Primo as AI and when to get labs

I will never pretend to understand this estrogen shit it makes no God damn sense.

Steroid experts be like.... "don't ever use an AI blindly, always go off of bloodwork. It's not a guessing game, you can't go off of feels for this kind of stuff it's serious business :mad:"

Then someone posts about how their E2 levels are high and the response will be "well it doesn't matter, how do you feel though? I feel best with my levels 3x the normal range, it just works for me :)"
 
I will never pretend to understand this estrogen shit it makes no God damn sense.

Steroid experts be like.... "don't ever use an AI blindly, always go off of bloodwork. It's not a guessing game, you can't go off of feels for this kind of stuff it's serious business :mad:"

Then someone posts about how their E2 levels are high and the response will be "well it doesn't matter, how do you feel though? I feel best with my levels 3x the normal range, it just works for me :)"
They are different schools of thought about how to manage estrogen
 
They are different schools of thought about how to manage estrogen
Sure. I genuinely don't get why we can't just go off of numbers though.

If other biomarkers come out super high we don't question if it's OK or not they get told to lower the dose or cycle off before real permanent damage can start taking place.

With estrogen there's so many people in the school of thought which is just "do what feels right :)" it's practically newb gaslighting.

Common interaction on any steroid forum... someone posts about suspected E2 issue -> gets called a dumbass for not getting a blood test -> posts blood test -> well just cause the blood test says ___ doesn't mean you actually need an AI, for instance personally _________
 
I ran 1:1 for a while until I got lean and discovered my E2 was pretty low. Since the. 2:1 seems fine. There’s a lot of individual variation, though. One of the metabolites of primo is an AI, but the rate at which one metabolizes varies according to genetics. The rate at which one aromatics varies according to leanness and also genetics.

So, do the bloodwork.
 
My aromatase activity seems pretty high I assume. However, I dont experience any sides from that, neither bloat or anything. If I go higher than 300mg TE the E2 affects me mentally, but not in any other aspect.

If it is too low libido gets crushed.

After 6-8 weeks of Primo TE/Primo E ratio 1:1 my E2 was cut by half and if I go higher on Primo than test, after a few weeks I start feeling my tendons and joints getting pretty "rusty". And my libido declines.

If all is adjusted properly for "well being" purposes, my libido is a burden with Primo and my tendons and joints are totally fine.

Guess this is highly individual, therefore bloodwork is essential to adjust it to yourself if you ask me.

Just my personal experience, no claim of absolute truth since this is highly subjective based on my own experience.
 
IMG_2272.webpResult are in. The three data points for me.
300mg Test no AI E 75
500/400 Test/Deca no AI E 122
500/400/400 Test/Deca/Primo no AI E 25

Primo definitely doing its thing. Going to retest E in a couple weeks because I had only bumped up from 300mg primo to 400mg a couple weeks before labs. Also want to test prolactin having issues finishing again, seems to happen whenever I run deca over 200mg.

HDL did take a hit and tested out of range for the first time came in at 33. Going to work some healthy fats into my diet see if that helps.
 
I get blood work in 6 days (the 4 week mark) to find out how much my E2 has been lowered from 127 on 200 Test-C and 400 Primo. My skin is still a little oily but my knees are starting to ache. lol I do aromatize a shit ton. I got to the 127 mark in 4 weeks (from 30) with 150 Test-C and 300iu HCG EOD.

If my E2 is in the toilet, I will bump the Test-C to 300 drop the Primo to 200 and add 200 Mast-E and recheck in 4 weeks. The joys of trying new compounds and seeing how your body reacts.
The results are in. My E2 has been lowered to 19 from 127. Going to bump up the Test to 300 or 400mg/week and retest in 4-5 weeks.
 
Hmm. I guess E2 doesn’t explain the oily skin.,
I can say for sure that since starting primo and getting E down my oil production is down. I’ve always been a heavy oil producer on gear or not. Acne was getting pretty bad on my chest and stomach. Have not had any new acne form in the last 4 weeks and some of the cystic nodules that have been lingering for a while now are starting to shrink and heal.
 
The results are in. My E2 has been lowered to 19 from 127. Going to bump up the Test to 300 or 400mg/week and retest in 4-5 weeks.
On you hcg injections do you do oil one day hcg next day? I do 250iu eod on days I’m not injecting oil. So on lab day I held off on injecting oil till after lab draw but I did do my hcg the day before. We are both running 400mg primo your running lower test I’m running higher test. But are E values are close I’m wondering if the E results are from the hcg injection. My joints are still aching even though E tested in range. Going to pull E labs again in a week but might skip my hcg and see if the E is any lower.
 
I can say for sure that since starting primo and getting E down my oil production is down. I’ve always been a heavy oil producer on gear or not. Acne was getting pretty bad on my chest and stomach. Have not had any new acne form in the last 4 weeks and some of the cystic nodules that have been lingering for a while now are starting to shrink and heal.
Primo dried everything out. Dry skin. Dry achy joints. Even my hair seemed drier/frizzier. Low E2 is no fun.
 
On you hcg injections do you do oil one day hcg next day? I do 250iu eod on days I’m not injecting oil. So on lab day I held off on injecting oil till after lab draw but I did do my hcg the day before. We are both running 400mg primo your running lower test I’m running higher test. But are E values are close I’m wondering if the E results are from the hcg injection. My joints are still aching even though E tested in range. Going to pull E labs again in a week but might skip my hcg and see if the E is any lower.
I do 300iu eod. I do not take anything on blood work days. I did see another member stated he also got oily skin from primo.
I personally noticed not much with Primo apart from a dryer look and a bit more oily skin at 250 and above
 
Threw primo into the stack a couple months ago started at 200mg been at 40omg for the past two weeks. Do I need to run 400mg for 5 weeks before getting labs to allow full saturation. Mainly looking to check E levels not sure if the AI effect requires saturation to get a true value. Elbows shoulder and neck are starting to ache.

Current stack
500/400/400/6iu Test/Deca/Primo/gh.
Going to be bumping the GH up to 8-10iu in a day or two.

I feel crashed e2 from first couple of injections, not even weeks
 
Threw primo into the stack a couple months ago started at 200mg been at 40omg for the past two weeks. Do I need to run 400mg for 5 weeks before getting labs to allow full saturation. Mainly looking to check E levels not sure if the AI effect requires saturation to get a true value. Elbows shoulder and neck are starting to ache.

Current stack
500/400/400/6iu Test/Deca/Primo/gh.
Going to be bumping the GH up to 8-10iu in a day or two.
In all sincerity, stacking three steroids has never yielded significantly better results for me compared to a higher dose of Testosterone combined with Primo or Equipoise, alongside ample HGH. With just two compounds, everything appears to function far more efficiently.

Testosterone remains the most effective muscle builder, while Primo and EQ serve primarily to slightly mitigate the need for aromatase inhibitors. The more test I used the better I felt the more I grew.

Ultimately, I would incorporate both—a modest dose of AI along with Primo or
EQ.
 
In all sincerity, stacking three steroids has never yielded significantly better results for me compared to a higher dose of Testosterone combined with Primo or Equipoise, alongside ample HGH. With just two compounds, everything appears to function far more efficiently.

Testosterone remains the most effective muscle builder, while Primo and EQ serve primarily to slightly mitigate the need for aromatase inhibitors. The more test I used the better I felt the more I grew.

Ultimately, I would incorporate both—a modest dose of AI along with Primo or
EQ.

Was my plan for my cut this summer, never ran high doses of test or anything before (<350mg) and using Primo as an AI, titrating it up to dry out even more and maybe add an oral for a few weeks (Var or Winny, but due to health reasons I tend to use Var again).

Wanna give it a try. However, even during injury recovery I noticed 150mg of NPP along with TRT and a slight dose of Primo to miligate E2 issues and maintain libido worked way better to grow for me.

Currently evaluating risk/benefit ratio of GH regarding cardiovascular risks instead of going higher on AAS and keeping them as low as needed in addition to GH.

Based on what my research on EQ was, Id rather prefer Primo and secondly Masteron.

Based on my knowledge, I dont know if it is more healthy to use Primo/EQ/Mast to prevent E2 issues (I feel pretty bad mentally on higher levels of TE) instead of an AI (Exemestane would be my choice). And run TE only.

But 150mg NPP + TRT (150-175mg TE weekly) was way more potent than 350mg of TE alone for me personally.
 
Was my plan for my cut this summer, never ran high doses of test or anything before (<350mg) and using Primo as an AI, titrating it up to dry out even more and maybe add an oral for a few weeks (Var or Winny, but due to health reasons I tend to use Var again).

Wanna give it a try. However, even during injury recovery I noticed 150mg of NPP along with TRT and a slight dose of Primo to miligate E2 issues and maintain libido worked way better to grow for me.

Currently evaluating risk/benefit ratio of GH regarding cardiovascular risks instead of going higher on AAS and keeping them as low as needed in addition to GH.

Based on what my research on EQ was, Id rather prefer Primo and secondly Masteron.

Based on my knowledge, I dont know if it is more healthy to use Primo/EQ/Mast to prevent E2 issues (I feel pretty bad mentally on higher levels of TE) instead of an AI (Exemestane would be my choice). And run TE only.

But 150mg NPP + TRT (150-175mg TE weekly) was way more potent than 350mg of TE alone for me personally.
You saw more potent, did you also feel better?
 
I'm on TRT now (140 Test C) but plan to run an old man cycle of 300 Test C with 100 Primo weekly (with Var pre-workout) pinned E3D for 10 weeks starting in April. At my age (and winter powerlifting bodyfat of 20-21%) 300 Test C raises my E2 to around 80 which means I'm holding more water that wanted/needed. I've never tried Primo so hoping I can avoid the AI (I usually use 250mcg of anastrozole on pin days which brings my E2 down to 40's)
300mg/100mg is a great starting point to figure out how primo will affect you.

Last year was the first time I tried primo.
Started at 200mg/100mg test to primo. Felt great. TT 920 E2 29.
Ran a cycle and got leaner.
Back on cruise at 200mg/100mg and joints started hurting.
Lowered primo to 80mg and ran with 200mg/80mg. Felt ok. TT 800 E2 24.
Dropped primo again and raised test. 250mg/90ish mg. Feel great again.
 
300mg/100mg is a great starting point to figure out how primo will affect you.

Last year was the first time I tried primo.
Started at 200mg/100mg test to primo. Felt great. TT 920 E2 29.
Ran a cycle and got leaner.
Back on cruise at 200mg/100mg and joints started hurting.
Lowered primo to 80mg and ran with 200mg/80mg. Felt ok. TT 800 E2 24.
Dropped primo again and raised test. 250mg/90ish mg. Feel great again.
Thanks brother. Great data. I will let you know how it goes. I think 3:1 is a great starting point for me just because I'm a hyper-responder to everything. May have to adjust....
 
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