RE: best TRT regimen
DavidZ,
Thanks (again) for info.
I have heard that also. Why would IM shots be more beneficial for joint pains than T delivered via a transdermal? One would think that T in the bloostream is T in the bloodstream, no matter whether it came via IM or via a transdermal.
Now I could see if the transdermal wasn't delivering as it was "supposed" to be. If, as an example, the 10 grams of AndroGel (two 5 gram packets) were actually only 8.3 grams (one packet being 3.9 grams and the other one 4.4 grams). And, in the example, the AndroGel wasn't really 1% strength (i.e., 83 mg of testosterone) but was an averaged out 0.73% strength (so 60.6mg of testosterone instead of the 83mg assumed). And instead of the 10% claimed that's getting through the skin barrier and into the bloodstream, that the averaged out level was 8% efficiency ratio. Guess what? The TRT patient is getting only 4.6 mg of testosterone from his "10 grams of AndroGel" rather than the 10 mg initially assumed.
If that represented an on-going "average", then the TRT patient switching over to an IM shot would see an huge difference, simply because the IM shot would be delivering an average 10mg testosterone daily (not exactly but close enough if getting weekly shots), no?
Is there some other factor that I'm missing?
Yes, point three I could see. That should be minimized if individual isn't applying over areas with higher BF though, correct? If shoulders / upper arms are more muscular and very little fat (and that's where application is taking place) then IM should have little advantage in the E2 area, no?
Ahh... still looking for the "best one" that applies for me! A shot once a week sounds good simply because it's less of a "hassle", but then one looks at the current recommendation of applying transdermals and doing HCG daily. Seems like recommendations go from simplier (the ancient 300 mg IM shot every three weeks) to more complex (transdermals and HCG daily)....
We need a Pharmaceutical to come through with a transdermal that would include not only varying levels of T but also of HCG and that would absorb at a very high efficency ratio and that would be completely absorbed within a couple minutes (no transference concerns) and because of its advanced transdermal efficiency levels would only be about a 1 gram packet!