The best supplements for liver to run all year round

[bigdaddyandfriends]

interesting, I didn't know Dutch had it too. most sources have 100mg with guaiacol (which is a full stop or me).

assume this is Dutch from Meso, in EU? There is a Dutch Pharma in USA too now (sponsor on ASF, not here), just ordered some mastE from him as it tested well and is scarce, and it's a compound I plan on running indefinitely so add to the stockpile when I can. don't recall seeing TNE on his priceless, assume the names are similar but sources are unrelated.

Arail's TNE is 50mg and still crashes sometimes at room temp. even if it looks good I through it on a mug warmer @ 162 degrees for a bit, never get any PIP when it's warm. I use 5mg daily along with 17.5mg testE as HRT - which together pretty well simulate normal diurnal variation - but have taken up to 25mg for preworkout / libido enhancement. Larger amounts do aromatize strongly, as expected, so I generally pre-treat 25mg TNE injections with aromasin - I'm a fairly heavy aromatizer, and also use 5mg MENT daily so already have 7a-ME2 floating around.

 

[armburst]

I’m interested in your prophylactic protocols for each system

I'm intersting to,my friend

 

[Photon]

interesting, I didn't know Dutch had it too. most sources have 100mg with guaiacol (which is a full stop or me).

assume this is Dutch from Meso, in EU? There is a Dutch Pharma in USA too now (sponsor on ASF, not here), just ordered some mastE from him as it tested well and is scarce, and it's a compound I plan on running indefinitely so add to the stockpile when I can. don't recall seeing TNE on his priceless, assume the names are similar but sources are unrelated.

Arail's TNE is 50mg and still crashes sometimes at room temp. even if it looks good I through it on a mug warmer @ 162 degrees for a bit, never get any PIP when it's warm. I use 5mg daily along with 17.5mg testE as HRT - which together pretty well simulate normal diurnal variation - but have taken up to 25mg for preworkout / libido enhancement. Larger amounts do aromatize strongly, as expected, so I generally pre-treat 25mg TNE injections with aromasin - I'm a fairly heavy aromatizer, and also use 5mg MENT daily so already have 7a-ME2 floating around.

Dutch for EU
Arail for US

Both on this board.

 

[armburst]

I noticed there's no Halo, have u tried it?
For inj glut, I'd recommend Korea Pharma, but if you can't source it then you can consider China pharma from SSA. Honestly speaking, i'd expect a daily injection of 700mg of glut to be superior vs all liver support supplements. NAC for instance, only has ~10% oral absorption rate, and then only a small amount of that converts to glut. TUDCA should be better than UDCA.

Dutch has 70mg/ml guaiacol free TNE too, I actually find TNE to blow all orals out of the water.

Are you offered my to inject 700mg daily glutathione? And what is TNE?

 

[Oswizzle]

Test No Ester … the magic ingredient for topical applications

 

[bigdaddyandfriends]

This is a lot of what I take. Obviously kidney, cardiovascular health, and lipids overlap...

Kidney:
Astragaloside IV
Cycloastrogenol
SS-31 (elamipretide) 5mg/day
Empoglaflozin 10mg

Blood pressure / cardiovascular:
Azilsartan 80mg* pm
Cilnip-T (Cilnidipine 10mg + telmisartan 40mg) am
Cialis 10mg am
Sildenafil 100mg pm

*until expensive supply exhausted then will replace with telmisartan 40mg for 80mg/day total, 120mg combined ARB doesn't seem to be causing any issue or much additional lowering of BP

Lipids:

Ezetimibe 10mg am
Pitavastatin 4mg pm
Ubiquinol 200mg am + pm
Pycnogenol 100mg am + pm
Cardabolic (SR9009 10mg/day + GW510516 8mg/day) inj

Mitochondrial / antioxidants:

MOTS-C 1mg
Methylene blue 10mg
PQQ 40mg/day
L-carnitine 600mg/day inj

Plus black seed oil, fish oil (EPA/DHA), borage oil, and lots of magnesium

Also experimenting with genistein (selective ERb agonist)

 

[ItCantBe]

Yau,guys.
What are you using for your liver? Give me some tips. I finished cycle and jumped on bridge. Cycle was test+npp+hexa+anavar. Bridge is test+mast+tirzapatide. After cycle my digestion became horrible,pain in right side. And yea I have hepatitis B,just please I know,I should stop with gera I know,but I wont. That's mine decision.
My plan to take some supplemets,like
Tudca 1g day 2 months
Nac 2g day 2 months

All year round i run 250mg nac, 250mg tudca. When using mild orals i bump that to 500 of each. When using heavy orals like anadrol, 1000mg of each.

If i ever start experiencing mild liver issues i go for an IV of glutathione and electrolytes.

 

[armburst]

This is a lot of what I take. Obviously kidney, cardiovascular health, and lipids overlap...

Kidney:
Astragaloside IV
Cycloastrogenol
SS-31 (elamipretide) 5mg/day
Empoglaflozin 10mg

Blood pressure / cardiovascular:
Azilsartan 80mg* pm
Cilnip-T (Cilnidipine 10mg + telmisartan 40mg) am
Cialis 10mg am
Sildenafil 100mg pm

*until expensive supply exhausted then will replace with telmisartan 40mg for 80mg/day total, 120mg combined ARB doesn't seem to be causing any issue or much additional lowering of BP

Lipids:

Ezetimibe 10mg am
Pitavastatin 4mg pm
Ubiquinol 200mg am + pm
Pycnogenol 100mg am + pm
Cardabolic (SR9009 10mg/day + GW510516 8mg/day) inj

Mitochondrial / antioxidants:

MOTS-C 1mg
Methylene blue 10mg
PQQ 40mg/day
L-carnitine 600mg/day inj

Plus black seed oil, fish oil (EPA/DHA), borage oil, and lots of magnesium

Also experimenting with genistein (selective ERb agonist)

Thank you,once again thank so much,my friend. Where did you find injectable sarms?

 

[armburst]

Thank you,once again thank so much,my friend. Where did you find injectable sarms?

Normaly meds I bought from BG guys,but he sucks sometimes. Only has medications what I need for normal price. I mean antidepressants and antipsichotics

 

[Matty_G]

This is a lot of what I take. Obviously kidney, cardiovascular health, and lipids overlap...

Kidney:
Astragaloside IV
Cycloastrogenol
SS-31 (elamipretide) 5mg/day
Empoglaflozin 10mg

Blood pressure / cardiovascular:
Azilsartan 80mg* pm
Cilnip-T (Cilnidipine 10mg + telmisartan 40mg) am
Cialis 10mg am
Sildenafil 100mg pm

*until expensive supply exhausted then will replace with telmisartan 40mg for 80mg/day total, 120mg combined ARB doesn't seem to be causing any issue or much additional lowering of BP

Lipids:

Ezetimibe 10mg am
Pitavastatin 4mg pm
Ubiquinol 200mg am + pm
Pycnogenol 100mg am + pm
Cardabolic (SR9009 10mg/day + GW510516 8mg/day) inj

Mitochondrial / antioxidants:

MOTS-C 1mg
Methylene blue 10mg
PQQ 40mg/day
L-carnitine 600mg/day inj

Plus black seed oil, fish oil (EPA/DHA), borage oil, and lots of magnesium

Also experimenting with genistein (selective ERb agonist)

Appreciate it

 

[Photon]

Lipids:
Cardabolic (SR9009 10mg/day + GW510516 8mg/day) inj

Do you have pre-post labwork for SR9009?

 

[bigdaddyandfriends]

Do you have pre-post labwork for SR9009?

No I’ve been using it for years, before I started checking bloods. I take it mainly for its protectiveness against cardiac remodeling but it is supposed to help with cholesterol too.

Cardarine is one of the few things that can raise HDL significantly, although I keep the dose very low.

SR9009 and GW510516 are not SARMs, they are metabolic modulators. My Cardabolic came from AminoAsylum but their new company doesn’t carry it. I think behemoth labs might have a version.

Cardarine/GW doesn’t need to be injected, SR does. Gong forward will probably just use ModernAminos SR9009 50mg/ml and oral GW. MAResearchchems and Kimerachems have injectables too.

 

[armburst]

No I’ve been using it for years, before I started checking bloods. I take it mainly for its protectiveness against cardiac remodeling but it is supposed to help with cholesterol too.

Cardarine is one of the few things that can raise HDL significantly, although I keep the dose very low.

SR9009 and GW510516 are not SARMs, they are metabolic modulators. My Cardabolic came from AminoAsylum but their new company doesn’t carry it. I think behemoth labs might have a version.

Cardarine/GW doesn’t need to be injected, SR does. Gong forward will probably just use ModernAminos SR9009 50mg/ml and oral GW. MAResearchchems and Kimerachems have injectables too.

I just ordered in dutch sarms those two,not inj. but in liquid forms

 

[Guna]

This is a lot of what I take. Obviously kidney, cardiovascular health, and lipids overlap...

Kidney:
Astragaloside IV
Cycloastrogenol
SS-31 (elamipretide) 5mg/day
Empoglaflozin 10mg

Blood pressure / cardiovascular:
Azilsartan 80mg* pm
Cilnip-T (Cilnidipine 10mg + telmisartan 40mg) am
Cialis 10mg am
Sildenafil 100mg pm

*until expensive supply exhausted then will replace with telmisartan 40mg for 80mg/day total, 120mg combined ARB doesn't seem to be causing any issue or much additional lowering of BP

Lipids:

Ezetimibe 10mg am
Pitavastatin 4mg pm
Ubiquinol 200mg am + pm
Pycnogenol 100mg am + pm
Cardabolic (SR9009 10mg/day + GW510516 8mg/day) inj

Mitochondrial / antioxidants:

MOTS-C 1mg
Methylene blue 10mg
PQQ 40mg/day
L-carnitine 600mg/day inj

Plus black seed oil, fish oil (EPA/DHA), borage oil, and lots of magnesium

Also experimenting with genistein (selective ERb agonist)

Is there any studies showing SS 31 having a positive impact on kidney markers?

 

[rockyraccoon]

Is there any studies showing SS 31 having a positive impact on kidney markers?

SS-31, a Mitochondria-Targeting Peptide, Ameliorates Kidney Disease - PMC

Mitochondria are essential for eukaryotic cell activity and function, and their dysfunction is associated with the development and progression of renal diseases. In recent years, there has been a rapid development in mitochondria-targeting ...

pmc.ncbi.nlm.nih.gov

 

[Nissan]

choline/inositol - 2000mg/day each

 

[eryximachus]

From some of my other posts here, people can probably tell I use a lot of things prophylactically to prevent problems from developing, my liver protocol is no exception. I do the same for kidneys, cardiovascularsystem, and insulin resistance - can post those too if anyone is interested.

I would love to see more info on this.

I'm in my late 40s and do well enough I'm devoting significant capital to whatever I can get my hands on, but prophylaxis is not commonly a goal here or elsewhere I get my info.

 

[Ghoul]

I would love to see more info on this.


I'm in my late 40s and do well enough I'm devoting significant capital to whatever I can get my hands on, but prophylaxis is not commonly a goal here or elsewhere I get my info.

What you're really talking about is going beyond "reactive medicince", which makes up the majority of healthcare. For instance, with lipids, "primary prevention" is largely a failure, with docs and patients not taking it seriously enough, while "secondary prevention" is a huge success. "Secondary prevention" is when the Preventative Cardiologist visits your bedside after you've had a heart attack or stroke, and prescribes the drugs that bring your lipids down to where they would've prevented the heart attack to begin with if it had been done sooner, and most patients find their fear of death overrides their fear of pills.

We're lucky to have both massive amounts of high quality data, and modern drugs to reach what have been solidly established numbers for maximizing longevity and healthspan. It wasn't long ago this stuff was a major crapshoot, and the compounds needed to optimize the factors involved caused all kinds of problems themselves.

In this order, the benefit of treating these things proactively is crystal clear:

BP
Lipids
Glucose
Inflammation

Along the way each improves end organ health and slows what had been considered "normal" aging damage.

Step one is to get a handle on your current numbers reflecting these factors.

Step two is finding the drugs that effectively improve each of these (some address more than one), keeping in mind combinations of lower dose meds that work via different mechanisms of action are better than higher dose single drugs, and of course, you need to ensure none of these "maintainance meds" cause damage to something else in the long term. Luckily, in every category there are drugs that meet that criteria, for most people.

 

[eryximachus]

This is a lot of what I take. Obviously kidney, cardiovascular health, and lipids overlap...

Kidney:
Astragaloside IV
Cycloastrogenol
SS-31 (elamipretide) 5mg/day
Empoglaflozin 10mg

Blood pressure / cardiovascular:
Azilsartan 80mg* pm
Cilnip-T (Cilnidipine 10mg + telmisartan 40mg) am
Cialis 10mg am
Sildenafil 100mg pm

*until expensive supply exhausted then will replace with telmisartan 40mg for 80mg/day total, 120mg combined ARB doesn't seem to be causing any issue or much additional lowering of BP

Lipids:

Ezetimibe 10mg am
Pitavastatin 4mg pm
Ubiquinol 200mg am + pm
Pycnogenol 100mg am + pm
Cardabolic (SR9009 10mg/day + GW510516 8mg/day) inj

Mitochondrial / antioxidants:

MOTS-C 1mg
Methylene blue 10mg
PQQ 40mg/day
L-carnitine 600mg/day inj

Plus black seed oil, fish oil (EPA/DHA), borage oil, and lots of magnesium

Also experimenting with genistein (selective ERb agonist)

You don't think GW510516 has a significant cancer risk?