 AM

The following is my opinion as to what's just ahead of us in the UGL based drug landscape. It's based on my close observation of the political and business movements likely to affect this market. As with every opinion, feel free to take or discard my advice as you see fit.

https://apnews.com/article/obesity-drugs-zepbound-shortage-fda-13d18b0e3e74a7f7355521bf8e38cb5b

Eli Lily has finally succeeded in putting a stake in the heart of compounded copies of their $1000/mo drug. With the amount of money on the line, expect them to turn their attention to Chinese knockoffs.

While Tirz...

• Ghoul
• Replies: 6
• Forum: Weight Loss Drugs

• 

Did you end up getting one of those small freezers? Been eyeballing them because why not

 

[Zebedee]

It’s been a week since I asked this of @Ghoul & no reply from him, despite his having posted again in this thread. I think it’s safe to assume he has no evidence & every one of his many posts on the topic was just baseless speculation & scaremongering.

17 weeks tomorrow ….

 

[Ghoul]

Did you end up getting one of those small freezers? Been eyeballing them because why not

Yeah I bought a this model of Stirling used on eBay, There are plenty for sale, When they decommission ambulances they don't transfer equipment to the new ones so many of these freezers become available. I paid $900, a few scratches but it's built as well as you'd expect a portable cooler that sells new for $8000 would be.

I love it. It's light, takes up very little space, once it reaches temp it's very quiet, and the insulation is outstanding so electric use is minimal (it can run directly off 12v as well as 120v AC). Temp is spot on at -122f .

I took up the empty space with solid freezer packs.

 

[Standfast]

Yeah I bought a this model of Stirling used on eBay, There are plenty for sale, When they decommission ambulances they don't transfer equipment to the new ones so many of these freezers become available. I paid $900, a few scratches but it's built as well as you'd expect a portable cooler that sells new for $8000 would be.

I love it. It's light, takes up very little space, once it reaches temp it's very quiet, and the insulation is outstanding so electric use is minimal (it can run directly off 12v as well as 120v AC). Temp is spot on at -122f .

I took up the empty space with solid freezer packs.

View attachment 308152View attachment 308151

What containment do you store your peptides in while in the freezer, what temperature and what process do you recommend when removing from for use. Like do you you place in refrigerator to allow a slow temperature aclamation.

Also thanks for sharing this units availability!

 

[Ghoul]

What containment do you store your peptides in while in the freezer, what temperature and what process do you recommend when removing from for use. Like do you you place in refrigerator to allow a slow temperature aclamation.

Also thanks for sharing this units availability!

Right now I'm using the same plastic cases with foam inserts I've always used, but this is far from ideal. At these temps, the plastic and foam become so brittle that even with gentle handling they're cracking and won't last long.

Besides the question of durability, the other factor I'm keeping in mind is exactly what you mentioned, The effect of temperature "shock" on the condition of stored peptides.

TLDR you want to freeze rapidly, -1c/minute, to prevent the formation of peptide damaging large crystals in whatever moisture content is present, and thaw slowly, to minimize mechanical stress on the proteins as they warm up and expand.

After digging into the methods used in labs handling proteins, this is best accomplished with alcohol filled cryo containers. I'm still looking for a model that will hold 3ml peptide vials. Most are designed for 2ml (or 5ml) vials. They may be compatible but so far I haven't been able to verify.

5100-1100 - Cryo Freezing Container

www.rpicorp.com

I only recently got the freezer, so I'm still working out best practices, but for now, two days before I need the vials, I transfer to the (regular) freezer for a couple of hours, then into the refrigerator.

 

[Standfast]

Right now I'm using the same plastic cases with foam inserts I've always used, but this is far from ideal. At these temps, the plastic and foam become so brittle that even with gentle handling they're cracking and won't last long.

Besides the question of durability, the other factor I'm keeping in mind is exactly what you mentioned, The effect of temperature "shock" on the condition of stored peptides.

TLDR you want to freeze rapidly, -1c/minute, to prevent the formation of peptide damaging large crystals in whatever moisture content is present, and thaw slowly, to minimize mechanical stress on the proteins as they warm up and expand.

This is best accomplished with alcohol filled cryo containers. I'm still looking for a model that will hold 3ml peptide vials. Most are designed for 2ml (or 5ml) vials. They may be compatible but so far I haven't been able to verify.

5100-1100 - Cryo Freezing Container

www.rpicorp.com

I only recently got the freezer, so I'm still working out best practices, but for now, two days before I need the vials, I transfer to the freezer for a couple of hours, then into the refrigerator.

Thanks for the feedback good man, would you share the ebay link as I've only been able to find that unit and a higher price.

 

[Ghoul]

Thanks for the feedback good man, would you share the ebay link as I've only been able to find that unit and a higher price.

Search for "Stirling Ultra", and regardless of asking price, make an initial $800 offer, and try to strike the best deal from there. I was prepared to go to $1500 if necessary, and whether I got unsually lucky or not I can't say since I only bought the one. But I'd expect you should be able to get close to my price.

The Chinese knockoffs are around $1200 (or less), so anything less than that for one of these is a bargain.

 

[Nunya]

Search for "Stirling Ultra", and regardless of asking price, make an initial $800 offer, and try to strike the best deal from there. I was prepared to go to $1500 if necessary, and whether I got unsually lucky or not I can't say since I only bought the one. But I'd expect you should be able to get close to my price.

The Chinese knockoffs are around $1200 (or less), so anything less than that for one of these is a bargain.

Thanks for the info, grabbed one earlier today