To be a contrarian, my last tren run was 50 mg/day injected subq with a 0.5" 29-gauge syringe. My previous tren runs were also injected subq, but were of lower dosages (140 and 210).
350/week was a great dosage for me: minimal side effects and great progress, and it was sustainable up until week 12, when I chose to stop it (not because of side effects).
Conversely, the 140 and 210 runs were stopped after < 4 weeks due to typical tren side effects.
It should be noted that with the 350 run, test was lower than tren, and in the other 2 runs, test was higher. I was also taking Seroquel to combat insomnia during the 350 run. Seroquel did not work when test was higher than tren.