Giant Semaglutide Thread (and other GLP-1 / GIP agonists)

[Doodle]

Wanted to create a thread where everyone can post their experiences with different sourced Semaglutide.

Who are you using?
Pharma vs non?
Dosage?
How long have you been taking it?
What are your thoughts?
Have you lost weight?
Side effects?
Oral vs injection?
Tests?

 

[SnowyMiami]

Wow that's awesome news since I just got the TR30 from them. I was using Semaglutide, then I had to switch to QSC Tirzepatide. And it never seemed to work. While I didn't gain tons of weight, I did gain some, and it just seemed to not blunt hunger at all. It was nowhere near Semaglutide. I was asking whether my particular product sucked or whether Tirzepatide just wasn't for me. So I am very curious how TR30 will be. I am thrilled to hear what you just wrote.

Thats the problem with UGL garbage. You never know if the compound doesn't work for you or if it's made wrong.

 

[setters]

Thats the problem with UGL garbage. You never know if the compound doesn't work for you or if it's made wrong.

I mean, not really. If it’s a vetted vendor and it’s tested, it’s going to work.

 

[BigDadd7]

Thats the problem with UGL garbage. You never know if the compound doesn't work for you or if it's made wrong.

Try not to buy UGL garbage. There are plenty of vendors with tested gear. Do some diligence before purchasing.

 

[RATGYM]

Does anyone else get nasty burps. I can deal with the burps. Helping out a friend of mine and she is going off about the burps LOL

Yes they are common. I switched between non-pharma labs recently due to supply constraints and they are not as evident (though are there) which has me curious about efficacy but that’s another conversation. Definitely the burps. Sometimes lightheadedness and a bit of nausea as well.

 

[RATGYM]

Wanted to create a thread where everyone can post their experiences with different sourced Semaglutide.

Who are you using?
Pharma vs non?
Dosage?
How long have you been taking it?
What are your thoughts?
Have you lost weight?
Side effects?
Oral vs injection?
Tests?

Getting feedback on 2 different GLP1 labs is prohibited am I correct?

 

[VDV_Pablo]

Hey guys, who can recommend me a good source for tirz or sema in eu? bought stuff from godtropin, been 3 weeks on it, nothing... seems like a bunk.

 

[eryximachus]

Hey guys, who can recommend me a good source for tirz or sema in eu? bought stuff from godtropin, been 3 weeks on it, nothing... seems like a bunk.

I ordered some reta from Optihgh. Their products have been good to me in the past. But after 8 weeks if I don't notice anything I'll send in a vial to be tested.

 

[Ghoul]

Hey guys, who can recommend me a good source for tirz or sema in eu? bought stuff from godtropin, been 3 weeks on it, nothing... seems like a bunk.

Which GLP? What dose? Plenty of "non-responders" out there who need much more than usual to "feel it".

 

[VDV_Pablo]

Which GLP? What dose? Plenty of "non-responders" out there who need much more than usual to "feel it".

Tirz, 2.5mg/week as i read that is enough to stay on. I wonder, should i go to 5mg a week to "feel it" ? but my apetite is the same, weight is the same.

 

[Ghoul]

Tirz, 2.5mg/week as i read that is enough to stay on. I wonder, should i go to 5mg a week to "feel it" ? but my apetite is the same, weight is the same.

I didn't feel any effect from pharma Tirz at all until I hit 10mg,

If you don't want to lose any weight, it's beneficial to use the highest dose you can that doesn't suppress your appetite. All the non weight loss benefits are increased at higher doses. Better insulin sensitivity, lower inflammation, more liver fat clearance and healing.

 

[VDV_Pablo]

I didn't feel any effect from pharma Tirz at all until I hit 10mg,

If you don't want to lose any weight, it's most beneficial to use the highest dose you can that doesn't suppress your appetite. All the non weight loss benefit are increased at higher doses. Better insulin sensitivity, lower inflammation, more liver fat clearance and healing.

I took this for weight loss and apetite suppresion. Planning on taking test on top of that with t3 in upcoming months, as im back to the gym after injury.

 

[Jesintn]

I took this for weight loss and apetite suppresion. Planning on taking test on top of that with t3 in upcoming months, as im back to the gym after injury.

Glps increased thyroid output 33% in rats. I had extreme anxiety oin tirz , t3, mucuna pruiriens

 

[Ghoul]

Glps increased thyroid output 33% in rats. I had extreme anxiety oin tirz , t3, mucuna pruiriens

GLPs have no direct effect on the thyroid.

Losing weight lowers thyroid levels.

 

[12o3j129dq]

I have been taking Sema for a long time, 2.5 mg weekly. My appetite usually returns after three to four days. How high would you set the next dose? I have been taking 2.5 mg for well over three months.

 

[Ghoul]

I have been taking Sema for a long time, 2.5 mg weekly. My appetite usually returns after three to four days. How high would you set the next dose? I have been taking 2.5 mg for well over three months.

In the 7.2mg trials Novo Nordisk went from 2.4 directly to 7.2. That said, since normal titration is 1 to 1.7 to 2.4, going to 3.5 seems like a reasonable titration that should induce further weight loss without nearly as much of a chance of significant sides. If you feel no difference after 2 weeks you could bump 4.5.

Sema's effects aren't linear. Increases from higher doses have an increasingly smaller impact as doses rise, probably because glp receptors start to saturate and there's nothing more to gain.

 

[Deadpool99]

Located in Central Europe. Sourcing my Metformin from Online Pharmacy already, just costs me 20€ + Shipping extra all the time, annoying but it works

Hey, if you wouldn’t mind sharing the pharmacy. I’m moving to the US and where I’m from metformin is OTC, and finding pharma grade metformin without a prescription is nesr impossible in the US. I completely understand if you don’t want to “spoon feed me”.

 

[Ghoul]

Hey, if you wouldn’t mind sharing the pharmacy. I’m moving to the US and where I’m from metformin is OTC, and finding pharma grade metformin without a prescription is nesr impossible in the US. I completely understand if you don’t want to “spoon feed me”.

Getting a prescription in the US takes 5 minutes on the phone, and it's dirt cheap at the pharmacy once you do.

 

[TheBeast1]

Has anyone experienced orthostatic hypotension when running reta?

I'm taking 10mg a week for maintenance and I am having a bear of a time. When I stand up after laying down or sitting my vision blacks temporarily. It's worse at night and one time I found myself on my ass.

What seems to help has been drastically increasing the amount of table salt I add to my food but I still have moments where it happens. Problem with this is my food is almost too salty.

I'm thinking about supplementing salt of all things now before I go to bed.

 

[Ghoul]

Has anyone experienced orthostatic hypotension when running reta?

I'm taking 10mg a week for maintenance and I am having a bear of a time. When I stand up after laying down or sitting my vision blacks temporarily. It's worse at night and one time I found myself on my ass.

What seems to help has been drastically increasing the amount of table salt I add to my food but I still have moments where it happens. Problem with this is my food is almost too salty.

I'm thinking about supplementing salt of all things now before I go to bed.

Have you checked your BP around these events? Do you have low BP normally?

Hypotension isn't really a thing with GLP's, but hypoglycemia can mimic the effects, though that's pretty rare too unless the GLP is being used with other things that interact with glucose control.

What other drugs are you taking?

 

[bananafeet]

Big thanks to @readalot for his comments on the danger of cagrilinitide.

Just searched it up and looked into the fibrilis. Crazy stuff