MK-677 and Insulin (R) Only Cycle

[TRT]

So I need some experience on this subject. Looked around for a little bit and couldn't find what I was looking for so maybe someone can chime in. First hand knowledge or better understanding of the two is fine.

I'm looking to take Mk-677 to try and duplicate the effects similar to using GH. I was gonna take it before bed (possibility being lethargic) but since I'm using insulin that might be a bad idea. Ha First thing in the morning would be best for that. Both last for a long period of time but as far as timing goes should I be taking both together? Or mk on an empty stomach and shortly after taking the slin? Should I split my mk dose up morning and pre workout?
Also, for those of you who have experience with this your input as far as results go is appreciated. Thank you.

 

[fodsod]

I've run MK both ways. In the morning on an empty stomach and before bed 2 hours after eating (both at 30 mgs). I had bloods drawn with with morning dose regimen after 35 days and saw a 70 point jump in IGF so I'd say start there. I've also run it by itself and on top of 5 ius of HGH ED.

I think MK's effect/process is very different than using actual HGH so I don't think combining it with slin will produce the same effect as slin and HGH timed out during the day. Just my opinion.

 

[Wunderpus]

The purpose, at least for myself, of running insulin with GH is mostly due to the fact high doses of exogenous GH lower insulin sensitivity. You will put on some weight with insulin, but I worry it will be more fat cells than muscle tissue. Remember, insulin is equally anabolic to fat as it is to muscles, hence why insulin timing is so important (use when the muscle cells are prioritized for nutrient partitioning).

Also, the "effects" of insulin are overhyped, much like the sides from tren or the hepatoxicity of many orals. Now, you are taking a big risk for what I believe is little potential reward.

Using an "R" insulin is also not my ideal scenario for you, I'd rather see the fastest (log) option. I would like it to be in, and out, quickly. No double peak etc.

So, the million dollar question... If I were TO experiment using MK-677 and insulin alone, how would I do it? I would take the MK-677 8 hours pre workout, and then the insulin immediately post workout. The below study is actually very, very educational (I just read it) and would highly recommend it to anyone interested in MK-677. I think I might try this stuff, now.


Oral Administration of Growth Hormone (GH) Releasing Peptide-Mimetic MK-677 Stimulates the GH/Insulin-Like Growth Factor-I Axis in Selected GH-Deficient Adults* | The Journal of Clinical Endocrinology & Metabolism | Oxford Academic

 

[fodsod]

The purpose, at least for myself, of running insulin with GH is mostly due to the fact high doses of exogenous GH lower insulin sensitivity. You will put on some weight with insulin, but I worry it will be more fat cells than muscle tissue. Remember, insulin is equally anabolic to fat as it is to muscles, hence why insulin timing is so important (use when the muscle cells are prioritized for nutrient partitioning).

Also, the "effects" of insulin are overhyped, much like the sides from tren or the hepatoxicity of many orals. Now, you are taking a big risk for what I believe is little potential reward.

Using an "R" insulin is also not my ideal scenario for you, I'd rather see the fastest (log) option. I would like it to be in, and out, quickly. No double peak etc.

So, the million dollar question... If I were TO experiment using MK-677 and insulin alone, how would I do it? I would take the MK-677 8 hours pre workout, and then the insulin immediately post workout. The below study is actually very, very educational (I just read it) and would highly recommend it to anyone interested in MK-677. I think I might try this stuff, now.


Oral Administration of Growth Hormone (GH) Releasing Peptide-Mimetic MK-677 Stimulates the GH/Insulin-Like Growth Factor-I Axis in Selected GH-Deficient Adults* | The Journal of Clinical Endocrinology & Metabolism | Oxford Academic

Good article bro.

 

[TRT]

I've run MK both ways. In the morning on an empty stomach and before bed 2 hours after eating (both at 30 mgs). I had bloods drawn with with morning dose regimen after 35 days and saw a 70 point jump in IGF so I'd say start there. I've also run it by itself and on top of 5 ius of HGH ED.

I think MK's effect/process is very different than using actual HGH so I don't think combining it with slin will produce the same effect as slin and HGH timed out during the day. Just my opinion.

Ya. I'm leaning towards this. I'm actually glad to hear it's not as beneficial.

 

[TRT]

I think I might skip on the slin. Used it plenty of times but I'd rather save it for the GH. Thank you both. I'm open to different options. Good article.

 

[Sk8man101]

All the stuff I hear about mk-677 sounds to good to be true to me.
I feel like if it were all that great everyone would be doing it instead of hgh.
Still I'm gunna sub this just cause I wanna see how these results turn out.
@TRT can you keep updates on how hungry it makes you? That's what most intrests me.

 

[TRT]

Oh, ya. For sure. I'll give all details and post them here. I'll know if it makes me any hungrier alright. Ha Hope I don't eat myself out of house and home.

 

[fodsod]

All the stuff I hear about mk-677 sounds to good to be true to me.
I feel like if it were all that great everyone would be doing it instead of hgh.
Still I'm gunna sub this just cause I wanna see how these results turn out.
@TRT can you keep updates on how hungry it makes you? That's what most intrests me.

I wouldn't say it's "great" as it's effect for me personally is a fraction of what GH is but it does appear to actually have some effect on GH levels and did increase my IGF levels after 35 days at 30 mg ED even while on actual GH for 5 months.

So I'll say it's sort of like taking 1-2ui a day of GH or so in some ways. It's hard to say exactly what any one person will get from that low amount.

For me it was just like adding an extra IU or two on top of the 5 I was already running. I could definitely tell a difference in my look, my side effects were worse and I could eat more crap and not put on fat.

I'm just now starting a run of MK677 at 50 mg ED split into 30mg in the morning and 20 mg at night before bed. I'll be testing IGF levels after about a month.

I'm off GH until this is done and I'm currently running 1250 mg of Test E and 600-800 mg if EQ with .50 of adex daily. I'll post my labs once I've got them.

 

[Roco Bama]

I wouldn't say it's "great" as it's effect for me personally is a fraction of what GH is but it does appear to actually have some effect on GH levels and did increase my IGF levels after 35 days at 30 mg ED even while on actual GH for 5 months.

So I'll say it's sort of like taking 1-2ui a day of GH or so in some ways. It's hard to say exactly what any one person will get from that low amount.

For me it was just like adding an extra IU or two on top of the 5 I was already running. I could definitely tell a difference in my look, my side effects were worse and I could eat more crap and not put on fat.

I'm just now starting a run of MK677 at 50 mg ED split into 30mg in the morning and 20 mg at night before bed. I'll be testing IGF levels after about a month.

I'm off GH until this is done and I'm currently running 1250 mg of Test E and 600-800 mg if EQ with .50 of adex daily. I'll post my labs once I've got them.

You should expect baseline IGF to be elevated by 160% if your mk677 is legit. So your IGF levels should be around 450 after 30 days. Don't touch any hgh in that 30 days experiment.
Good luck

 

[TRT]

I wouldn't say it's "great" as it's effect for me personally is a fraction of what GH is but it does appear to actually have some effect on GH levels and did increase my IGF levels after 35 days at 30 mg ED even while on actual GH for 5 months.

So I'll say it's sort of like taking 1-2ui a day of GH or so in some ways. It's hard to say exactly what any one person will get from that low amount.

For me it was just like adding an extra IU or two on top of the 5 I was already running. I could definitely tell a difference in my look, my side effects were worse and I could eat more crap and not put on fat.

I'm just now starting a run of MK677 at 50 mg ED split into 30mg in the morning and 20 mg at night before bed. I'll be testing IGF levels after about a month.

I'm off GH until this is done and I'm currently running 1250 mg of Test E and 600-800 mg if EQ with .50 of adex daily. I'll post my labs once I've got them.

Good deal. This is something I could easily dive head first into. Thank you for your input and experience it's helping me and others see exactly how mk-677 is reacting with or without GH. I have some questions about that study I didn't understand but I'll go over them later seeing as how I'm driving. Ha thanks again.

 

[TRT]

I'd like to see the blood results from other members in the dosing and effectiveness aspect. Then I'll take X amount and take an ACE inhibitor to see if that's fact or fiction. Obviously IGF test while on the Mk and then take the ACE inhibitor followed by another. The length of time in between blood test and taking both we can determine when we get there.