A sober look at HGH

[ostrichsak]

Yes 100% correct. Go peddle secretagouges on TikTok

TikTok? Now that's just ghey.

 

[Rand]

I’m sticking to 5-10mg of SS-31 for now. I saw that clinical trials for Barth Syndrome went as high as 40mg a day, but that’s for patients with the actual condition. The most cited studied regimen is 0.25 mg/kg, which would still put me around 17-25mg daily. I figured I’d start low, you can always ramp up, but you can't 'un-inject.' Even at 5mg, I’ve already seen my resting HR drop by 5-7 bpm, which is a huge relief while running Reta and GH.

As for Epithalon, I’m sticking to the 10-20 day 'blitz' at 5mg. I know some protocols suggest doses 10x smaller, but after another night of sleeping like I was in a coma, 5mg feels like the sweet spot. If it’s not placebo, this stuff is magic. I'm definitely finishing the course.

Same here for rhr

85 to 73

 

[KOArtist]

Stop harshing our buzz man, we got thousands of iu’s in the fridge, dayumm

 

[bananafeet]

Stop harshing our buzz man, we got thousands of iu’s in the fridge, dayumm

Hey bro I'm not bashing HGH.

It's obviously some good sh*t if people buy it. People aren't dumb.

I wonder if it can be used a bit more safely as either a microdose for skin/cartilage or big bolus with insulin on heavy training days.

I think if I didn't respond so badly to it I wouldn't have looked closely at the drug....

 

[strixsir]

I mean we are on a steroid boards, almost everything we take harms our body.

Your logic makes zero sense in so many ways. Plus you have zero real experience or understanding of HGH and you just keep reading studies and books that sure are a very important piece of info but needs to be accompanied by real world facts and use, specifically tailored to the individual and his current state.

Can HGH get you to be in a pre diabetic status? Sure. Is there like 10+ ways to avoid this? Yes there are. Is this worth it? Depends on the personal goal of a person and what he wants to achieve.

Is it good to use HGH if you have already a compromised insulin sensitivity like yourself? Nope it is not.

I have labs with perfect insulin sensitivity and an average BG of 85 and hb1ac of 5/5.2 triglycerides around 45/55 and insulin levels low as fuck using 12/14IU of HGH daily for months and an igf1 of 380/350 so not even crazy high.

Sides? Close to zero. Benefits? Plenties.

Would I suggest the same to anyone? Nope, as everything needs to be tailored to the person and his/her response to the drugs.

Hello,

please Could you expand on what benefits you Experience from HGH use?

legit asking, no leg pulling.

i workout in a relatively high end gym where a chunk of members are competitors or atleast aspirational BBers, So when they talk about GH use, i dont hear much apart from water retention and their metformin use.

 

[xrayphoton13]

Yes 100% correct. Go peddle secretagouges on TikTok

You do realize tesamore

We don’t talk about gey secretagouges here man.

Tesa can give you a greater igf-1 than high dose HGH. I've seen it on labwork here many times. Hardly "gey".

 

[Billbo98]

You do realize tesamore

Tesa can give you a greater igf-1 than high dose HGH. I've seen it on labwork here many times. Hardly "gey".

It’s got a pretty Gey ROI for how much it costs compared to to generics…if you respond well to Tesa you win respond just as well to actual GH if not better

 

[kegg408]

You do realize tesamore

Tesa can give you a greater igf-1 than high dose HGH. I've seen it on labwork here many times. Hardly "gey".

Tesamorelin stimulates your own pituitary, so it’s still limited by normal feedback and your gland’s max output. Injected HGH bypasses that system and raises IGF-1 in a dose-dependent way, which means high-dose GH can push levels far beyond what your pituitary can produce. When people say tesa gives higher IGF-1, they’re usually comparing it to low-dose GH, not high-dose. Apples to apples, exogenous GH has the higher ceiling.

 

[Billbo98]

Tesamorelin stimulates your own pituitary, so it’s still limited by normal feedback and your gland’s max output. Injected HGH bypasses that system and raises IGF-1 in a dose-dependent way, which means high-dose GH can push levels far beyond what your pituitary can produce. When people say tesa gives higher IGF-1, they’re usually comparing it to low-dose GH, not high-dose. Apples to apples, exogenous GH has the higher ceiling.

Atta guy thank you for taking the energy I didn’t have to teach this guy something

 

[bananafeet]

GH plays a pivotal role in regulating body growth and development, which is modulated by sex steroids. A close interplay between estrogen and GH leads to attainment of genderspecific body composition during puberty. The physiological basis of the interaction is not well understood. Most previous studies have focused on the effects of estrogen on GH secretion. There is also strong evidence that estrogen modulates GH action independent of secretion. Oral but not transdermal administration of estrogen impairs the metabolic action of GH in the liver, causing a fall in IGF-I production and fat oxidation. This results in a loss of lean tissue and a gain of body fat in postmenopausal women and an impairment of GH effect in hypopituitary women on GH replacement. The negative metabolic sequelae are potentially important because of the widespread use of oral estrogen and estrogen-related compounds.
Estrogen affects GH action at the level of receptor expression and signaling. More recently, estrogen has been shown to inhibit Janus kinase/signal transducer and activator of transcription signaling by GH via the induction of suppressor of cytokine signaling-2, a protein inhibitor for cytokine signaling. This represents a novel paradigm of steroid regulation of cytokine receptors and is likely to have significance for a diverse range of cytokine function. (Endocrine Reviews 25:

No idea what the last part means but the first part is about E2.

Gonadal steroid priming enhances the GH response to pharmacological stimuli in both sexes (10,11). GH and estrogen levels show positive correlations in prepubertal girls and boys (12, 13). Testosterone supplementation stimulates GH secretion and increases IGF-I levels in boys. However, the effect of testosterone is dependent on aromatization to estrogen because treatment of boys with nonaromatizable androgens (oxandrolone and dihydrotestosterone) fails to increase GH secretion (1416). This is further supported by the studies in pubertal boys and adult men given tamoxifen, an antiestrogen, which abrogates the stimulatory effect of testosterone on GH (17, 18).

Source: attached

 

[kegg408]

Atta guy thank you for taking the energy I didn’t have to teach this guy something

I see it alotnin reddit. The hype around these analogs is wild.

Saw a guy saying that hgh is better for muscle growth and a little fat loss and tesa was better for fat loss.

People arent understanding how they work at all. Its kinda funny really

 

[SmallTitsIRL]

After reading the last 6 pages of this thread, some facts, some bullshit and even personal attacks including 1 guy coming out as autistic. I don't have much to add as I didn't do much research on GH, so I could only add my personal experience, which is quite positive, do your cardio, stay lean-ish, eat healthy and most of the side effects stay away.

Now, to actually try an contribute to the conversation.

When we talk about GH we can assume 99% of the time we are talking about Somatropin which has a half live of 3 hours. But there's also Somatrogon (Ngenla) which on the other side is a long acting rHGH having a half live of 28 hours and dosage seems to be 3x higher than Somatropin. I know Somatrogon is used mainly in pediatrics, and having a longer half live is to avoid the children's discomfort with daily injections. I'm still doing my research on both, so I apologise if I'm wrong somewhere.

Has anyone here have any experience with both rHGH and could give his input if there are any differences, and what those are? If so, could you include injection schedule with both, precisely for Ngenla did you do 1 bolus dose weekly or tried dosing it 7x weekly (EOD maybe?).

Appreciate it!

 

[Billbo98]

After reading the last 6 pages of this thread, some facts, some bullshit and even personal attacks including 1 guy coming out as autistic. I don't have much to add as I didn't do much research on GH, so I could only add my personal experience, which is quite positive, do your cardio, stay lean-ish, eat healthy and most of the side effects stay away.

Now, to actually try an contribute to the conversation.

When we talk about GH we can assume 99% of the time we are talking about Somatropin which has a half live of 3 hours. But there's also Somatrogon (Ngenla) which on the other side is a long acting rHGH having a half live of 28 hours and dosage seems to be 3x higher than Somatropin. I know Somatrogon is used mainly in pediatrics, and having a longer half live is to avoid the children's discomfort with daily injections. I'm still doing my research on both, so I apologise if I'm wrong somewhere.

Has anyone here have any experience with both rHGH and could give his input if there are any differences, and what those are? If so, could you include injection schedule with both, precisely for Ngenla did you do 1 bolus dose weekly or tried dosing it 7x weekly (EOD maybe?).

Appreciate it!

Ngenla is trash don’t waste your money. The long half life is not beneficial for bodybuilding purposes

 

[SmallTitsIRL]

Ngenla is trash don’t waste your money. The long half life is not beneficial for bodybuilding purposes

-.-
My question wasn't if it was good or not. Not everything is about bodybuilding, some are curious and want to learn, which is my position in this thread.

My question was if there was someone with experience using it, how they used it, and what could they report from using both Somas.

 

[Billbo98]

-.-
My question wasn't if it was good or not. Not everything is about bodybuilding, some are curious and want to learn, which is my position in this thread.

My question was if there was someone with experience using it, how they used it, and what could they report from using both Somas.

Fair enough

 

[ostrichsak]

I see it alotnin reddit. The hype around these analogs is wild.

Saw a guy saying that hgh is better for muscle growth and a little fat loss and tesa was better for fat loss.

People arent understanding how they work at all. Its kinda funny really

Just because people (incorrectly) act like secretagogues are god's gift to humanity that cures all that afflicts them and improves the otherwise unimprovable because they beat all in every category for any reason, doesn't mean that they can't still offer benefits.

My post was never meant to insinuate that CJC-1295/IPA can replace exogenous GH nor do I see what I made any crazy claims as to such. It was directed towards someone who mentioned Tesamorelin specifically.

Like all things that are discussed on this forum, as long as folks understand the side effects and make an informed decision based on those and adjust for individuality & goals, that's their decision to make. I'm not here to talk anyone out of that either. Just offering up food for thought to add to the dataset with which people are making said decisions.

What I see though is lots of people spitting out Tesamorelin like it's magic with no downside and that's not the reality of it. It's been around a few decades now and has only gained it's popularity as of late (relatively speaking) in a rapidly moving space. I think Tesa is outdate info and prefer other options for similar benefits with decreased risk profile & downsides. Because of this, I also prefer other (and more current) options for their pathways & effects over Tesa which is why I suggested looking into them.

Someone called me gay as a result so I guess that means I'm officially accepted as one of y'all now? I'm honored that a n00b like me would be accepted so freely into this illustrious group of distinguished gentlemen.

I also wouldn't put too much weight in much that gets posted on Reddit, for the record. I don't know if people were aware but I think a few of them may not quite live up to the self-assigned title of subject matter expert that they can project.

 

[kegg408]

Just because people (incorrectly) act like secretagogues are god's gift to humanity that cures all that afflicts them and improves the otherwise unimprovable because they beat all in every category for any reason, doesn't mean that they can't still offer benefits.

My post was never meant to insinuate that CJC-1295/IPA can replace exogenous GH nor do I see what I made any crazy claims as to such. It was directed towards someone who mentioned Tesamorelin specifically.

Like all things that are discussed on this forum, as long as folks understand the side effects and make an informed decision based on those and adjust for individuality & goals, that's their decision to make. I'm not here to talk anyone out of that either. Just offering up food for thought to add to the dataset with which people are making said decisions.

What I see though is lots of people spitting out Tesamorelin like it's magic with no downside and that's not the reality of it. It's been around a few decades now and has only gained it's popularity as of late (relatively speaking) in a rapidly moving space. I think Tesa is outdate info and prefer other options for similar benefits with decreased risk profile & downsides. Because of this, I also prefer other (and more current) options for their pathways & effects over Tesa which is why I suggested looking into them.

Someone called me gay as a result so I guess that means I'm officially accepted as one of y'all now? I'm honored that a n00b like me would be accepted so freely into this illustrious group of distinguished gentlemen.

I also wouldn't put too much weight in much that gets posted on Reddit, for the record. I don't know if people were aware but I think a few of them may not quite live up to the self-assigned title of subject matter expert that they can project.

Well ill never get that time back.

 

[ostrichsak]

Well ill never get that time back.

You're welcome.