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Great articles, thanks.Effects of GH/IGF axis on bone and cartilage - PMC
Growth hormone (GH) and its mediator, the insulin-like growth factor-1 (IGF-1) regulate somatic growth, metabolism and many aspects of aging. As such, actions of GH/IGF have been studied in many tissues and organs over decades. GH and IGF-1 are part ...www.ncbi.nlm.nih.gov
Fig. 4
Hormones and growth factors in the pathogenesis of spinal ligament ossification - PMC
Ossification of the spinal ligaments (OSL) is a pathologic condition that causes ectopic bone formation and subsequently results in various degrees of neurological deficit, but the etiology of OSL remains almost unknown. Some systemic hormones, such ...www.ncbi.nlm.nih.gov
The mechanism seems to be there for GH abuse to make OA or joint deterioration / degeneration markedly worse.
Yeah I should have said "preexisting" OA or disk degeneration above. The last thing you want at an already diseased site is osteophyte growth. Some should not be loading their spines at all since this will potentially make osteophytes worse. Painful, but you still gotta getbig or die tryin.Great articles, thanks.
Seems like a "maybe" or "it's possible" type of situation. Probably depends a lot on dosage, length of use, genetics, amongst many other factors.
