Massive_1975
New Member
Yes zopiclone. My reship package has been in customs since last week and that leads me to think they are looking for that product.Think it refers to zopiclone.. otherwise curious on the meaning as well
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BP_6
Member
I wasn't aware the 3 combo was on the list. The one I have seen though is 40mg Tela/10mg Cil/6.25 Chlo. I am not 100% sure on the Chlor though, I think there is also a 12.5. Someone can verify which one this is.
Maybe I'm crazy but I don't see the third drug as a stand alone
BP_6
Member
The chlor is basically a mild diuretic like HCTZ but longer lasting and better overall generally for BP management. In the US, it comes stand alone 25 and 50mg only. However, in India I have seen it as low as 6.25mg as above.
Healing Pharma appears to have a 40/10/12.5 and a 40/10/6.25. I am sure someone or PCT will chime in who knows which one this is. Not a dramatic difference as in both cases it is quite a low dose, but I too would like to know.
adversi
Member
BP_6
Member
Thank you so much sir! So it is the 6.25 version. I will have to switch to this. I have been cutting my 25mg tabs into 1/4 and it is a pain.
just some dude
Member
i do the first 2 + indapamide separately but awesome to see the convenience of a combo exists, kinda like a once a day multivitamin, the diuretic difference in question isn’t even drastic and $1.75 that’s a golden axe in terms of blood pressure.
BP_6
Member
Absolutely and remember, he now has 25% off all which is even better. Running the numbers, even with my insurance this is a much better deal overall and it is convenient in one pill.
bigdaddyandfriends
Member
Telmiheal Trio. Dosing is 40mg/10mg/6.25mg
Nearly perfect combo...one pill per day should suffice for 'cruise' or can increase to two per day for 'blast', or as needed to maximize BP lowering.
Some info re: diuretics...
ARBs like telmisartan and BBs like Nebivolol raise serum potassium, significantly so in a small % of people, and bodybuilders typically have high potassium intakes as meat is a rich source. Chlorthalidone and indapamide are thiazide-type, potassium-losing diuretics, both are a great choice add to an ARB regimen, and are also helpful in preventing kidney stone formation. Indapamide is more potent per mg and has less effect on lipids/glucose.
Loop diuretics ie Lasix/furoesmide, are potassium-losing as well but typically prescribed for those with pre-existing heart/kidney disease, while thiazide-type diuretics are typically prescribed for hypertension in those without heart/kidney disease.
MRAs like eflererone, finererone and spironolactone are potassium-sparing diuretics. Spiro also blocks the androgen receptor. They can cause or contribute to hyperkalemia when used with ARBs/BBs.
CCBs don't affect potassium. Cilnidipine is far better than any available in USA - for those who have high blood pressure with or without androgens, it is worth having a stockpile.
ACE inhibitors have the same end effect as ARBs, but act in the lungs via indirect mechanism rather than having a direct effect in the kidneys. They are obsolete with ARBs on the market, and should never be used or prescribed because of pulmonary side effects - cough and more importantly lung cancer development (independent of other risk factors). Despite plenty of articles about this going back about a decade, doctors for some reason still commonly prescribe them. They do not belong on the USA formulary with better/safer alternatives available.
bigdaddyandfriends
Member
That's my current regimen too. Basically bullet-proof blood pressure control, mine as okay even during a brief period when I went up to 10mg/kg of anabolics per week.
Indapamide may be slight advantages over chlorthalidone but they are very similar drugs at least in terms of effect.
bigdaddyandfriends
Member
Only things I've gotten confiscation letters for are Zopiclone and carisoprodol. They seem have it out for those two... each seized pack also had another drug I think would be much higher on their interest list, and neither time was it mentioned in the letter.
Thanks. I'm at 80/20 on the first two and still having BP as high as 159/80. Only on 250 test 4iu GH.
Can anyone clarify if the third drug is sold separately? I don't see it.
Photon
Member
The above guys are on Telm+Cilni and indapamide.
You might have resistant hypertension in which case you might want to consider a MRA.
Adding on to what @bigdaddyandfriends shared.
bigdaddyandfriends
Member
That’s high on those low doses of test/GH
Make sure you’re getting plenty of magnesium and vitamin E - I suggest supplementing at no less than 10mg/kg per day & 10iu/kg per day.
Also check your HCT and make sure it isn’t way out of range. If it is, donate once then look into adding Naringin + silymarin + taxifolin, and/or changing to a short ester. Stable levels from long esters are good for anabolism, not so much for HCT and Libido, where daily peak and troughs are better.
Telmisartan helps somewhat with HCT too.
Sicsemptyran
Member
Also consider higher potency drugs as you layer in 3rd/4th lines.
Azilsartan is the strongest ARB, you can add in one of the many diuretics, nebivolol for a 4th class (beta blockers).
I personally prefer using something like empagliflozin which has dramatic pro longevity effects, protecting the kidneys/heart/insulin sensitivity, while also lowering BP in a diuretic like fashion. Not as dramatic as a diuretic on the BP fromt though.
In your case, 3rd/4th layers are a good idea as well as figuring out why it’s that high in the first place. Did you have high BP previously?
Photon
Member
I'm not sure if nebivolol will do much but adding a SGLT2 is def a good idea. I'd pay close attention to potassium with all those meds in play..
Ghoul
Member
Manufactired by Bioaltus for Healing Pharma, if you’re curious:
third Party Pharma Manufacturer | Bioaltus Pharmaceuticals
Trusted rd party pharma manufacturer offering cGMP-certified contract manufacturing with advanced iMickro Nano tech across key therapies.
bioaltus.com
Sicsemptyran
Member
Given that he’s maxed out doses of 2 of the 4 major blood pressure classes, even if nebivolol gets him 5-7 systolic, it’s a win. Kind of in a kitchen sink situation at that point.
Adding in SGLT2, swap for a stronger ARB, figure out what the hell is causing that high of BP, kind of gotta do it all if you’re rocking those BP numbers with already a fairly high BP stack.
Vrjorp
Member
Be careful of the long af half life of the diuretic…
Not enough hydration/electrolyte balance means cramps for daysssss
Not enough hydration/electrolyte balance means cramps for daysssss
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