MESO-Rx
Anabolic Steroids
winny tabs/ winstrol injectable
- Thread starter sable
- Start date
sc0rcher
New Member
Got some of the renvex winstrol too. Gg to use it to end my 20 week cycle with renvex test/mast props.. hope it's gtg.
blazinshotguns
New Member
Why winny ? That stuff was junk and it cost the same as tren . Made my joints Hurt that's it
sc0rcher
New Member
I afraid of tren... love my sleep now...
Same here. My line of work requires me to be early and courteous. Which neither goes well with tren.lolTANGO.ECHO.KILO
Member
I've had good results running winny low in the background. I can't get too liberal with my dosage though before the sides start to overshadow the small increase in gains.
I second that. Last cycle I had with Geneza inj winny was a killer on my ankles. Shit was strong like a mofo.. Also since I play racquet ball and handle for cardio. My ankles literally swole up from the winny.
I had to cut down to eod injections.
Never done oral winny so maybe it'll be a little different. Def going to keep dosages as minimal as I can without sacrificing gains.
I had to cut down to eod injections.
Never done oral winny so maybe it'll be a little different. Def going to keep dosages as minimal as I can without sacrificing gains.
Not handle..*handball*
TANGO.ECHO.KILO
Member
Interesting. I can't remember any actual inflammation or swelling but my joints do get dry and it is compounded by the increased weight I wanna push from the strength gains when I'm on. Hits me more like a dull ache, but it's deep and annoying none the less. Rather than run Depot high I am having good success running some Mast ED and then the winny orally at around 50 MG ED. That will put me on the higher end of dosing for the DHT's but offsets the price of Mast and the sides of high winny. My tabs are 50mg and I was taking them an hr pwo but now cut them in half and dose every 12 hours. Don't know if it makes a difference yet but I have a few weeks to explore it further.
Jimmyinkedup
New Member
Test, deca or NPP, winny = excellent stack.
winny also occupies but dies not activate prog receptor site making it an excellent counterpart to a stack with deca (or tren if you dont get joint issues).
Also I always just run it orally personally.
winny also occupies but dies not activate prog receptor site making it an excellent counterpart to a stack with deca (or tren if you dont get joint issues).
Also I always just run it orally personally.
TANGO.ECHO.KILO
Member
Jimmy can you expand on that second point? Winny + proges?
Jimmyinkedup
New Member
Ellis AJ, Cawston TE, Mackie EJ.
Rheumatology Research Unit, Addenbrooke's Hospital, Cambridge, UK.
The anabolic steroid stanozolol stimulates the production of prostaglandin E2 (PGE2) and the matrix metalloproteinases collagenase and stromelysin in human skin fibroblasts but not in rheumatoid synovial fibroblasts. The basis for these differential responses was investigated at the levels of DNA synthesis and steroid receptor binding. Stanozolol inhibited fibroblast growth factor (FGF)-stimulated DNA synthesis in both the skin and synovial fibroblasts, showing that both cell types were capable of responding to the compound. Competitive binding assays indicated that stanozolol bound specifically to both the skin and synovial fibroblasts. Binding of stanozolol to both cell types could be partially displaced by progesterone, indicating that stanozolol binds to the progesterone receptor. Immunocytochemical studies confirmed the presence of progesterone receptors on skin and synovial fibroblasts. However, progesterone failed to elicit any response with respect to collagenase production in either cell type. Nortestosterone, dexamethasone and 17 beta-oestradiol had no effect on binding of stanozolol to either cell type. These results indicate that the inhibition of DNA synthesis by stanozolol is elicited through the progesterone receptor. The effects of stanozolol on collagenase and PGE2 production are mediated by a different receptor, present on skin but not synovial fibroblasts, and as yet unidentified.
Rheumatology Research Unit, Addenbrooke's Hospital, Cambridge, UK.
The anabolic steroid stanozolol stimulates the production of prostaglandin E2 (PGE2) and the matrix metalloproteinases collagenase and stromelysin in human skin fibroblasts but not in rheumatoid synovial fibroblasts. The basis for these differential responses was investigated at the levels of DNA synthesis and steroid receptor binding. Stanozolol inhibited fibroblast growth factor (FGF)-stimulated DNA synthesis in both the skin and synovial fibroblasts, showing that both cell types were capable of responding to the compound. Competitive binding assays indicated that stanozolol bound specifically to both the skin and synovial fibroblasts. Binding of stanozolol to both cell types could be partially displaced by progesterone, indicating that stanozolol binds to the progesterone receptor. Immunocytochemical studies confirmed the presence of progesterone receptors on skin and synovial fibroblasts. However, progesterone failed to elicit any response with respect to collagenase production in either cell type. Nortestosterone, dexamethasone and 17 beta-oestradiol had no effect on binding of stanozolol to either cell type. These results indicate that the inhibition of DNA synthesis by stanozolol is elicited through the progesterone receptor. The effects of stanozolol on collagenase and PGE2 production are mediated by a different receptor, present on skin but not synovial fibroblasts, and as yet unidentified.
Jimmyinkedup
New Member
The point is this - thats not the main reason I would take winny BUT it does possibly help to explain the ancedotal synergy reported for years especially with winstrol and deca. Deca is a progestin, Tren is likely a preogestin, if winny does what this study indicates the main benefit would be the effect of ptentially mangaing progesterone in males which there is currently no substance that can effectiveky be utilized to do so. No practical meds are available to do this. By winny occupying the prgesterone recpptor, the effects of a preogestin activating it could be negated.
TANGO.ECHO.KILO
Member
Thanks yes I've heard plenty of opinions on this but I've read many of your posts and know your well educated so I appreciate you shedding some more light on the subject. I currently running tren a/mast/winny and they def have an interesting synergy. I have pharma Adex and Caber but so far have not had to get in to the caber. This is quality stuff thanks for posting!
