Qingdao Sigma Chemical Co., Ltd (International, US, EU, Canada and Australia domestic

[readalot]

Please don't discourage him. We need someone to confirm for UGL HGH users what's already well established for pharma HGH patients.

No way. Genuinely asking.

 

[glpfun]

There are two sigmas, there is math sigma which is summation and standard deviation depending on casing and pop culture sigma which is some male crybaby thing I don’t pay attention to it because it reeks of red pill.

 

[LGOP528]

There are two sigmas, there is math sigma which is summation and standard deviation depending on casing and pop culture sigma which is some male crybaby thing I don’t pay attention to it because it reeks of red pill.

It depends on the subject. For example, lower case sigma also represents stress in strength of materials.

Now the upper case sigma used for summation, is used in math so standard across all subjects.

 

[Trailmixed]

Don't mix them. It's a marathon, not a sprint for the most noticeable results, 6 months. Results most similar to low dose GH, for anti aging rather than bodybuilder results. Lower risks than GH and should be sustainable indefinately with very minor, if any sides. We know there are daily users of Egrifta 10 years+, under medical care, without anything troubling in the data.

Easier to manage as well because of its indirect effect and physiological levels, pretty much any time of day is fine, as long as it's consistant,

Tesa also seems to result in ongoing higher levels of GH after use is stopped, fwiw.

Given the already high rate of immunogenicity with the pharma Tesa, this, perhaps more than any other peptide should be filtered IMO.

Good to know, thank you. Do you have a trusted/good resource on how to filter appropriately? I saw your links on the types of filters to use/website to purchase from, just didnt know proper technique.

 

[glpfun]

So taking 90 iu a day has to be due to immunogenic response but recombinant gh is supposed to have minimal immunogenic response. Maybe they were taking the pituitary derived gh from like 30 years ago?

 

[ZyzzReincarnate]

So taking 90 iu a day has to be due to immunogenic response but recombinant gh is supposed to have minimal immunogenic response. Maybe they were taking the pituitary derived gh from like 30 years ago?

Why do you like Mangos so much?

 

[Ghoul]

So taking 90 iu a day has to be due to immunogenic response but recombinant gh is supposed to have minimal immunogenic response. Maybe they were taking the pituitary derived gh from like 30 years ago?

No. Immunogenicity is primarily driven by aggregates. While pituitary GH was certainly prone to aggregation, its prevented in pharma rHGH and other peptide/protein therapeutics through very careful manufacturing that typically involves a very long process of trial and error, a very carefully formulated excipient recipe to prevent aggregation that takes a dedicated team to develop, very carefully chosen container materials since even the mineral content of glass or stopper rubber ingredients can induce aggregation, and finally cold chain handling with sensors to ensure it's not exposed to conditions that accelerate aggregation.

You know, just like UGL peptides are produced.

 

[glpfun]

Why do you like Mangos so much?

In the 90s a guy named Gary Zill started a mango breeding program to make more interesting varieties of mangos. This led to many interesting varieties such as pina colada, coconut cream, orange sherbet, guava, lemon zest, the list goes on. These varieties actually have tasting notes of the things they are named after, for example the pina colada mango when less ripe has a more pineapple taste and when more ripe has a coconut taste. IMO it has the most diverse taste across varieties out of any other fruit. Dragonfruit is another one I’m kind of obsessive about, most people have a bad experience with it buying from stores where it is always underripe and doesn’t ripen off the vine, but it is also a very diverse fruit in taste and physical characteristics.

 

[glpfun]

No. Immunogenicity is primarily driven by aggregates. While pituitary GH was certainly prone to aggregation, its prevented in pharma rHGH and other peptide/protein therapeutics through very careful manufacturing that typically involves a very long process of trial and error, a very carefully formulated excipient recipe to prevent aggregation that takes a dedicated team to develop, very carefully chosen container materials since even the mineral content of glass or stopper rubber ingredients can induce aggregation, and finally cold chain handling with sensors to ensure it's not exposed to conditions that accelerate aggregation.

You know, just like UGL peptides are produced.

I make my peptides in a wooden bucket

 

[Ghoul]

I make my peptides in a wooden bucket

Probobly better results injecting that than the recent "Shred Mix" ( @Dirthand ) vial of cancer causing food dye.

 

[mok4315]

It's always been the dive bar of Meso:

You have a guy giving a speech like a Roman Senator on some random topic in one corner of the room, half a dozen drunks are puking on his shoes, and fistfights break out randomly on a regular basis.

But it's really just about the cheap booze.

Man it’s been a few years since I’ve been in a good bar fight. I knew there was a reason I liked this place.

 

[CryAboutIt]

the fact that this was posted by someone called "CryAboutIt" is just delicious

No delicious is a meatball.

 

[Petarosus188]

As some clowns will tell you, I'm just a guy with google and secretly holding a major investment in filter manufacturers.

I asked ChatGPT (the one in my head) to sum up what it (me) would do if it (me) were in your shoes, and going down the path you've chosen.

Let me add you have an opportunity to also contribute to the community's body of knowledge in a significant way, as there's no "Office of Underground Lab Peptide Safety" pumping out the research a lot of knuckle draggers insist is required to recognize the risk of anything.

They look at pharma clinical trials and say "No immunogenicity problem there, so my UGL peptide is perfectly safe, idiot!"

That's the equivalent of saying Ford demonstrates a new car model can sustain a 40 MPH collision with 0% fatalities, so this $50 Temu GoKart is equally safe.

So in your shoes:

1: Get a baseline GH Antibody Test.

You can't self order it (too little demand), but if you go to a place like UltaLabTests and ask if they can arrange it for you, I think there's a good chance they'll add it to their "menu" of choices, and at a good discount below the standard ~$200.

2. Start filtering, per dose, just before administration. Aggregates take time to develop, the closer to administration the filtering the less time the trash UGL GH formula will have to recreate more aggregates.

This is the equivalent of changing brands. Given you haven't seen response go to zero, I strongly suspect as soon as the immune stimulating factors are reduced, aggregates and impurities. antibodies will drop, and efficacy will increase.

After a 1-3 months check Antibody levels again. If they're lower, you know you're moving in the right direction and should start lowering the dose to compensate for increased efficacy.

It's rare we see such a clear "loss of efficacy" situation, most of the time it's "feels" reports of members claiming bunk gear, that it worked in the past but this batch isn't working, yet tests show the GH is fine.

That's where the common denominator simian mind on Meso loses interest in trying to establish why (despite the fact this happens with pharma, which is why an anti- immunogenicity protocol and GH antibody tests exist). They take a break, or try another brand or switches to pharma, insists the new brand or pharma is the only way to go, never really digging into why HGH that tests good stopped being effective.

Finally, if you take my advice and get a GH antibody test, which I want to emphasize would be groundbreaking in the UGL community, request the lab provide whatever *raw data* is available. I can't find it at the moment, but I've read a report that said an adult GH non responder (in adults with GH deficiency they look at IGF and not growth like children), didn't show a positive result on the GH antibody test, but in the raw data there were antibodies of another type, not normally considered relevant, that were high. Once those were reduced (with a break and switching brands), HGH treatment efficacy was restored for that patient.

*here's the Quest link to the GH Antibody test with the codes you'll need to get someone to order it for you. I believe they're universal.

Quest Diagnostics: Test Directory

testdirectory.questdiagnostics.com

Dude I thought GH antibodies test Is expensive as fuck.
Also i read paperwork inside genotropins it actually says in small percentage of patients GH antibodies Develop early and in high amounts so huge doses Are needed. I believe even our insurance companies are taking it into account.
So one Guy on a fórum is expected percentage.
What type of filters you recommend to filter our aggregates but not GH molecules?

 

[Ghoul]

Dude I thought GH antibodies test Is expensive as fuck.

 

[millcityuhh]

QSC gh that I had a Stock off.....was best GH i had....

I placed my order a little bit past Christmas. Ended up getting my order on like the 11th on January. I think my pack was within some of the last packs sent out. It sucks that they legit just left after I finally got a taste for their shit. Everyone else using sigma Audley now?

 

[CryAboutIt]

This ain’t Amazon bro, it’s hard to forget what we’re doing is illegal, and one day you will take a loss, not every package is gonna come thru, is this the one? I hope not cause I got money out there too but if it does come to it, fuck it, I knew what I signed up for

I get it. I know what I signed up for too. But coming here and whining like a cunt about 2024 being a non-profitable…like we should feel sorry for a fucking drug dealer…he can lick my asshole. Take my money and GTFO. Don’t pop in here and give some sorry ass bullshit story. He’s like the guy that steals your wallet and helps you look for it. Ain’t my first rodeo bud. And I certainly ain’t crying about being out a g-wiz. I just want what’s mine. And you don’t got it then don’t show your fucking face or you’ll get bashed every time you surface without my money.

 

[WhyteOwl]

I get it. I know what I signed up for too. But coming here and whining like a cunt about 2024 being a non-profitable…like we should feel sorry for a fucking drug dealer…he can lick my asshole. Take my money and GTFO. Don’t pop in here and give some sorry ass bullshit story. He’s like the guy that steals your wallet and helps you look for it. Ain’t my first rodeo bud. And I certainly ain’t crying about being out a g-wiz. I just want what’s mine. And you don’t got it then don’t show your fucking face or you’ll get bashed every time you surface without my money.

 

[BamaCrazy]

Fitomics LabCorp $65.21

Fitomics Quest offers a Growth Hormone test for $45, but it isn’t labeled Growth Hormone Antibodies l, just Growth Hormone (GH), so I’m not sure if it’s the same test.

 

[RintintinRedRocket]

In the 90s a guy named Gary Zill started a mango breeding program to make more interesting varieties of mangos. This led to many interesting varieties such as pina colada, coconut cream, orange sherbet, guava, lemon zest, the list goes on. These varieties actually have tasting notes of the things they are named after, for example the pina colada mango when less ripe has a more pineapple taste and when more ripe has a coconut taste. IMO it has the most diverse taste across varieties out of any other fruit. Dragonfruit is another one I’m kind of obsessive about, most people have a bad experience with it buying from stores where it is always underripe and doesn’t ripen off the vine, but it is also a very diverse fruit in taste and physical characteristics.

Any tips on selecting a suitable mango? Any thoughts on Thai mangoes versus South American varietals?

 

[Clover 0080]

For real, da fuck is a sigma?

I could be wrong but it was an old wooden ship used during the civil war era