Trizepatide tips / tricks

[runitback]

What's up Meso
I am starting Triz and want to ask those who are using it for any tips when first stating
Thanks for the feedback

 

[SubparMarioBro]

The problem with those studies who concludes that glp 1 can make you lose muscle

The reality it’s just way harder in term of appetite to eat a lot of protein especially meat with it
And you desire to eat some meat isn’t really there
That’s probably why they lost muscles at the end

They probably didn’t workout and didn’t eat any protein at all due to the fact they are way harder to Digest (protein)

I was going to post something about this later, weaponized bro science, but it’s definitely worth keeping in mind that most of these trials basically just give you a drug that will cause you to lose a ton of weight and say “you could also eat healthier and exercise, that’ll help, good luck”. The results largely reflect what you’d expect from pharmacologically-induced anorexia. You’ll lose weight if you lean really hard on the first half of the CICO equation, that obviously works. But there’s probably low-hanging fruit for body composition improvements compared to the clinical trial results.

 

[FuriousGrill]

I was going to post something about this later, weaponized bro science, but it’s definitely worth keeping in mind that most of these trials basically just give you a drug that will cause you to lose a ton of weight and say “you could also eat healthier and exercise, that’ll help, good luck”. The results largely reflect what you’d expect from pharmacologically-induced anorexia. You’ll lose weight if you lean really hard on the first half of the CICO equation, that obviously works. But there’s probably low-hanging fruit for body composition improvements compared to the clinical trial results.

Don't really think this applies to all to our specific demographic (guys who are on AAS + GH + exercise hard and eat enough protein). In fact, lots of people lost virtually no muscle dieting HARD on just TRT + Tirz + exercise/protein.

 

[SubparMarioBro]

Don't really think this applies to all to our specific demographic (guys who are on AAS + GH + exercise hard and eat enough protein). In fact, lots of people lost virtually no muscle dieting HARD on just TRT + Tirz + exercise/protein.

Absolutely, I suspect you can get much better results than seen in clinical trials if you optimize the basic things we already know about.

You’re competing against the “I take my shot every week and I can barely eat an entire Big Mac the next day” folks for body comp results…

 

[Anonymous35]

Absolutely, I suspect you can get much better results than seen in clinical trials if you optimize the basic things we already know about.

You’re competing against the “I take my shot every week and I can barely eat an entire Big Mac the next day” folks for body comp results…

Yep those folks in those studies didn’t workout
And without glp1 if you go cico without exercice you will lose muscle in the process

 

[CraneKraken]

I'd suggest keeping a bottle of Tums by the bed. This was a lifesaver for me. The acid reflux early on can be pretty severe. It was for me anyhow and I usually tolerate sides really well.

 

[y777]

What's up Meso
I am starting Triz and want to ask those who are using it for any tips when first stating
Thanks for the feedback

get some orally dissolving ondasetron tablets. GLP-1s can cause nausea just on their own. i still get it and have been on these drugs for a couple of years, both UGL and pharma grade. tirz and sema.

 

[Anonymous35]

I'd suggest keeping a bottle of Tums by the bed. This was a lifesaver for me. The acid reflux early on can be pretty severe. It was for me anyhow and I usually tolerate sides really well.

You can also used some omeprazole if it’s too strong

I have a lot of acid reflux during my bulking phase and then i develop esphagitis

 

[Anonymous35]

get some orally dissolving ondasetron tablets. GLP-1s can cause nausea just on their own. i still get it and have been on these drugs for a couple of years, both UGL and pharma grade. tirz and sema.

Maybe you used too much if you need this kind of pills ?

 

[Mrhairyman]

Has anyone experience any stomach issues while taking orals ( dbol,Tbol,var etc) while on Triz ?

 

[mikeh1998]

Has anyone experience any stomach issues while taking orals ( dbol,Tbol,var etc) while on Triz ?

I have tried taking var and it's just impossible. Insane acid reflux that lasts a full 36 hours if I take anavar for 2 days in a row. Antacids don't help. Could just be me.

 

[Anonymous35]

Has anyone experience any stomach issues while taking orals ( dbol,Tbol,var etc) while on Triz ?

Yep me, throwing up multiple time at the gym

 

[runitback]

Has anyone blasted gear while on Triz ?
No plans to blast anytime soon, but am curious

 

[Anonymous35]

Has anyone blasted gear while on Triz ?
No plans to blast anytime soon, but am curious

Yes me during a cut

 

[psauce]

I have tried taking var and it's just impossible. Insane acid reflux that lasts a full 36 hours if I take anavar for 2 days in a row. Antacids don't help. Could just be me.

Did you try the whole stomach acid therapy spectrum? Asking because I know you are not the only person who experiences this symptom, and most people don't know the systematic approach to addressing it.

The first thing to try is antacids, which I am sure everyone knows. TUMS or Mylanta in the US -- something to raise the pH of stomach fluids.

If that is insufficient, the next step up is something called an acid reducer or an H2 blocker. The most common brand name in the US is Pepcid, generic name famotidine.

If those aren't enough, the last step is the proton pump inhibitors. Common brand names in the US are Prilosec or Nexium, the OTC generics are omeprazole and esomeprazole.

The first two are more or less immediate, the third is something you take every day and is long acting. They also all work in concert; you can find Pepcid Complete, which is a chewable tablet that combines an antacid with an acid reducer (calcium carbonate with famotidine). You can eat those while taking omeprazole every morning.

I took relatively big whacks of semaglutide and had ungodly heartburn when I overindulged, took Anavar, or both. I was able to get it under control, and tolerated the occasional dietary indiscretion and all of my orals with nothing more than some hiccupping.

TLDR: try TUMS, then Pepcid, then Prilosec, then all three together if you need to. If that's not enough, you gotta throw in the towel or modify your protocol.

 

[runitback]

Very fatty and fried foods seem to induce sides more readily. Really learn to listen to your appetite. Forget regular meals or eating on "automatic". Eat when you genuinely feel physical hunger, small portions, stop the moment you feel full. This is truly the most important technique for avoiding sides.

If you notice no appetite suppression the first week. Feel free to titrate up the next week. Some feel the effect at the starting dose, but many (males
especially) feel nothing until 5mg or 7.5mg. But once you start feeling it, give it two doses before deciding whether to go up again. It takes two weeks to really get a handle on the maximum effect of a given dose. You can remain at a dose as long as you like, but once appetite suppression. diminishes and you're not yet at goal weight, titrate up.

On Week 7, currently @ 5mg. and feel nothing
Following suggested guidelines and ti-trading up 2.5 every 4 weeks.
At what dose did you start feeling the effects ?
Hoping it will start to kick in @ 7

 

[Ghoul]

On Week 7, currently @ 5mg. and feel nothing
Following suggested guidelines and ti-trading up 2.5 every 4 weeks.
At what dose did you start feeling the effects ?
Hoping it will start to kick in @ 7

7.5mg is enough for almost all males to start feeling appetite suppression. and I've never seen non response to 10mg.

 

[mikeh1998]

His stats are 5'7" 220 lb by the way (BMI 34.5).

My friend titrated up to 10 mg/week of Tirzepatide and now weighs 205 lb (-15). He looks the same though.

I guess it takes 10 mg for it to "start working" for him. To be honest I expected him to lose more by now and be closer to 190.

 

[Ghoul]

You still see the occasional hyperresponder have it rough at 2.5mg, but generally, if one feels absolutely nothing, my advice has been to titrate 2.5mg the following week. Once you feel *anything*, stay at the same dose for at least 2 weeks before deciding to titrate up.

And of course, no harm at staying at a given dose for as long as it's bringing you closer to goal weight.

 

[runitback]

You still see the occasional hyperresponder have it rough at 2.5mg, but generally, if one feels absolutely nothing, my advice has been to titrate 2.5mg the following week. Once you feel *anything*, stay at the same dose for at least 2 weeks before deciding to titrate up.

And of course, no harm at staying at a given dose for as long as it's bringing you closer to goal weight.

Next week will be Week 4 of 5mg , I am now thinking of upping it to 7.5mg

 

[Ghoul]

Next week will be Week 4 of 5mg , I am now thinking of upping it to 7.5mg

I wouldn't hesitate.