S1L3NC3D
Member
Please provide your research. You havent provided anything to this point but your opinion without posting links to research you are claiming.
MESO-Rx
Anabolic Steroids
New Hgh - floaters?
- Thread starter thunkaboutit
- Start date
Please provide your research. You havent provided anything to this point but your opinion without posting links to research you are claiming.
riggspersonal
Member
It's not my opinion it is information i put out there for discussion to hopefully reach a conclusion
S1L3NC3D
Member
Im adding to the discussion by asking for your source of information. Please provide sources.
IndividualMan
Member
@ grok is this true typa information
Realrobinhood
New Member
Anyways, I dont really understand what filtering does to the aggregation problem, its still damaged after filtering, it reappears after a few days, so you can guess it never fixed the problem. When it reaches your body its probably a damaged structure anyways. what you think? obv filtering is good for other bad stuff, but just saying it aint removing the aggregation completly.
riggspersonal
Member
I already said that it was AI output. It provided some sources for it's reasoning that I'm reviewing and will share once complete.
I'm not suggesting one way or another is the right way. Just trying to determine what is correct. There aren't abundant sources of information on this subject for obvious reasons. Even in true pharmaceutical labratory settings they don't use perpendicular filtering because of shear risk - that is very clearly documented. They use parallel filtering. So one is left asking why that is.
I've read ghoul's posts on the subject and am clear on his stance. Now I'm just trying to find supporting information or otherwise. I don't wish to build up antibodies that attack exogenous HGH in my body.
I think this is a good discussion for all of us to have.
Elektrobot
Member
Bunch of short bus hero's in here, just regurgitating bs they've seen in telegram and reddit from other short bus hero's.
Hey AI, I'm to stupid and lazy to know how to actually learn on my own. Please spoon feed me something quickly before my mom makes me give her ipad back.
Hey AI, I'm to stupid and lazy to know how to actually learn on my own. Please spoon feed me something quickly before my mom makes me give her ipad back.
riggspersonal
Member
Nice contribution to the conversation. And lol at insinuating that there are high quality sources supporting one point of view or the other OR that AI can't be a valuable tool or resource in the quest for knowledge. If there were, it wouldn't be openly debated or misunderstood
Elektrobot
Member
There are volumes of data on this topic that have been shared here, along with direct testing evidence from Jano showing the effects on HGH under all sorts of conditions.
Don't be a lazy. Go read. Stop asking to be spoonfed.
And for fck sake stop asking chat bots for advice
Chat bots aren't trained to give the most precise, scientific, factual and reliable data...........
Publicly accessible AI's are trained to keep you happy so you will keep using it. They know patterns of human communication, and will respond to you in whatever way they think will keep you engaged. I can get chat gpt to tell me the earth is flat.
Go do some actual learning dude.
It only sounds that way to you because you are stupid and sensitive about it, so it feels like an affront.
Whoa dude! Like you’re so insightful! Nah bro your answers are all condescending trash while you aim to be superior and intellectual. If you were that you’d post up multiple citations how filtering removes the aggregate problem as well as not showing it damages the cat piss generic GH we all are taking since we’re not talking about sero. Nah you’d rather just be a moody cunt and tell us to go read rather than share on the forum meant to help others Mr. I know everything about GH. Prob small as hell with this attitude you carry. Why don’t you actually contribute with what the guys asking for instead of bash him calling him a retard.There are volumes of data on this topic that have been shared here, along with direct testing evidence from Jano showing the effects on HGH under all sorts of conditions.
Don't be a lazy. Go read. Stop asking to be spoonfed.
And for fck sake stop asking chat bots for advice
Chat bots aren't trained to give the most precise, scientific, factual and reliable data...........
Publicly accessible AI's are trained to keep you happy so you will keep using it. They know patterns of human communication, and will respond to you in whatever way they think will keep you engaged. I can get chat gpt to tell me the earth is flat.
Go do some actual learning dude.
It only sounds that way to you because you are stupid and sensitive about it, so it feels like an affront.
Elektrobot
Member
The more you talk, the shorter your bus gets....
I’ve no dog in fight but this goes for anyone, I’m hoping nobody is getting their info from Reddit. It’s a cesspool of retards
Ok bro you're so smart. Prove him wrong. Prove that filtering our Chinese bathtub GH doesn’t hurt the substance. Cmon man I’m dying to hear it. I got my helmet on and am in the shortbus waiting for you Mr. Bus Driver probably looking like Chris Farley in Billy Madison
Lmao true story
Elektrobot
Member
Filtering ANY protein based therapeutic improves its quality. This includes glp1's and every other peptide therapeutic
Pharma filters EVERYTHING
Filtering protein based therapeutics is a practice used to IMPROVE quality and patient outcome.
Thinking you are smarter than pharma is wild
Below is a chart showing the improvement in rHGH after filtering
It shows a reduction in particles in 1ml of rHGH >1um in size from 36,000 to 300 after filtering.
riggspersonal
Member
Pharma also uses expensive parallel filtration systems vs the perpendicular filtering we can do with syringes, which is why I question whether we should say "pharma does it, so we should too".Filtering ANY protein based therapeutic improves its quality. This includes glp1's and every other peptide therapeutic
Pharma filters EVERYTHING
Filtering protein based therapeutics is a practice used to IMPROVE quality and patient outcome.
Thinking you are smarter than pharma is wild
Below is a chart showing the improvement in rHGH after filtering
It shows a reduction in particles in 1ml of rHGH >1um in size from 36,000 to 300 after filtering.
View attachment 373976
Edit: I'll read the study you linked since it does seem that it's specific to syringe filters.
Last edited:
Do you know what Jano uses before every HGH and peptide test he does? Answer: a 0.22um PTFE filter. Moral of the story here is you shouldn't believe everything Ghoul says.
Not always.
Maa et al. (1996). Membrane fouling in sterile filtration of recombinant human growth hormone. Biotechnol Bioeng. 50(3):319-28
Agreed.
IF they contain the correct excipients.
Maa et al. (1998). Investigation on fouling mechanisms for recombinant human growth hormone sterile filtration. J Pharm Sci. 87(7):808-12
The irony is when Ghoul argues that UGL HGH needs to be filtered because it doesn't contain all of the excipients that pharma does, that is actually what leads to aggregation during filtering. The pharma formulations contain the correct excipients to prevent aggregation during filtering. UGL most likely does not.
PTFE or PES?
Elektrobot
Member
This doesn't specify what membrane type was used
This study used hydrophobic membranes.
We use hydrophilic membranes. No surfactants required
"When the hydrophobic interface was occupied by surfactant molecules, the equilibration kinetics ceased to generate aggregates, thereby minimizing membrane fouling. This study clarified the cause of such an unusual fouling phenomenon upon microfiltration."
