Do you plan to blast in old age (40+)?

[egruberman]

ApoB results are in:

A1: 109
B: 100
B/A1 Ratio: 0.92

These numbers are high enough, that some concern is warranted. As mentioned, i would prefer to see ApoB <80mg/dL and a B/A1 ratio less than .7.

You could try all the lifestyle things to lower lipids, if you haven't already, or you could consider pharmaceutical intervention. If you want to avoid pharma, for now, it's probably best to get a calcium score. If I had these numbers and a zero result on a CT-CAC, I'd feel comfortable not using pharma.

 

[raminaro]

Nah definitely not for me. I'd rather stick with some regular supps stack. I would feel like making a very bad trade with the future.

 

[kaizoku]

These numbers are high enough, that some concern is warranted. As mentioned, i would prefer to see ApoB <80mg/dL and a B/A1 ratio less than .7.

You could try all the lifestyle things to lower lipids, if you haven't already, or you could consider pharmaceutical intervention. If you want to avoid pharma, for now, it's probably best to get a calcium score. If I had these numbers and a zero result on a CT-CAC, I'd feel comfortable not using pharma.

Thanks.

Calcium score is on the list of things to do once I can get in to a new doctor.

And I don’t mind a mix of pharma and lifestyle intervention.

For lifestyle:
My diet is pretty good, certainly not perfect, probably too many eggs and too much butter.

Definitely need more cardio, working on carving out more time for that.

 

[egruberman]

Thanks.

Calcium score is on the list of things to do once I can get in to a new doctor.

And I don’t mind a mix of pharma and lifestyle intervention.

For lifestyle:
My diet is pretty good, certainly not perfect, probably too many eggs and too much butter.

Definitely need more cardio, working on carving out more time for that.

Eggs are fine, the butter may not be, depends on your genetics.

Non-pharma, try citrus bergamot, psyllium husk, berberine, EPA and cardio 3-5 times per week for around 180 minutes or more of zone 2.

Pharma…. Low dose Rosuvastatin and ezetimibe. Maybe also bempedoic acid if you can get it cheaply.

 

[egruberman]

@Mememe why the random dislike for what I presume is non-controversial?

 

[kaizoku]

Eggs are fine, the butter may not be, depends on your genetics.

Non-pharma, try citrus bergamot, psyllium husk, berberine, EPA and cardio 3-5 times per week for around 180 minutes or more of zone 2.

Pharma…. Low dose Rosuvastatin and ezetimibe. Maybe also bempedoic acid if you can get it cheaply.

Taking citrus bergamot daily, and slowly building the zone 2 cardio up. Never really been a cardio guy other than HIIT and sprinting, carving out that extra time has been an adjustment.

I have Indian rosuvastatin, ezetimibe and bempedoic acid on hand. I will be asking my new PC provider when I can get in to one for US pharma scripts for all of these.

Already taking the ezetimibe based on your earlier recommendation of starting there because it’s least likely to cause side effects.

I know Peter Attia recommends aggressively attacking ApoB levels with rosuvastatin and bempedoic acid, with ezetimibe as a backup if the patient can’t tolerate the others.

Seeing my initial lipid results wasn’t alarming but seeing ApoB is eye-opening.

And to go along with the thread title…yes I still plan to blast in old age, but will be doing so with lipids under control.

 

[kaizoku]

@Mememe why the random dislike for what I presume is non-controversial?

@Mememe I was going to ask the same thing.

 

[egruberman]

Taking citrus bergamot daily, and slowly building the zone 2 cardio up. Never really been a cardio guy other than HIIT and sprinting, carving out that extra time has been an adjustment.

Yeah. It’s hard. I did so well for years waking up early and cycling for an hour before my family was up and about. Moved about 9 months ago and everything seemed to go awry.

I know Peter Attia recommends aggressively attacking ApoB levels with rosuvastatin and bempedoic acid, with ezetimibe as a backup if the patient can’t tolerate the others.

I don’t have a great rationale for how to approach the choice of just one or two of these compounds. They all have a different, complementary mechanism of action. If one can tolerate a
statin, its a good choice. Bempedoic acid is great, but can be expensive. Ezetimibe is benign, but also yields the least reduction of the three. For myself I have a non-zero calcium score ~40 something IIRC so mild. As a result I run all three.

 

[Theworm]

Get on repatha asap

 

[egruberman]

Get on repatha asap

Not a bad strategy if one can swing it. It'll move the needle further than anything else.

 

[AlexDavis43]

Thanks.

Calcium score is on the list of things to do once I can get in to a new doctor.

And I don’t mind a mix of pharma and lifestyle intervention.

For lifestyle:
My diet is pretty good, certainly not perfect, probably too many eggs and too much butter.

Definitely need more cardio, working on carving out more time for that.

Eggs are fine, the butter may not be, depends on your genetics.

Non-pharma, try citrus bergamot, psyllium husk, berberine, EPA and cardio 3-5 times per week for around 180 minutes or more of zone 2.

Pharma…. Low dose Rosuvastatin and ezetimibe. Maybe also bempedoic acid if you can get it cheaply.

 

[egruberman]

View attachment 319215

And?

 

[Token777]

I’m 50, found my trt dose at around 200mg twice weekly of Enanthate in 2 pins, feel much better on 300mg a week in 3 pins and mitigates all my low T symptoms.

Just went to 350mg TE and added deca for joint health atm and just gonna titrate up slowly over weeks and check everything, hoping to clear the sides many get on it.

Run full sports panel labs every 10 weeks or after a change and check BP most days.

I’m hoping to experiment with other compounds and go up even though I’m 50, I ain’t gonna stop unless health takes a hit.

 

[egruberman]

Just went to 350mg TE and added deca for joint health atm and just gonna titrate up slowly over weeks and check everything, hoping to clear the sides many get on it.

I ran deca at low doses for a short while for the same reason. Probably the only compound I’ve tried so far that hits me with side effects. The mental sides were unpleasant and it took a long time to clear.

Not saying it won’t work for you but NPP clears much more quickly. I found my joint health improved when I stopped lifting like an idiot.

 

[kaizoku]

For all the back and forth about butter, I doubt that the small amount that I eat (maybe one tablespoon a few days a week) is the reason for my ApoB being far from ideal.

I do very little cardio and just came off (6 weeks prior to bloodwork) a very long low dose tren e cycle with var at the beginning and end.

With that said, I am going to aggressively pursue significantly improving my lipids overall through added cardio and pharma.

Added 5mg rosuvastatin and 180mg bempedoic acid to my nightly supplement stack starting tonight and will be getting bloodwork again in 6-8 weeks depending on my work schedule and also finding a new doc.

 

[Lions_Fan]

Late 40s here. I just run test-e or test-c. 250mg twice a week. I honestly still feel like I'm in my 30s. Around 45, I did feel like my body was getting older and maybe breaking down but I think it was just mid life crisis. Feel much better now. Been running the same dose for almost a decade.

 

[whispersauce]

I am 49 soon 50 and cruise year round on 500mg Test E and 150mg Deca for joints. Sometimes go to 750mg a week Test E with Anavar and the Deca.
Not been on long but feels good even though I have injuries which limit some movements

 

[NewGuy756]

40 is old age?

What year is this 5000BC?

 

[NewGuy756]

Late 40s here. I just run test-e or test-c. 250mg twice a week. I honestly still feel like I'm in my 30s. Around 45, I did feel like my body was getting older and maybe breaking down but I think it was just mid life crisis. Feel much better now. Been running the same dose for almost a decade.

you run 500mg test a week all year round for years on end!?

 

[AlexDavis43]

you run 500mg test a week all year round for years on end!?

Not uncommon around here.

To say "perma-blasting" is taboo so everything is TRT or TRT+ nowadays. Even if it's 200+ mg/wk.