MESO-Rx
Anabolic Steroids
i'm only on 10 mg per day, no side effects to speak of,
Correction on the "fasted insulin " 80 was my fasted glucose , my frikin fasted insulin was 2.2 ughhh im hoping this is just because i have "new medications " and have quit taking Metformin, so maybe that high fasted insulin was like a rebound and it will settle back down , ima retest in a few weeks , but its really got me trippin, i personally think thats its a skewed test, but will definitely keep vlose eye on this,,
I agree on extended high levels causing some sort of problem, whether thats insulin resistance or acromegaly, etc,, but not for EVERYONE, some can and some can't handle high doses of hgh ,,rHGH glucose intolerance is based on growth hormone's direct anti-insulin effect, not IGF. At 2iu it's rarely a problem for anyone. In fact, high IGF improves insulin sensitivity.
The only thing unusual in this case was the doctor's failure to do his job, monitor IGF and reduce rHGH to keep IGF in the physiological range. The doctor didn't, and the expected outcome resulted, acromegaly. It's a rare example because it's rare for doctors to make this mistake for years until this happens. If GH replacement therapy routinely doubled IGF rHGH induced acromegaly wouldn't be rare.
Most modern cases of acromegaly happen in otherwise healthy people, late in life, who develop a pituitary tumor without obvious symptoms. No one checks IGF until the patient asks their doc why they've started looking like an ape.
It's easy to dismiss cases not involving a "healthy" subject. And since no researcher will ever get approval to double someone's IGF with rHGH for years to see what happens it's safe to say that "proof" with a perfectly healthy person will never appear. But we can come close.
In this example. A 40 year old develops brain cancer. The surgery to remove that tumor inadvertently damages his pituitary, so he's no longer making enough GH. He's put on 3iu / day. No one ever checks his IGF. Almost the same amount of time as our guy above, 6 years later, he wants to know why he's two shoe sizes larger and gotten so ugly. IGF 800+. Higher than the first guy, but since he's younger this is again double the upper limit of normal for his age.
Iatrogenic Acromegaly | BES2002 | 21st Joint Meeting of the British Endocrine Societies | Endocrine Abstracts
www.endocrine-abstracts.org
There's nothing to suggest either of these men were any more prone to developing acromegaly from 2x normal IGF than anyone else, or that somehow, a "healthy" person with the same 2x IGF would be immune to the same problem.
Illicit rHGH users are unlikely to admit use or publish a formal diagnosis, ahem:
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Jawbones don't widen from normal aging.
Bottom line:
The mantra up to now for rHGH use has been "as much as you can afford and tolerate". Clearly price was a limiting factor. Five days on two off was common, to "stretch" precious rHGH.
That's all changed.
Very long term continuous rHGH use as a PED or anti-aging compound has been a rarity, exclusively for pro athletes and the very wealthy, up until the recent massive price drops. It's clear many of us are buying quantities intending to stay on GH for the long term. We have very little to guide safe choices. I think these two documented cases give us some sense of what "crossing the line" looks like. 2x upper IGF limit for more than a couple years seems like it can be reasonably inferred as getting into the danger zone. We also know that up to 1.3x the upper limit of normal IGF seems to be tolerated by doctors, and no cases of acromegaly have been reported in patients after many years at that level. The "many years" IGF safety threshold most likely lies somewhere between 1.3x and below 2x, with the risk growing the closer you get to 2x.
All this has convinced me that staying at 1.3x age adjusted upper limit of normal IGF or below is a reasonable way to keep long term risks low while still benefitting from ongoing GH use.
My fasting insulin showed early insulin resistance after 1.5 years at 5iu despite my fasting glucose and a1c being absolutely fine the entire time. Shocked the fuck outta me. Washed out hgh completely and doubled down on diet. I’ve returned to low dose hgh 2.4iu rest days 2.8iu lift days because it’s so good for my depression and anxiety, but I stepped up my semaglutide dose to 1mg to balance it. I’m testing it every 2-3 months now because it scared me pretty bad.
its got me so baffled, how can all other glucose numbers be good and this one is off,? i am just going to recheck in a few months, make a few adjustments and test again, pretty strange, i hope its not "the beginning of the end",, lol
I do not think I would bother.
Soo theoretically if I had bought 900$ worth of hgh so for me 250 days worth of 4ius… whattt then bc honestly ik im taking the
route one day if that may be in 2-4 yrs who knows but im very educated on the science behind it and genuinely love training, dieting, and the life style i currently only take bullshit peptides but haven’t touched any gear for obvious reasons (and ofc I have a coach I’m not just ducking around with my shit haha also blood work, I have perfect bloodwork and natural t is at 680 so not horrible)
i would ride this out "as natural" for as long as your hormones allow, you are in a decent spot with igf1, as well as tt, (could be higher) but as long as your feeling good, making progress, then why mess with it, "if its not broke, don't fix it" ,,Soo theoretically if I had bought 900$ worth of hgh so for me 250 days worth of 4ius… whattt then bc honestly ik im taking the
Well yes yes I do agree for the “natural” part but seeing as almost a thousand dollars of gh is coming to my door in let’s say four days I’m quite certain that the gh is gonna do more benefit then harm if I take it now compared to waiting??? Who knows how long that’s the thing I won’t know and what am I supposed to only run it once I first start my first cycle but what if then isn’t the “right” time much to think about
Why did you buy it? Put it in your freezer and it’s good for years. I wouldn’t fuck with your nice natty numbers personally. Your igf1 is naturally higher than mine when I do 3iu. You’re not going to get much out of this with 4iu beyond fucking with your insulin sensitivity, prolactin, and thyroid. Feasibly 4iu would be less than you’re producing right now.
Ya that’s not how it works though…
What are you talking about? Nothing I told you was incorrect
U could even chat gpt what u said and it would tell u that indeed is not correct 4ius is not equivalent to 295 and im sorry if ur using shit to get higher igf1 and u can’t but it’s either ur using fake/bad shit or ur not doing something else right
ChatGPT doesn’t know if you’re a good or shitty responder to hgh lol. There are people running 5iu+ who don’t have your natty igf1. Being dismissive of people trying to help and blindly listening to ai is how your dumbass is going to hurt yourself. Why even come ask questions if this is going to be your childish response?U could even chat gpt what u said and it would tell u that indeed is not correct 4ius is not equivalent to 295 and im sorry if ur using shit to get higher igf1 and u can’t but it’s either ur using fake/bad shit or ur not doing something else right
Brother u think im using chat gpt as my source? No dog im using fucking pro coaches, pros that talk about ts openly, them literally running 4 ius on their own plan. Ur brain washed if u think that just bc im young idk shit lol and I asked a question to see if I got any actual smart educated responses that instead of having someone call me a “dumbass” because I disagree with them for numerous reasons bc u can’t give me any actual proof that 4ius is gonna somehow “make my igf worse” when for one hgh isn’t just all about igf and two it literally isn’t 4ius is that start of physiological levels and 295 is not physiological
Says the grown man with a tit pic as his pfp bc he’s just a little poor incel, it’s okay bro it gets easier just go out side and try to socialize. But fr idk what world u live on where u can’t read the part where I just said im not using chat gpt for my source of info for anything u dumb fuck. I quite literally said I get my info from top pros and real coaches, I also myself HAVE A COACH I’m not also listening to the guy that probably buys the shittiest gh he can find and ends up with shitty igf1 levels, also for one HGH IS NOT JUST ABOUT THE IGF1 BENEFITS
