MESO-Rx
Anabolic Steroids
Giant Semaglutide Thread (and other GLP-1 / GIP agonists)
- Thread starter Doodle
- Start date
give it time jesus christ. so many people think they're like a magic pill that supresses appetite. I got no appetite suppresion until my 3rd week of tirz back when I started.
These drugs are a long term thing, people fuckin use them as they would use DNP or Clen Jesus christ
Last edited:
phenominal34
Banned
Are you ok ? Do you feel test when you inject it ? Is it not working ?
I feel how pain as it gets old hearing “oh it’s not working, I feel nothing” especially when it’s posted all over the forum and everywhere on the internet that Reta does have the powerful appetite suppression as Sema or Tirz.
bananafeet
Member
Please re-read my original post.
I am feeling something from Retatrutide. It's jacking up my heart rate and giving me skin sensitivity.
Am I supposed to believe that these effects will diminish with time and the appetite suppression will magically appear?
My experience with drugs is that the more you take the more of an effect you get. So if I'm getting non of the effects I want and all the effects I dont... What's the point
And to answer your question yes I do feel something when I inject testosterone around day 3.
try switching to Tirzepatide if you don't like Retatrutide
Ghoul
Member
Not sure why the hostility is coming at you..
You've used Sema and Tirz. You're familiar with GLPs.
And your experience aligns with many others.
Most doses seem under 4mg. Often 2 or less. Maybe the effective appetite suppression comes in at the higher doses. The trials titrate subjects up to 8 and 12, which are rarely seen being used around here.
If not, one wonders how they'll market this as a replacement for Tirz.
bananafeet
Member
To be fair it took a month on sema at 0.25mg to notice a massive difference. However I remember almost immediately that food tasted "off". Like I couldn't get the same enjoyment out of it. It almost immediately cured my binge eating, where I'd just lose interest in eating a lot of food.
On a Friday night we had fish and chips and I tried to have a few chips (French fries?). However they tasted like day old chips, and the oil felt and tasted disgusting. I didn't know what was happening at the time.
Increasing doses of semaglutide to the max clinical dose would have my stomach on lockdown for 12 hours where I could only get a decent meal in once. If I pushed it I'd vomit or just couldn't physically fit the food in.
Then with tirzepatide I felt immediately fatigued, my stomach still worked but I had no "drive" to eat. It was like the reward circuits were fried. I also noticed on Tirz I was tired as fuck. I had to use Modafinil to keep me functional.
So yeah for Retatrutide it's early days, but it's not looking promising. At least for this batch.
The main confounding issues is everyone hyping this drug.
So with my limited experience so far if I had to run a maintenance drug long term it would be sema followed by tirzepatide.
Maybe I'll stick with the Retatrutide for a bit longer. But if I keep having to add in 1mg of semaglutide here and there to keep my appetite at bay I don't see the point.
Reminds me of how hyped Primo is/was.
I have a sneaking suspicion Retatrutide is interrupting my sleep as well.
Photon
Member
RHR will remain elevated.
Skin sensitivity will fade, but comes back when you increase the dose.
Appetite suppression will not get stronger, it will in fact feel weaker over time, maybe cause you get used to it? (idk)
I only recently noticed another effect from Tirz. Before I started it, I used to drink a lot of Cherry Diet Pepsi, especially during cutting phases. Without even realizing it, I haven’t touched it in over a year now - plain water feels like enough. It’s honestly surprising how this medication works. So far, I haven’t noticed a single downside, except for maybe a bit of fatigue for a day or two after the shot.
dinfar1337
New Member
i have quit my nicotine addiction when i was on tirz.
i've tried so many times off glp and i was so horny after new nicotine i never lasted a week.
on tirz i quit nicotine and knew the same day i never needed it again. its like it completely killed the addicition. its interesting how these drugs work
Ghoul
Member
There are multiple potential causes of tirz fatigue, but it's usually only while calorie deficit/weight loss is ongoing.
Once on a stable maintainance dose fatigue isn't usually reported.
What you describe sounds more like mild hypoglycemia, since it's right after the injection when it's most likely to happen.
May want to check your glucose, or consider what else you're using that could be driving glucose down. Normally this gets adapted to and stops within the first few months.
It’s probably due to low blood sugar. My recent labs usually show glucose between 58 and 75 mg/dL. The only time it was higher, around 95, was because I took 4iu of HGH before the test.
Also, with Tirz, I sometimes forget to eat, especially on busy days when I’m running around all day. Then if I stand up quickly, I feel a bit lightheaded.
Right now I’m on 250mg of Test, 2.5iu of HGH per week, and 15mg of Tirz. I feel great. Blood pressure stays around 100 to 110 over 60 to 70, heart rate is 60 to 70. Everything feels solid.
That’s awesome and I believe you. I’m actually helping a friend get back in shape too and “made” him start Tirz as well. He quit smoking, gave up alcohol, and dropped from 130 kg to 78 kg in under two years. It honestly feels like a miracle.
Ghoul
Member
I've been on it for a couple years now, and fatigue eventually stopped, so hang in there.
The end point of all GLPs is really a stable maintenance dose that feels like nothing, while it stays quietly in the background doing its magic.
Almost all organs, from your eyes to capillaries in your toes have cells with GLP receptors, and in every case they do something positive for your health when activated.
Ghoul
Member
For those suffering from any condition related to excess consumption, or know someone who is, keep this in mind and consider pointing them in this direction, regardless of weight:
"Anti-consumption agents: Tirzepatide and semaglutide for treating obesity-related diseases and addictions, and improving life expectancy"
"Anti-consumption agents: Tirzepatide and semaglutide for treating obesity-related diseases and addictions, and improving life expectancy"
dinfar1337
New Member
i also tend to believe new users oversupress themselves way too much. have to find a balance between good dosage and normal living
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