Very uneducated question about peptide raws

[Luke391]

Why would you need multiple years of unsterile raws that would be degrading over time because you didnt sterilize them? Make it make sense.

why would the raws degrade in powder form?

 

[Ghoul]

why would the raws degrade in powder form?

They are less stable, even in lyophilized form, in the absence of protective excipients. If you aren't going to brew and lyophilize them, they need to be stored in -80c cryofreezer, fully protected against moisture, preferably in a contained purged with nitrogen or argon (actually simple to do at home) to displace oxygen, in order to survive long term storage.

 

[Dial It In]

why would the raws degrade in powder form?

Why would they lyophilize them if they didn’t? I’m sure you can store them at some crazy subnegative temp to extend it. Prob need a cryo freezer for that and a few other handy dandy things you might not want to mess with.

 

[Ghoul]

what would happen if one was to use a unlyophilozed peptie? like would reconstituting a single dose and using right away avoid the degradation (obviosuly filtering)

I simplified the process in my explanation. One reason mannitol or glycine is used as a common excipient is because most peptides do not dissolve readily in water. Those sugars make dissolving much easier.

They also enhance conditions at the injection site to allow the peptide to permeate tissue and be absorbed.

So without it, the peptide won't work nearly as well.

 

[BigDadd7]

why would the raws degrade in powder form?

Magic

 

[Sampei]

Are you wanting to add mannitol when you reconstitute? Mannitol is already added to a lot of peptides to help with that caking, some have sorbitol. Not sure I’m tracking what you are trying to do. If you are trying to lyphilize peptide then most need some sort of bulking agent like mannitol for stabilization. I’m not as familiar with peptide raws but maybe I can get someone in here to help with tons of knowledge and of the smartest fellas round here. @Sampei

The lyophilizing idea is a shit one, he can just reconstitute the raw and filter the solution into a sterile vial. I have a chemist friend doing it regularly, he uses it for no long than 4 weeks.

It works.

Anything else is expensive as fuck and Need a professional setup that the dude can't even understand plus he can't afford it.

Btw if he had good contact there are sources that can make you raw on demand already mixed with preservatives and you can reconstitute it directly extending the shelf life but it's unnecessary, just reconstitute every 2/3 weeks a vial and that's it.

Still a lot of work for not reason as Tirzepatide is cheap as fuck. Plus you need to be sure to get good raws etc.

 

[Sampei]

This whole fuckery is great only if you sell ready to inject pen to ppl, selling two shot pen so that the shelf life of the solution is not important and you can of course this way increase your ROI

 

[dinfar1337]

This whole fuckery is great only if you sell ready to inject pen to ppl, selling two shot pen so that the shelf life of the solution is not important and you can of course this way increase your ROI

i cant tell too much about selling since i dont wanna get banned again.

but holy fuck even such a small country as denmark has so so much profit in these fat loss drugs.

i dont believe sigma audleys 10 million they made were even close to 10% of total illegal glp sales yearly.

 

[Sampei]

why would the raws degrade in powder form?

You ask these questions and wanna lyo your own GLP-1?
You are such a joke, I told you already, you need mental help and a specialist to try fix your mental fuckery.

 

[Dial It In]

You ask these questions and wanna lyo your own GLP-1?
You are such a joke, I told you already, you need mental help and a specialist to try fix your mental fuckery.

I figured you’d come clean this up. I was trying to get the why on all this and it looks like there might be more to the story. Appreciate ya brother

 

[Spaceman Spiff]

You ask these questions and wanna lyo your own GLP-1?
You are such a joke, I told you already, you need mental help and a specialist to try fix your mental fuckery.

I need to save a few dollars broski

 

[dinfar1337]

I figured you’d come clean this up. I was trying to get the why on all this and it looks like there might be more to the story. Appreciate ya brother

took me 3 year education to work at novo nordisk

i still had trouble setting it up at home without all the fancy machines and manufacturing the raw powder with their automatic machines from start.

 

[Dial It In]

took me 3 year education to work at novo nordisk

i still had trouble setting it up at home without all the fancy machines and manufacturing the raw powder with their automatic machines from start.

It’s not worth the risk for me to buy all the stuff I need then get raws and then mess it up anyway. I’ll just buy it finished and let that be that. Welcome back also from purgatory

 

[dinfar1337]

It’s not worth the risk for me to buy all the stuff I need then get raws and then mess it up anyway. I’ll just buy it finished and let that be that. Welcome back also from purgatory

thank you.

also the novo nordisk machinery from a lab defiently adds up to somewhere around 1 million+(just the lab i have for myself)

what i have built at home can make 5 peptides vials every 3-4 hours. and the dosing could be more accurate. this also requires alot of manual work.

it would truly only be worth to invest in a decent 100k+ setup if you were the chinese. no one of us can license such machinery.

best ill get is probably around 10k range.

 

[Dial It In]

thank you.

also the novo nordisk machinery from a lab defiently adds up to somewhere around 1 million+(just the lab i have for myself)

what i have built at home can make 5 peptides vials every 3-4 hours. and the dosing could be more accurate. this also requires alot of manual work.

it would truly only be worth to invest in a decent 100k+ setup if you were the chinese. no one of us can license such machinery.

best ill get is probably around 10k range.

And I can buy a rest of what life I got left in peptides for 10K. I’ll just get em from those already invested

 

[dinfar1337]

And I can buy a rest of what life I got left in peptides for 10K. I’ll just get em from those already invested

my hgh usage defiently adds to 1k yearly. still 15 year investment just to make that back.


but you have to be a really big hoarder to even bother

 

[Luke391]

The lyophilizing idea is a shit one, he can just reconstitute the raw and filter the solution into a sterile vial. I have a chemist friend doing it regularly, he uses it for no long than 4 weeks.

It works.

Anything else is expensive as fuck and Need a professional setup that the dude can't even understand plus he can't afford it.

Btw if he had good contact there are sources that can make you raw on demand already mixed with preservatives and you can reconstitute it directly extending the shelf life but it's unnecessary, just reconstitute every 2/3 weeks a vial and that's it.

Still a lot of work for not reason as Tirzepatide is cheap as fuck. Plus you need to be sure to get good raws etc.

ok thanks
so the degradation of the raw powder would be negligible? like making single dose vials.

What about stuff like AICAR? that is also dosed orally so does it mean the raw powder is less susceptable to degradin?

 

[Luke391]

I need to save a few dollars broski

better to ask and be a fool for a day than not ask and be a fool for life

 

[IndividualMan]

What about stuff like AICAR?

most of those thingies that came up around the same time as Sarms do not degrade much, if at all.