T3 Replacement dose of 25 Mcg. Lab test

[Deleted member 59947]

If someone is truly hypo I start them there... is it more aggressive then most drs...definitely... will it cause extreme harm, not likely...
They have been having a low metabolism for a while to be partially hyper for a few weeks to a month while we figure out the optimal dose will likely help them shed some extra fat stored while being hypo...
My 2 cents

My exact reasoning. A girl at the gym has been having some unexplained weight gain for the past year, despite eating exactly the same and having the exact same energy expenditure.

I will start her on 25mcg T3 twice a day to see if that fixes it.
1) If she has hyperthyroid symptoms we will reduce the dose.
2) If there is no change, we will know thyroid is not her issue.

Done


PS: how to you dose T4 in conjunction with T3? I was thinking 50mcg T4 twice a week to prevent excess rT3.
Would you dose it daily?

 

[Canknucklehead]

My exact reasoning. A girl at the gym has been having some unexplained weight gain for the past year, despite eating exactly the same and having the exact same energy expenditure.

I will start her on 25mcg T3 twice a day to see if that fixes it.
1) If she has hyperthyroid symptoms we will reduce the dose.
2) If there is no change, we will know thyroid is not her issue.

Done


PS: how to you dose T4 in conjunction with T3? I was thinking 50mcg T4 twice a week to prevent excess rT3.
Would you dose it daily?

Dose t4 daily in AM. Do not consume calcium, iron, or coffee within 4 hours of taking the dose.

 

[Alphalfa]

Dose t4 daily in AM. Do not consume calcium, iron, or coffee within 4 hours of taking the dose.

That makes no sense at all, you are supposed to avoid caffeine with the T4 intake, but once it has been absorpted, after 30-60mins, it is totally ok to drink/eat whatever you need.

If it has been already absorpted, why would you avoid those things for that long? After all, once absorpted, there is no way you can do anything to avoid it, it is already absorpted...

 

[Canknucklehead]

T4 takes longer to absorb... t3 you should be safe after 60min... t4 wait at least 2-4 hours

Take SYNTHROID as a single dose, preferably on an empty stomach, one-half to one hour before breakfast. Products such as iron and calcium supplements and antacids can lower your body's ability to absorb levothyroxine, so SYNTHROID should be taken 4 hours before or after taking these products.

 

[Canknucklehead]

Levothyroxine and multivitamin with iron should not be taken orally at the same time. Products that contain iron may interfere with the absorption of levothyroxine and reduce its effectiveness. You should separate the dosing of these medications by at least 2 to 4 hours if possible.

 

[Deleted member 59947]

Dose t4 daily in AM. Do not consume calcium, iron, or coffee within 4 hours of taking the dose.

Thanks.
50mcg T4/day is enough?
Will 100mcg T4 cause too much rT3?

 

[Canknucklehead]

Thanks.
50mcg T4/day is enough?
Will 100mcg T4 cause too much rT3?

Start with 50mcg, possibly up to 75mcg. I wouldn’t raise it much higher then that considering her t3 dosage.

Personally for thyroid replacement therapy I usually recommend 50-100mcg t4 and 25-37.5mcg t3. Especially not higher in natural trainees.

Good luck and keep us posted on her results!

 

[lukiss96]

What are you talking about "experts"... Just a bunch of people that know nothing on this subject trying to give medical advice. The only way to go about it is to go to a endocrinologist or thyroidologist who at least know what they are talking about. There is a reason why mostly levothyroxine is used for hypothyroidism.

I take t4 (levothyroxine) and I need 125mcg/day this puts me at top level of ft4, ft3 ant TSH at 1, but not over and I feel good. This number is for me, not for any of you. Only blood work will tell you how much you need and it's not gonna happen right off the bat, most likely your dose will be adjusted for the next couple of months and maybe even a year or longer to fully dial in!

A lot of people need to learn how to properly count calories and put the fork down! Usually works and requires no medication. Most people are not hypothyroid.

 

[Deleted member 59947]

Start with 50mcg, possibly up to 75mcg. I wouldn’t raise it much higher then that considering her t3 dosage.

Personally for thyroid replacement therapy I usually recommend 50-100mcg t4 and 25-37.5mcg t3. Especially not higher in natural trainees.

Good luck and keep us posted on her results!

Thanks man.
Will definitely start her at 50mcgT3/day + 50mcg T4/day to see if she sheds weight at all in one months.
Will adjust from there and definitely keep you posted!

 

[Throwback]

Heres the deal on thyroid....
Tsh is the signal from your pituitary to the thyroid. They test TSH to determine if your thyroid is responding to that signal appropriately by producing enough T4. The lower the TSH value the more T4 your thyroid should produce. Optimal TSH targets are generally in the .5 to 1.5 range on a tsh test.
With a .5 to 1.0 tsh value above 1.75 to 2.5 ng/dl would be a normal expectation of T4. production.
Your body then converts T4 to T3.
Based on the above optimal situation of Tsh signal and the the thyroids T4 production, a value of 5 to 6.5 pg/ml would be a normal expectation of optimal conversion to T3.
There can be a few scenarios affecting all three of these values.
High TSH value typically results in a script for levothyroxcin to amp up thyroid t4 production. High Tsh values signal most endos that you are in a hypothyroid state. Yet without a t4 test they have no idea because they dont know what your thyroid production of T4 is.
If your T4 production is low you more than likley again are hypo thyroid because you are deficient in T4 and have not enough to convert to T3.
However if your T4 production is in the optimal range you may still be hypothyroid because you dont efficiently convert the adequate amount of T4 to T3.
This is where supplementation of t3 comes into play.
So in a nutshell low t4 will result in low t3 everytime.
Both t4 and t3 can be supplemented to address this.
Adequate t4 but low t3 should signal a supplementation of t3 to address the lack of t4 to t3 conversion.
Hope this helped.
Word of warning on t3 supplementation.....
T3 supplementation in the form of Liothyronine carries the risk of some very serious side effects like spiking blood sugar and bone density loss and a possibly terminal drug interaction with amphetamines.