Wuhan Wansheng Biotechnology Co., Ltd. (USA, International)

[serge6647]

Any Canadians have issues with this postage thing or they g2g now ?

3 orders so far no complaints about 2-3 week delivery

 

[Photon]

I hate to ask but can you point me to the filters you’d use for this?

For 0.9 BA aqueous, either PES PVDF or PTFE will work.
It's just significantly quicker with PES.

There's pretty much zero resistance when you filter it.
it flows like tap water -- it is basically water with some b.a.

I get mine from Ks-Tek but Cobetter has them, but 100pc minimum.
I also like how Cobetter has pre-filter options for some of their filters.


For smaller quantities i think only .22um is available..unfortunately they all seem sold out lol. .22um is sufficient.

Tisch Scientific Filter Syringe .22μm PTFE 25mm - Sterile Individually

Tisch Scientific Filter Syringe 22μm Ptfe 25mm – Peptide Test Lab Supplies - Fast, accurate, and trusted.

peptidetest.com

PES Syringe Filter, 0.22um, 13mm, Luer Lock/Luer Slip, Sterile – Molecular Mischief

molecularmischief.com

 

[AllGoodThings]

I have limited experience with GH, only started it this May, but I've used two different vendors here for all that I have, the majority being from a domestic vendor known for his GH, the gold top variant. I also recently added some yellow tops (both white and silver sticker) from WWB. I reconed my first yellow top vial yesterday, and noticed it behaved differently from what I've experienced from the other vendors' GH I'm used to. Instead of it dissolving over the course of a minute or two, it essentially instantly dissolved into the Hospira, being clear and homogenous within 5 seconds or so. Drawing it into a 31g needle for injection, I also noticed I could pull it into the syringe way faster than other GH I'm used to. If I draw too fast with gold tops, something resembling a head of foam will accumulate at the top of the syringe. I generally try to go slow enough that this doesn't occur, but with the WWB yellow tops, you can pull back and create a bunch of suction and the GH actually flows faster than gold tops, and no matter how fast I go, zero foam or bubbles appear. As I'm relatively inexperienced with GH, I was hoping someone with more knowledge than me could comment on the relevance of this observation, if there is any.

@Ghoul
@OldGHGuy
@Photon

I don't know who the GH experts here are, so forgive me if I left you out

 

[Ghoul]

I have limited experience with GH, only started it this May, but I've used two different vendors here for all that I have, the majority being from a domestic vendor known for his GH, the gold top variant. I also recently added some yellow tops (both white and silver sticker) from WWB. I reconed my first yellow top vial yesterday, and noticed it behaved differently from what I've experienced from the other vendors' GH I'm used to. Instead of it dissolving over the course of a minute or two, it essentially instantly dissolved into the Hospira, being clear and homogenous within 5 seconds or so. Drawing it into a 31g needle for injection, I also noticed I could pull it into the syringe way faster than other GH I'm used to. If I draw too fast with gold tops, something resembling a head of foam will accumulate at the top of the syringe. I generally try to go slow enough that this doesn't occur, but with the WWB yellow tops, you can pull back and create a bunch of suction and the GH actually flows faster than gold tops, and no matter how fast I go, zero foam or bubbles appear. As I'm relatively inexperienced with GH, I was hoping someone with more knowledge than me could comment on the relevance of this observation, if there is any.

@Ghoul
@OldGHGuy
@Photon

I don't know who the GH experts here are, so forgive me if I left you out

The TLDR is that foaming is a negative quality indicator.

It’s impossible to say whether it’s a minor negative or major issue because there are a bunch of potential causes, but the bottom line is that it’s not something you want to see.

The cause can be a poor excipient “recipe”, the lyophilization process wasn’t done properly (a porous cake, or too much moisture left), or damaged rHGH (unfolded) from any number of causes (bad raw, or the vials were exposed to high heat.).

Whatever the cause, the foam itself damages rHGH.

This is because anywhere there’s an interface between rHGH and air, it unfolds exposing “sticky” parts that are usually protected within intact folded rHGH. These damaged rHGH molecules become the nuclei of aggregate formation. Like the first ice particle of a big chunk of hail. I won’t go into why aggregates are bad again, but they are.

Foam is really a mass of tiny bubbles, so the amount of this “interface” area in foam is huge. Much worse than a few bubbles.

Does this mean foaming ruins the vial? No. Probably the loss of a few percent of active GH. But it does mean aggregates are present and filtering is especially important after foamy reconstitution.

 

[nobu156]

For 0.9 BA aqueous, either PES PVDF or PTFE will work.
It's just significantly quicker with PES.

There's pretty much zero resistance when you filter it.
it flows like tap water -- it is basically water with some b.a.

I get mine from Ks-Tek but Cobetter has them, but 100pc minimum.
I also like how Cobetter has pre-filter options for some of their filters.
View attachment 370070

For smaller quantities i think only .22um is available..unfortunately they all seem sold out lol. .22um is sufficient.

Tisch Scientific Filter Syringe .22μm PTFE 25mm - Sterile Individually

Tisch Scientific Filter Syringe 22μm Ptfe 25mm – Peptide Test Lab Supplies - Fast, accurate, and trusted.

peptidetest.com

PES Syringe Filter, 0.22um, 13mm, Luer Lock/Luer Slip, Sterile – Molecular Mischief

molecularmischief.com

Thank you man, much appreciated

 

[Photon]

The TLDR is that foaming is a negative quality indicator.

It’s impossible to say whether it’s a minor negative or major issue because there are a bunch of potential causes, but the bottom line is that it’s not something you want to see.

The cause can be a poor excipient “recipe”, the lyophilization process wasn’t done properly (a porous cake, or too much moisture left), or damaged rHGH (unfolded) from any number of causes (bad raw, or the vials were exposed to high heat.).

Whatever the cause, the foam itself damages rHGH.

This is because anywhere there’s an interface between rHGH and air, it unfolds exposing “sticky” parts that are usually protected within intact folded rHGH. These damaged rHGH molecules become the nuclei of aggregate formation. Like the first ice particle of a big chunk of hail. I won’t go into why aggregates are bad again, but they are.

Foam is really a mass of tiny bubbles, so the amount of this “interface” area in foam is huge. Much worse than a few bubbles.

Does this mean foaming ruins the vial? No. Probably the loss of a few percent of active GH. But it does mean aggregates are present and filtering is especially important after foamy reconstitution.

I think he's talking about the air bubbles that form in the syringe when you draw from the recon'd vial, not when reconning the vial.

I get that too with Q's HGH if I draw really quick using a 31g. I assume it's just pressure from having to push the liquid through a small space (31g) really quick. If I use a thicker needle like a 29g, the air bubbles don't form.

I'm not entirely sure if there is any damage but I do draw a lot slower and that prevents the bubbles.

 

[lipzz17]

The TLDR is that foaming is a negative quality indicator.

It’s impossible to say whether it’s a minor negative or major issue because there are a bunch of potential causes, but the bottom line is that it’s not something you want to see.

The cause can be a poor excipient “recipe”, the lyophilization process wasn’t done properly (a porous cake, or too much moisture left), or damaged rHGH (unfolded) from any number of causes (bad raw, or the vials were exposed to high heat.).

Whatever the cause, the foam itself damages rHGH.

This is because anywhere there’s an interface between rHGH and air, it unfolds exposing “sticky” parts that are usually protected within intact folded rHGH. These damaged rHGH molecules become the nuclei of aggregate formation. Like the first ice particle of a big chunk of hail. I won’t go into why aggregates are bad again, but they are.

Foam is really a mass of tiny bubbles, so the amount of this “interface” area in foam is huge. Much worse than a few bubbles.

Does this mean foaming ruins the vial? No. Probably the loss of a few percent of active GH. But it does mean aggregates are present and filtering is especially important after foamy reconstitution.

Foaming is bad even if you mix without caution? I think every peptide will form foam if mixed directly by water no?

 

[Photon]

Foaming is bad even if you mix without caution? I think every peptide will form foam if mixed directly by water no?

If you dispense the bac water at a very slow rate while pointing the needle at the glass (so it drips slow into the peptide), there's usually close to no foam.

 

[RocketSurge0n]

Only problem with these cases is the need to want to fill all the slots

Hahaha yea that’s what I’m doing.

 

[lipzz17]

If you dispense the bac water at a very slow rate while pointing the needle at the glass (so it drips slow into the peptide), there's usually close to no foam.

Yeah i try but vacuum its annoying, its possible to kill the vacuum before putting Bac water ? Or it can damage the peptide

 

[RocketSurge0n]

Yeah i try but vacuum its annoying, its possible to kill the vacuum before putting Bac water ? Or it can damage the peptide

You can just throw a needle in and vent it.

 

[TeaSleep333]

I have limited experience with GH, only started it this May, but I've used two different vendors here for all that I have, the majority being from a domestic vendor known for his GH, the gold top variant. I also recently added some yellow tops (both white and silver sticker) from WWB. I reconed my first yellow top vial yesterday, and noticed it behaved differently from what I've experienced from the other vendors' GH I'm used to. Instead of it dissolving over the course of a minute or two, it essentially instantly dissolved into the Hospira, being clear and homogenous within 5 seconds or so. Drawing it into a 31g needle for injection, I also noticed I could pull it into the syringe way faster than other GH I'm used to. If I draw too fast with gold tops, something resembling a head of foam will accumulate at the top of the syringe. I generally try to go slow enough that this doesn't occur, but with the WWB yellow tops, you can pull back and create a bunch of suction and the GH actually flows faster than gold tops, and no matter how fast I go, zero foam or bubbles appear. As I'm relatively inexperienced with GH, I was hoping someone with more knowledge than me could comment on the relevance of this observation, if there is any.

@Ghoul
@OldGHGuy
@Photon

I don't know who the GH experts here are, so forgive me if I left you out

I have the same exact gh, and I noticed last night it does draw a little foamy. Other gh I have does draw a little cleaner in terms of foam. Gold tops are good though, the sleep is still deep. So I’m curious as well. Hard to believe it’s a quality issue but I don’t know

Also I do notice a bit of the vacuum while drawing.. I’m guessing reading other posts that that could be the issue ? Need to let it vent I guess

 

[Ghoul]

I think he's talking about the air bubbles that form in the syringe when you draw from the recon'd vial, not when reconning the vial.

I get that too with Q's HGH if I draw really quick using a 31g. I assume it's just pressure from having to push the liquid through a small space (31g) really quick. If I use a thicker needle like a 29g, the air bubbles don't form.

I didn’t mean to suggest foaming only matters during reconstitution, it’s the same whenever it occurs, foam is foam. If one vial is more prone to forming foam than another in the same conditions, it’s going to be due to one of the factors I mentioned.

OP noted one formulation did it when drawing and the other didn’t, which points to something being different between the two.

That said, if you’re very gentle when reconstituting, you might avoid foaming even when a vial is prone to it, so that’s good practice generally. I saw a lot less foaming after switching to larger gauge needles for less pressure while reconstituting, 21-22 gauge. After switching to these Nokor vented (equalizes pressure as you fill or draw) reconstitution needles it doesn’t ever happen:

 

[lipzz17]

You can just throw a needle in and vent it.

Yes thats what i will do, this can damage the peptide or not ? Putting air before bacwater

 

[Ghoul]

Yes thats what i will do, this can damage the peptide or not ? Putting air before bacwater

Releasing pressure is fine, though technically, if you worked in a pharmacy or hospital you’d be fired after the FDA inspector caught you not using a filtered venting needle and letting that unsterile air into the vial:

 

[Photon]

After switching to these Nokor vented (equalizes pressure as you fill or draw) reconstitution needles it doesn’t ever happen:

View attachment 370089

Does the anti coring mechanism work?
It is technically 16G

 

[Garganzola]

Just to have them. Current cycle is Test/Deca. Coach might throw in Primo or EQ later tho. I’ve been stocking up on everything incase WWB goes down. Nobody else has these prices and reliability right now.

i mean primo prices are maybe 10-15% cheaper than local. Its not drastically drifferent. Maybe its more reliable since its been tested. I dont touch Deca since i am on finesteride. Are you competing or something? I am just a gym bro and do test and primo 400/300 and anavar at the end. Its kinda enough.

 

[Ghoul]

Does the anti coring mechanism work?
It is technically 16G

I use the 18g version and there’s no coring in 3ml peptide vials at all. They’re really nice if you can get a good deal for them. I think Med Lab Supply has them for 50¢ each in a case of 100.

 

[oldage]

I hate to ask but can you point me to the filters you’d use for this?

PTFE for oil
PES for peptides

 

[RocketSurge0n]

i mean primo prices are maybe 10-15% cheaper than local. Its not drastically drifferent. Maybe its more reliable since its been tested. I dont touch Deca since i am on finesteride. Are you competing or something? I am just a gym bro and do test and primo 400/300 and anavar at the end. Its kinda enough.

I am training to compete, ya.