Wuhan Wansheng Biotechnology Co., Ltd. (USA, International)

[AlexDavis43]

Yeah I've seen the whole "teaspoon in a bathtub" explanation before and pun intended, it doesn't seem to hold water. Let's look at the numbers.

Six day halflife. Let's take a 1mg dose as an example. That means I take 1mg Monday, .5 mg remains in my system the following Sunday. So each day represents approximately 1/12th of that 1mg diminished. After the halflife is reached it takes 5 halflives for the original dose to leave your system.

So if you want 1mg of Reta to remain in your system as your effective dose, you take .5 mg Monday, Wednesday and Friday. This builds the concentration of Reta in your system week after week, since each microdose keeps your serum ahead of the rate of depreciation. The bathtub slowly fills.

This allows for each person to reach their own personalized minimum effective dose, and they are either going to hit slight side effects (i.e. ease off on the dose) or hunger signaling (i.e. increase *one* of the microdoses). Either way the bathtub keeps filling, over a longer period of time, and many people may never need to reach the supposed effective thresholds of 8+ mg that the trials suggest have the greatest impact. Less drug burden. Personalized effectiveness. Less money spent.

Or you can just crank that shit once a week because Eli Lilly said so...

Alright Dr Trev.......ha ,

Stable blood plasma levels are just that no matter how you get there! Whether that be by injecting once a week , 3 times or 7!
It's the journey to those stable levels , that we all get to choose, no right or wrong!
If you can handle bigger peaks then hit once a week. wanna smooth the journey out hit 3 ,5 , 7.
Many roads lead to Damascus my friend. Oh & Dr Trev is a tool!

These are fairly complicated drugs

One theory as to why they're so effective at once weekly dosing is that it causes downregulation of some receptors that take time to recover

A little hunger returning on day 5 or 6 (right before your next dose) might be part of how it works so effectively in clinical trials

 

[BigNate78]

Maybe with Reta. I wouldn’t know. I just bought some for the first time but i saving it for my cut after my next bulk that I’m starting in January. I can say with Sema and Tirz it wasn’t until I got to the middle doses that the weight really started to drop. I’ve read the RETA is whole different animal though. I can’t wait to try it.

Yeah im about to drop does to 1mg when i get back from thanksgiving to do a bulk yet keep some of the benifits of reta while doing it.
Even at 3mg its been amazing and im not try8ng hard to cut neither but its definitely helped in so many ways

 

[canes]

These clowns have no idea I take .5 mg a week and have 8-11 % body fat and lost 18 lbs in a month. Yet they taking 15 mg a week and wasting and feeling like shit with the sides lmao. I feel incredible too. And my heart isn’t afib anymore so if ppl say you don’t get good results on .5 they’re literally retarded and have no clue how Reta truly works & these ppl saying take 10 mg a week just wanna sell bottles and make money.

How long have you been taking it? I've been on a glp for 3 years. Have a feeling my dosing experience has been different than yours.

 

[BigNate78]

These are fairly complicated drugs

One theory as to why they're so effective at once weekly dosing is that it causes downregulation of some receptors that take time to recover

A little hunger returning on day 5 or 6 (right before your next dose) might be part of how it works so effectively in clinical trials

Reta doesnt have as aggressive suppression as the other two buy its def there. On tirz I couldnt even think about fokd without getting nauseous. Reta im able to get food in thats needed but you get that full feeling early and aticks around. I dont want to lift and starve lol you never keep any gains. They way it works on gluclose is insane! Cant wait to see even at low dose how it does with the insulin sensitivity and added igf during a bulk

 

[BigNate78]

How long have you been taking it? I've been on a glp for 3 years. Have a feeling my dosing experience has been different than yours.

Reta is a whole other level than tirz or semi. So tjeres a big difference

 

[BigNate78]

How long have you been taking it? I've been on a glp for 3 years. Have a feeling my dosing experience has been different than yours.

It will because you're not him amd hes not you. Everyome need to remember that when finding THEIR sweetspot

 

[nogainz]

A little hunger returning on day 5 or 6 (right before your next dose) might be part of how it works so effectively in clinical trials

3x a week for the past 12 weeks. Down 22 lbs. I dunno. I'd rather not have the hunger rebound every week, so whatever magic is helping me avoid that I'll take it.

 

[Raww]

Why approved as once-weekly (not daily):​

Weekly dosing is chosen because superior long-term adherence/persistence (50–60% at 1 year vs. 20–35% for daily) outweighs the slightly flatter PK profile of daily dosing. Efficacy is essentially identical or slightly better with weekly at the same total exposure.

Why someone would still choose daily (or split doses):​

To dramatically reduce nausea/vomiting — daily micro-dosing gives an even flatter concentration curve and much lower Cmax, so peak-related GI side effects often disappear while keeping the same weekly exposure and full efficacy. Convenience is sacrificed for tolerability.

 

[trtbuilder]

2-3 mg a week of reta destroys my appetite. Cant imagine going over that.

Even at 12mg Reta doesn't kill my appetite. Everyone responds differently and over time smaller doses become less and less effective.

 

[trtbuilder]

too much gear rage alil more

Bro, you got owned by Tracy for pretending to be some Canadian Vendor. Keep talking shit, pathological liar. Most likely you're a fat fuck.

 

[RockyP]

Even at 12mg Reta doesn't kill my appetite. Everyone responds differently and over time smaller doses become less and less effective.

Very true - some folks get the usual GLP appetite crushing form Reta, some get zero.

I just increased from 2 mg twice weekly to 2.5 mg twice weekly. 24 hours after the first dosage of 2.5 mg and my appetite is curbed quite a bit. That said I switched from Tirz to Reta specifically because even on a cut I could not eat enough on Tirz. I was able to get up to 3000-3200 cals daily for a few months on the 4 mg Reta but decided to bump it to keep things moving. I don't think I will go above 8 mg prior to taking a break from it.

 

[47Ronin]

Very true - some folks get the usual GLP appetite crushing form Reta, some get zero.

I just increased from 2 mg twice weekly to 2.5 mg twice weekly. 24 hours after the first dosage of 2.5 mg and my appetite is curbed quite a bit. That said I switched from Tirz to Reta specifically because even on a cut I could not eat enough on Tirz. I was able to get up to 3000-3200 cals daily for a few months on the 4 mg Reta but decided to bump it to keep things moving. I don't think I will go above 8 mg prior to taking a break from it.

lol it’s def hard to eat on TIrz which is great if you’re trying to cut and drop pounds but lean bulking not so much. I do find that THC helps with maintaining somewhat of an appetite.

Reta doesnt have as aggressive suppression as the other two buy its def there. On tirz I couldnt even think about fokd without getting nauseous. Reta im able to get food in thats needed but you get that full feeling early and aticks around. I dont want to lift and starve lol you never keep any gains. The way it works on gluclose is insane! Cant wait to see even at low dose how it does with the insulin sensitivity and added igf during a bulk

Rethinking my plan lol. I thought RETA would make it even harder to eat then TIRZ. If what you’re saying are the facts; well the I’m going to do the same thing during my bulk. Ill throw in the TIRZ during the last few weeks of my cut to quiet the hunger pains but the RETa I’ll take at low dose during my bulking cycle. Im excited

Gonna start with a little dbol for the first month. test, EQ, tren, mast, RETA through out the whole cycle and I’ll end with Winny and some

 

[RockyP]

lol it’s def hard to eat on TIrz which is great if you’re trying to cut and drop pounds but lean bulking not so much. I do find that THC helps with maintaining somewhat of an appetite.

What I have not tried, and Idk if i will since I prefer Reta but if I do ever go back to tirz, is combining boldenone with tirz for the appetite bump.

 

[BigNate78]

lol it’s def hard to eat on TIrz which is great if you’re trying to cut and drop pounds but lean bulking not so much. I do find that THC helps with maintaining somewhat of an appetite.

Rethinking my plan lol. I thought RETA would make it even harder to eat then TIRZ. If what you’re saying are the facts; well the I’m going to do the same thing during my bulk. Ill throw in the TIRZ during the last few weeks of my cut to quiet the hunger pains but the RETa I’ll take at low dose during my bulking cycle. Im excited

Gonna start with a little dbol for the first month. test, EQ, tren, mast, RETA through out the whole cycle and I’ll end with Winny

Yeah its why a lot of lifters are turning to it along with the way it helps with insulin sensitivity and steady gluclose curves

 

[47Ronin]

What I have not tried, and Idk if i will since I prefer Reta but if I do ever go back to tirz, is combining boldenone with tirz for the appetite bump.

EQ works to. I’ve done that as well along with THC on my last cycle. 1st time adding any kind GLP-1. I’m leaner than I’ve ever been but def lost some muscle along the way. All good though. I will gain it right back when I bulk up.

 

[47Ronin]

Yeah its why a lot of lifters are turning to it along with the way it helps with insulin sensitivity and steady gluclose curves

100% giving it a try bro!

 

[canes]

It will because you're not him amd hes not you. Everyome need to remember that when finding THEIR sweetspot

That was my point haha

 

[setters]

These are fairly complicated drugs

One theory as to why they're so effective at once weekly dosing is that it causes downregulation of some receptors that take time to recover

A little hunger returning on day 5 or 6 (right before your next dose) might be part of how it works so effectively in clinical trials

Most likely it works in spite of, not because of, the low serum levels on day 5-6. And there is no evidence of down-regulation of receptors, given that people are still losing weight 1.5 years into the clinical trials at the same dose.

 

[AlexDavis43]

Most likely it works in spite of, not because of, the low serum levels on day 5-6. And there is no evidence of down-regulation of receptors, given that people are still losing weight 1.5 years into the clinical trials at the same dose.

Dan Drucker and Jim Johnson have commented on receptor downregulation being part of why once weekly dosing was so effective

I mean, you do you, if your protocol is working well for you, go for it

 

[slarsen7810]

Ordered with Cavan on October 30th 2025. Tracking received November 4th 2025. Touchdown November 19th 2025. Illinois USA. Everything accounted for and packaged well.

Edit - Ordered from China warehouse.