MESO-Rx
Anabolic Steroids
Giant Semaglutide Thread (and other GLP-1 / GIP agonists)
- Thread starter Doodle
- Start date
bananafeet
Member
Retatrutide quick and dirty review:
Day 1: 1mg
Day 3: 1mg
Day 6: 2mg
Day 7: 1mg
Total dosing: between 6-6.8mg (I drained remainder of vial to cross reference).
Positives:
1. Tons of energy on day 8 compared to other GLP1-RAs
2. Can still eat fine, no reflux
3. Somehow helps with edema. Don't ask me how
Negatives:
1. Appetite suppression is nuanced. When you eat it's hard to stop, you're ravenous. But you can go without eating.
2. Increases heart rate and contractility. Ie your heart beats harder and pounds in your chest. I had to increase dosing of metoprolol.
3. Absolutely wrecks sleep. Due to heart rate issues and increased excitability. Possible night time hypoglycemia.
4. Zero stomach slowing. Food speeds through the stomach.
5. Random attacks of lightheadedness or dizziness. I don't know if this is me not needing to adjust my meds or not, but I've never had it happen.
Usage cases:
1. People with good appetite control who want a bit of an aid and a visceral fat burner (GCCR).
2. Those without heart issues or arrhythmias.
I still think semaglutide is probably one of the best for the following reasons (at least for maintenance):
1. Slows down the stomach and causes reflux if you eat poorly (you can eat like shit on reta and Tirz)
2. Great mental effects in terms of food noise
3. Good blood sugar control
4. Long lasting effects (up to 1.5 weeks in my experience)
5. Cheap
Where tirzepatide wins:
1. Even better blood glucose control
2. More fatigue however
3. More flexibility with food choices
4. Less harsh on the stomach
I am not very bullish on Retatrutide after my experience with it.
I'll let the brain's trust know how I go with mazdutide. I don't see the point of taking more Retatrutide, I don't think the results will improve that much for me.
Day 1: 1mg
Day 3: 1mg
Day 6: 2mg
Day 7: 1mg
Total dosing: between 6-6.8mg (I drained remainder of vial to cross reference).
Positives:
1. Tons of energy on day 8 compared to other GLP1-RAs
2. Can still eat fine, no reflux
3. Somehow helps with edema. Don't ask me how
Negatives:
1. Appetite suppression is nuanced. When you eat it's hard to stop, you're ravenous. But you can go without eating.
2. Increases heart rate and contractility. Ie your heart beats harder and pounds in your chest. I had to increase dosing of metoprolol.
3. Absolutely wrecks sleep. Due to heart rate issues and increased excitability. Possible night time hypoglycemia.
4. Zero stomach slowing. Food speeds through the stomach.
5. Random attacks of lightheadedness or dizziness. I don't know if this is me not needing to adjust my meds or not, but I've never had it happen.
Usage cases:
1. People with good appetite control who want a bit of an aid and a visceral fat burner (GCCR).
2. Those without heart issues or arrhythmias.
I still think semaglutide is probably one of the best for the following reasons (at least for maintenance):
1. Slows down the stomach and causes reflux if you eat poorly (you can eat like shit on reta and Tirz)
2. Great mental effects in terms of food noise
3. Good blood sugar control
4. Long lasting effects (up to 1.5 weeks in my experience)
5. Cheap
Where tirzepatide wins:
1. Even better blood glucose control
2. More fatigue however
3. More flexibility with food choices
4. Less harsh on the stomach
I am not very bullish on Retatrutide after my experience with it.
I'll let the brain's trust know how I go with mazdutide. I don't see the point of taking more Retatrutide, I don't think the results will improve that much for me.
bananafeet
Member
Maybe the edema reduction is increased renal profusion mediated through an increased heart rate? Who knows. Interesting tho
Musmadar
Member
I my case, Tirz cut the need for eating anything sweet.... absolutely cut it like it made me sick just to look at cookies or any other sweets ... It lasted for aprox 6 months...after that it's very normal, I eat some sweets but very little.
I was NEVER big on sweets until I tried Retatrutide; it made me CRAVE anything and everything sweet. Strange.
Eddie.
Member
You have 1 week using it and already came to conclusions? I didn’t felt anything until 3-4 weeks after I went from low dose to moderate dose. You’re way to impatient.
dinfar1337
New Member
if this guy was running tirz or semaglutide with that dosing schedule his asshole would have been burning right now
bananafeet
Member
I followed the normal dosing schedule for semaglutide and tirzepatide. Me no scare.
Edit:
I have injection records for every shot I've done. I can dig them out if you want.
I am starting to think either reta is overhyped or I've been injecting something else.
Last edited:
bananafeet
Member
I didn't actually intent to. I wanted to follow the original progression. Like 2mg a week for a month, then 4 mg.
But unlike the other GLP1-RAs I felt nothing. Even with semaglutide at 0.25mg I still get appetite suppression.
So yeah it just happened.
dinfar1337
New Member
reta is basically the bodybuilding glp.
it dosent affect appetite at all i feel like and it provides the benefits of lower bloodsugar, and other health benefits glps provide. its super powerful combination for people with normal appetite that just wanna use hgh or bulk and stay insulin sensitive.
retarutride can be used for both bulking and cutting, where as sema and tirze side effects is so strong u can barely use it for cutting
Liter O' Test
Member
you type all this shit up as if you have a clue yet you dont even kno that reta is less appetite supressing than the other glps.
goodluck with your wreckless dosing of experimental glps
bananafeet
Member
Never claimed I had a clue... Just sharing my experiences bro
It's easy to sit on the sidelines and brag about how much you know. Why don't you put something useful together to help.
Just an idea
Liter O' Test
Member
sidelines? your contribution is a meaningless wall of text, there are HUNDREDS of pages of threads on this topic and your 8 days and googled information is worthless.
i dont have to put together anything useful, all the information is out there, you should read it instead of moving on to your 4th GLP
"just an idea
bananafeet
Member
Point taken. It's actually my 3rd GLP1-RA. I will start my 4th next week.
Do you want some anecdotal reports on mazdutide when I try it because I've searched and there are zero on this site.
Or do you think it can be all discovered with a simple "Google Search". Because personally speaking the anecdotal reports I've found on this site have been the most informative and helpful.
I mean you seem to speak for everyone on this board, so let me know how we are gonna do this boss.
dinfar1337
New Member
Liter O' Test
Member
there are zero reports because its a bad compound and people are smart enough to stick things that are FDA approved or commonly used
if you had some common sense and did more than some superficial google searches, you would understand that these arent just fat burners to play around with.
why do you even want to use mazdutide? just because the chinese are selling it?
bananafeet
Member
Retatrutide isn't approved... Mazdutide has less data behind it but seems promising due to:
1. Less side effects reported
2. Less impact on heart rate
I've been following it for a while, here is the latest report on it:
It's a GCCR and GLP1-RA. It has more glucagon activation compared to Retatrutide which favours GIP.
I don't think it's fair to defend Retatrutide in one hand and critise Mazdutide in the next breath.
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