L Carnitine has no bio availability, waste of money.
MESO-Rx
Anabolic Steroids
L-carnitine and Retatrutide for Health Purposes
- Thread starter ganciodestro
- Start date
TorrentialGlacier
New Member
Injected L Carnitine has no bioavailability?
ganciodestro
Member
I think he means oral carnitine
Nope not for fat loss same as NAD+.another schill
Waste of money
Last edited:
facinghardships
New Member
Source for both those claims?
Cross referencing multiple resources on the internet also discussing with high-level coaches for bodybuilding and my own personal experience you send me your address I'll mail you the bottle that I have in it doesn't do anything you send me 200 bucks I'll send you my kit of NAD Plus doesn't do anything either except on the initial injection. Like everyone else here I wanted it to work but it doesn't. But to each his own.
Turkeybuilder
Member
I personally noticed increased fatigue reduction when I started daily 600mg L carnitine
Felt like I could just do more and more sets
adrenalytic
Member
This isn't a thing. One molecule binds per AR, no freak-off binding. I think you mean the upregulation of AR density. And yes, there is some evidence that L-Carnitine L-Tartrate can upregulate androgen receptor density and sensitivity.
Androgenic responses to resistance exercise: effects of feeding and L-carnitine - PubMed
Neolancer80
New Member
Binding is reversible and ligands, like DHT, have slower off-rates than test does, so it’s not just one molecule and done. The one small human study on L-carnitine L-tartrate showed a modest increase at best in AR content, but no change in binding affinity or ‘sensitivity.’ Bigger trials since then haven’t confirmed any effect on AR sensitivity, only recovery benefits if anything. So the claim that L-carnitine upregulates receptor density and sensitivity is overstated to say the very least
bigdaddyandfriends
Member
No appetite suppression from 18mg/wk reta? Over 4mg/wk I can barely eat and get nasty sulfur burps and hiccup episodes that last for hours - sometimes requiring gabapentin and tizanidine to stop. Mine is from SSA (RIP).
I previously used Tirz and found mg per mg, appetite suppression was similar, maybe minimally more with Tirz.
Luckily at about 3.5mg/wk it blunts my appetite to where I get hungry but eat less each meal, and still get the metabolic benefits. I use trestolone and more recently added boldenone, both of which greatly increase appetite, so it really helps keep my food intake in check.
I wasn't aware L-carnitine needs carbs to work. I usually take it fasted or before I eat any carbs (which I usually limit to pre-intra-post workout). Its main purpose is to shuttle fatty acids into mitochondria for energy production, or at least that is what I thought... need to do some more reading I suppose. I take 600mg/day subQ divided into two 0.5cc shots, as I avoid injecting larger volumes of water into muscle as it's much more likely to cause an infection compared to oil.
I previously used Tirz and found mg per mg, appetite suppression was similar, maybe minimally more with Tirz.
Luckily at about 3.5mg/wk it blunts my appetite to where I get hungry but eat less each meal, and still get the metabolic benefits. I use trestolone and more recently added boldenone, both of which greatly increase appetite, so it really helps keep my food intake in check.
I wasn't aware L-carnitine needs carbs to work. I usually take it fasted or before I eat any carbs (which I usually limit to pre-intra-post workout). Its main purpose is to shuttle fatty acids into mitochondria for energy production, or at least that is what I thought... need to do some more reading I suppose. I take 600mg/day subQ divided into two 0.5cc shots, as I avoid injecting larger volumes of water into muscle as it's much more likely to cause an infection compared to oil.
Photon
Member
If you follow clinical trials, dose escalation is every 4w, which brings you to 12mg @ month 5. Yea i don't get suppression on 18mg, maybe its the 1g of EQ lol. If anything I'm having to control my eating. Vials from SSA too.
Carnitine needs insulin, so i pin it during either lunch or dinner.
Neolancer80
New Member
Have you checked your igf1 levels
Photon
Member
bigdaddyandfriends
Member
Interesting
I may need to adjust my L-carn timing, although I do take 300mg preworkout and use an intraworkout drink w/ carbs. The other 300mg I take am w/ low carbs during the day, so not much insulin.
I have not needed to escalate my dose at all. I feel like the almost mandatory dose escalation in clinics (Sema and Tirz obviously) is very Sackler-like… some may need escalation, but not a doubling every 4 weeks. In the past I’ve escalated about 10% when needed… when I tried to go to 5mg Reta I had issues. Currently doing 0.5mg/day which seems to working well.
I started EQ a month ago but only 30mg/day (and nearly half if that is the heavy undeclynate ester. Basically an experiment on how I tolerate it and to see if it affects my E2 - primo does not to any significant degree.
The clinical trials are every 4 weeks but that seems a stupid way of doing things. Seems like a money grab more than anything. I lost 70+ lbs on tirz and never got past 5mg. But I know plenty of people on 15mg a week who have lost half that. THE best protocol for any GLP is lowest dose for the longest amount possible until it doesn’t work anymore. And I don’t mean it doesn’t make you want to stuff your face. If you’re using a GLP-1 as injectable willpower you’re doomed to fail
bigdaddyandfriends
Member
Very true
For those who need more appetite suppression, cagrilitide is supposed to work well. Been on Reta over a year now, started at 3mg/wk and now at 4.5mg/wk… more than that I can barely eat. And that’s on a little trestolone and EQ which both drive appetite.
I’m the same. 2-4mg a week Reta. Not so much for weight loss, but as a maintenance as it helps keep stuff in range that AAS generally fucks. And as you say keeps some of the EQ horse hunger at bay as I’m also on EQ.
ChemBB
Member
Out of curiosity, are you planning on sort of indefinitely increasing the dose?
Do you think it's even doing anything for you at this point?
Photon
Member
Yes, I take it because it doesn't give suppression. If i wanted suppression I would have done tirz or sema.
If you don’t want suppression, but the other benefits, why not stay low dose?
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