Your doctor is incorrect. I will post late the study on PIN & TRT. In the meantime, read the following and send to your doctor - https://thinksteroids.com/community/threads/134335754
For Full-Text [PDF] Email
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mscally@alum.mit.edu
MESO-Rx
Anabolic Steroids
Stopping Testosterone Replacement?
- Thread starter Johnny Trackmarks
- Start date
Your doctor is incorrect. I will post late the study on PIN & TRT. In the meantime, read the following and send to your doctor - https://thinksteroids.com/community/threads/134335754
For Full-Text [PDF] Email
At age 77, what was the reason for the biopsy?
Rhoden EL, Morgentaler A. Testosterone replacement therapy in hypogonadal men at high risk for prostate cancer: results of 1 year of treatment in men with prostatic intraepithelial neoplasia. J Urol 2003;170(6 Pt 1):2348-51. ScienceDirect.com - The Journal of Urology - Testosterone Replacement Therapy in Hypogonadal Men at High Risk for Prostate Cancer: Results of 1 Year of Treatment in Men With Prostatic Intraepithelial Neoplasia
PURPOSE: One of the greatest concerns among clinicians regarding testosterone replacement therapy (TRT) is the fear of causing or promoting prostate cancer. We evaluated prostatic changes in hypogonadal men with and without high grade prostatic intraepithelial neoplasia (PIN), which is considered a prostatic precancerous lesion, after 1 year of TRT.
MATERIALS AND METHODS: A total of 75 hypogonadal who completed 12 months of TRT were studied. All underwent prostate biopsy prior to initiating treatment. Of the men 55 had benign prostate biopsies (PIN-) and 20 had PIN without frank cancer (PIN+). All men with PIN underwent repeat biopsy to exclude cancer prior to the initiation of testosterone treatment. Prostate specific antigen (PSA), and total and free testosterone were determined prior to treatment and at 1 year. Repeat biopsy was performed for a change noted on digital rectal examination or for a PSA increase of 1 ng/l or greater.
RESULTS: PSA was similar at baseline in men with and without PIN (1.49 +/- 1.1 and 1.53 +/- 1.6 ng/dl, p >0.05) and after 12 months of TRT (1.82 +/- 1.1 and 1.78 +/- 1.6 ng/dl, respectively, p >0.05). A slight, similar increase in mean PSA was noted in the PIN- and PIN+ groups (0.25 +/- 0.6 and 0.33 +/- 0.6 ng/dl, p >0.05). One man in the PIN+ group had cancer after biopsy was performed due to abnormal digital rectal examination. Four additional men in the PIN- group and 2 in the PIN+ group underwent re-biopsy for elevated PSA and none had cancer. No differences were noted between the PIN- and PIN+ groups with regard to total and free testosterone at baseline and at 1 year (p = 0.267).
CONCLUSIONS: After 1 year of TRT men with PIN do not have a greater increase in PSA or a significantly increased risk of cancer than men without PIN. These results indicate that TRT is not contraindicated in men with a history of PIN.
Rhoden EL, Morgentaler A. Testosterone replacement therapy in hypogonadal men at high risk for prostate cancer: results of 1 year of treatment in men with prostatic intraepithelial neoplasia. J Urol 2003;170(6 Pt 1):2348-51. ScienceDirect.com - The Journal of Urology - Testosterone Replacement Therapy in Hypogonadal Men at High Risk for Prostate Cancer: Results of 1 Year of Treatment in Men With Prostatic Intraepithelial Neoplasia
PURPOSE: One of the greatest concerns among clinicians regarding testosterone replacement therapy (TRT) is the fear of causing or promoting prostate cancer. We evaluated prostatic changes in hypogonadal men with and without high grade prostatic intraepithelial neoplasia (PIN), which is considered a prostatic precancerous lesion, after 1 year of TRT.
MATERIALS AND METHODS: A total of 75 hypogonadal who completed 12 months of TRT were studied. All underwent prostate biopsy prior to initiating treatment. Of the men 55 had benign prostate biopsies (PIN-) and 20 had PIN without frank cancer (PIN+). All men with PIN underwent repeat biopsy to exclude cancer prior to the initiation of testosterone treatment. Prostate specific antigen (PSA), and total and free testosterone were determined prior to treatment and at 1 year. Repeat biopsy was performed for a change noted on digital rectal examination or for a PSA increase of 1 ng/l or greater.
RESULTS: PSA was similar at baseline in men with and without PIN (1.49 +/- 1.1 and 1.53 +/- 1.6 ng/dl, p >0.05) and after 12 months of TRT (1.82 +/- 1.1 and 1.78 +/- 1.6 ng/dl, respectively, p >0.05). A slight, similar increase in mean PSA was noted in the PIN- and PIN+ groups (0.25 +/- 0.6 and 0.33 +/- 0.6 ng/dl, p >0.05). One man in the PIN+ group had cancer after biopsy was performed due to abnormal digital rectal examination. Four additional men in the PIN- group and 2 in the PIN+ group underwent re-biopsy for elevated PSA and none had cancer. No differences were noted between the PIN- and PIN+ groups with regard to total and free testosterone at baseline and at 1 year (p = 0.267).
CONCLUSIONS: After 1 year of TRT men with PIN do not have a greater increase in PSA or a significantly increased risk of cancer than men without PIN. These results indicate that TRT is not contraindicated in men with a history of PIN.
Thank you for your response.
After 11 days without shot I felt horrible, mentally, physically, I went back to the injections yesterday.
My Urologist is out of town for several days. When he gets back I am going to confront him with these studies.
The side affects I cant live with. If I develop Cancer I will have my prostrate removed. I don't need it.
What are your thoughts about this?
After 11 days without shot I felt horrible, mentally, physically, I went back to the injections yesterday.
My Urologist is out of town for several days. When he gets back I am going to confront him with these studies.
The side affects I cant live with. If I develop Cancer I will have my prostrate removed. I don't need it.
What are your thoughts about this?
Whatever you decide, from what I've heard, you cant or shouldn't stop TEST cold turkey. Ive only been on TEST-C for a year and never experienced a withdrawal, but I heard that it's more fun to have teeth pulled. If you are going to stop, you probably would want to taper down. I cant tell you what you should do, but if it was me...more than likely I wouldn't stop the injections, but then again, I'm not in your shoes.
What is the solution?
Thats incorrect. If he is low on T he is most probably low in E2 aswell. As far as I know when there is no substrate for aromatization, then you4 end up with low e2 aswell. So crazy anxiety is most probably due to low T and low E2.Johnny, the ANXIETY is the feelling of ESTROGEN ass raping you like some fukin cunt with a strapon...
Keri. Save the queerbait inquisition into age. The post looked normal to me. Not all of us can be fucking addonis till freakin 60/... SOrry, just save that shit. 40 IS a BIG one any way you slice it....
I don't even recall scribing that post but WOW you really dragged this one up out of the cellar didn'tCHA...
But WRONG.. You can trust me when I say (and short of being really fit and going low on T as a sudden interrupt) that you will NEVER have a problem as a shortage of Estrogen... E IS the OMEGA, The Reaper, and THE END... E2 also feeds E3 which is in fact cancer in a can. E is the MAJORITY signaler of T production shutdown in MOST Males. THE BODY STOPS T PRODUCTION BECAUSE Estrogen production has gone to high (in most cases). Gone too high due to fat aromatization. The only way to stay ahead of E is to be up on your T&Androgens. The only way to do that is to be able to metabolize T into a healthy A-to-E ratio via PHYSICAL WORK. Once that capacity is gone, so will you be, sooner or later... In short, to remain healthy as an adult, you will spend your life running from SATAN... And the faster the better it turns out....
The conundrum is exponentiated today via exposure to plasticizers, PFOAs, etc. Which the body interprets as estrogens and even prematurely hinder natural T production.
Hint - Its about BALANCE...
lukiss96
Member
Holy shit man, the year is 2022 not 2012...
C'mon man, it's only 10 years ago!
malfeasance
Member
Still, I wonder if Johnny Trackmarks got his libido back and started giving it to the old lady again, or if she started up with the neighbor, divorced him, took the house and his retirement, and now he is homeless in Cleveland with winter approaching.
