If anyone from the future is interested, here is my 1st attempt. seems really good. the result is retin-A 0.1% cream
materials
scale, glass bowl, 190 proof grain alcohol, regular size silicon spatula, tiny silicon spatula, generic 450g moisturizer base cream, tretinoin powder.
procedure.
Tretinoin is a bright yellow which helps to see if materials are completely mixed visibly.
weighed .45g of tretinoin and emptied to the bottom of the glass bowl
a splash of alcohol. Like 2ml. Didn't completely dissolve but completely separated particles and removed air which ensured and aided complete mixing. mixed up with the large spatula.
added about a teaspoon of cream and mixed with a large spatula.
kept adding equal amounts to what was in the bowl and mixing until the container was empty. the little spatula was to aid large where unmixed parts at the top of large spatula and bowl would escape the mixture.