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Can't say I agree of his thoughts on tren and understanding hepatotoxicity.
Overall he is a nice guy
He’s a (online) friend of mine and started MENT along with high dose test and Deca. And he uses anastrozole rather than Aromasin. He wound up with a complex mess of high estrogen and prolactin symptoms, which he thought was from low estrogen.
A little cheat sheet with MENT - if using any significant amount along test, any estrogen problems are almost certainly going to be from excess rather than inadequate estrogen. 7α-me-e2 fulfills the biology for estradiol, so measured LC/MS estradiol can be zero and you’ll be just fine if you feel good.
True low estrogen you will have zero energy, lifting a 5lb dumbbell seems difficult and painful, and the Johnson is useful for urination only. Zero interest in the opposite sex, hot or not.
You cannot start MENT at say 5mg/day (which is what I typically recommend for previous AAS users) and double the dose every couple days if things seem okay. It’s like increasing test from 200 > 400 > 800 > 1600 mg over a short period of time without an AI. If 5mg/day is okay after a week go to 6-7.5mg at most, not 10mg!
I find tren + MENT a perfect match. The potent estrogen offsets many of the tren toxicities particularly in the brain, at least if sleep is adequate (quetiapine is amazing for this).
Nandrolone is a hard no with MENT for most people; it barely aromatizes but is well known for upregulation and/or sensitizing the ER, hence why adding it to even just test commonly results in gyno & ED even if e2 levels are basically stable. With MENT is much worse, with an estrogen floating around that is 4x as potent at trans activation of the ER.
Tren and MENT are complimentary, just need to watch for combined progestogenic effects ie upregulation of prolactin receptors (prolactin itself is almost never elevated in blood work). I find it reasonable to control this with a little caber ie 0.25mg twice a week; if more is needed then time to cut back the doses of one or both.