There is possible loss that happens when you suq q. The blood flow is so poor in that layer of tissue that, from what I've read, the enzyme that breaks the ester doesn't always get everything. The delivery is so slow that you may experience low serum levels. I tried sub q and it was awful! Lumps everywhere! Got an abcess and said fuck it. Felt like shit the whole time! Idk why anyone even bothers with sub q. I read a shit ton and thought it was gonna be my saving grace! And some accounts made it sound so good...but hey if it works for you that's great haha