Why do some people run growth hormone releasing peptides instead of HGH?

[Proud Pangolin]

sleeping better, raising my IGF to the highest quadrant of my natural state (115 Mg/ml inicial), improving my skin and hair, and experiencing a slight anabolic/lipolytic effect.

I'm 30 years old, my physique is great with reta 3mg week, but I've lost a lot of volume due to several nights of very poor sleep.

went from 94 kg to 87 kg in one month.

Ok so this is tricky:

-generally from all what you said, i would absolutely tell you that Tesmorelin + Ipamorelin is the eight choice for you

However you also said, that your insomnia/bad sleep comes from reta? i had the same problem, which is why i dont really like Reta.

Now Tesamorelin+Ipamorelin in general really improved my sleep a lot. However when i git insomnia from Reta, it didnt help.

What helped though was HGH. HOWVER this doenst mean its the same for you.

What you could try with Reata is, moving your carbs close to your sleep and maybe taking 800mg of phosphatidylserine right before bed to lower cortisol.
Most if the insomnia from Reta appears on low carbs. In my opinion, this is, because during night your bloodsugar dropps to low and your body releases cortisol. So potatos before bed may help.


So to answer you question: For most of your goals: Tesa+Ipa however to help with insomnia from Reta, HGH may be the better choice based on MY EXPERIENCE.

 

[Macaco brazil]

Ok so this is tricky:

-generally from all what you said, i would absolutely tell you that Tesmorelin + Ipamorelin is the eight choice for you

However you also said, that your insomnia/bad sleep comes from reta? i had the same problem, which is why i dont really like Reta.

Now Tesamorelin+Ipamorelin in general really improved my sleep a lot. However when i git insomnia from Reta, it didnt help.

What helped though was HGH. HOWVER this doenst mean its the same for you.

What you could try with Reata is, moving your carbs close to your sleep and maybe taking 800mg of phosphatidylserine right before bed to lower cortisol.
Most if the insomnia from Reta appears on low carbs. In my opinion, this is, because during night your bloodsugar dropps to low and your body releases cortisol. So potatos before bed may help.


So to answer you question: For most of your goals: Tesa+Ipa however to help with insomnia from Reta, HGH may be the better choice based on MY EXPERIENCE.

Or if my body doesn't adapt, switch to tirzepatide. I'm in my fifth week on 3mg, they said the body adapts (metabolically) up to 8 weeks. Do you use tirzepatide? How much per week?

perhaps gradually reducing the retatrutide dose until a tolerable dose is found.

 

[thejumpingsheep]

i want to disagree. GHRP's wont mean automatically that they improve your sleep and timining is more cruicial than with GH. You have to take them right before falling asleep as they will result in a GH spike very fast while when injecting GH the spike will reach is max. only hours after

These are support drugs that act like catalysts. In other words, they amplify your natural cycle. If you are having issues with an HGHS then odds are you had issues without it to begin with or your levels were so low that even with inconsistency, it made no impact on your sleep.

Either case, the odds of "messing" up sleep with an HGHS is far lower than going straight HGH. This is doubly true for ones that have longer half life. HGH on the other hand will absolutely mess up your sleep cycle if taken at the wrong time. It bypasses your normal cycle entirely and skips straight to the end result.

 

[thejumpingsheep]

Desensitization
Desregulação do sistema devido à liberação contínua de GH, além de problemas de pressão ocular e intracraniana com cjc DAC.
• GHRH receptor begins to respond less

• Increasingly less effect with the same use

Negative feedback

• Hypothalamus increases somatostatin

•The body begins to block its own GH.

I wanted to use something that wouldn't cause those side effects and that I could use continuously. Have you had any experience with tesamorelin + ipamorelin, HGH?

Desensitization has not been proven by anyone and I have my doubts. There are old guys (40s-50s), like me, who have natural IGF1 levels of 250 and I have another friend, same age as me, with natty level of 350. This is our baseline... if long term exposure causes desensitization then there is no way our IGF1 would be this high at our age.

We can also look at it from the other perspective. Do people regain sensitization if their IGF1 is low? This does not seem to be the case. In fact it seems if someone is low, they stay low and might even see it decline further.

There is no solid evidence of feedback mechanism in either direction.

Last, based on what I have read around here, it seems that the ones who *might* get "desensitization" are indeed the ones blasting Somatropin. How many posts have we seen on here about guys pinning and not seeing expected results? They then raise their dosage. Certainly the argument usually circles around the purity of the HGH but maybe that wasnt the problem?

I am not a HGH and IGF1 expert but my experience with it so far, has shown no desensitization response. If anything, it seems my body is hyper responding.

Once again look at my data. I have a higher IGF1 using CJC+DAC, 1mg/wk during cruise than I did taking up to 4.6iu (or about 1.5mg) Somatropin daily during cycles. Time will tell I guess.

 

[Adamfulton]

Most likely they think that gh costs more than it does lol

 

[BendigoShafter]

Most likely they think that gh costs more than it does lol

You mean my crippling $1.60/day HGH habit?

 

[Proud Pangolin]

These are support drugs that act like catalysts. In other words, they amplify your natural cycle. If you are having issues with an HGHS then odds are you had issues without it to begin with or your levels were so low that even with inconsistency, it made no impact on your sleep.

Either case, the odds of "messing" up sleep with an HGHS is far lower than going straight HGH. This is doubly true for ones that have longer half life. HGH on the other hand will absolutely mess up your sleep cycle if taken at the wrong time. It bypasses your normal cycle entirely and skips straight to the end result.

Our sleep cycle is more compleicated than you think. However in general i agree with you, still to claim per dafault that peptides will always be superior to HGH is simpy not true. It depends on the person.

A person with healthy sleep? Well that person wont need either.
Now with GHRH/GHRP you can fuck up the timing. In general you would want the injections AFTER you fell asleep which obviously isnt possible.

Let me take me as an example (my sleep is fucked up since i was a kid).

1. 100mcg CJC no dac + GHRP-2: really improved my sleep. was really nice. Took it for 3 months, after that i stopped due to vaccation etc. after like 2 months when i started it again (even though my sleep was now a lot better than last time instarted it, this time i took it for some fatburning and because i had it lying around) NOW it worsened my sleep!!!

2. 2mg Tesamorelin+ 600mcg Ipamorelin: In general didnt really improve my sleep. Sometimes even worsened my sleep but then again so did CJC and GHRP however with Tesa it was more pronounced.

(Which had in my opinion to do with the fact, that i got real bad water rentention from Reta which caused/worsened my sleep apnea/snorring)

=> so i had a large spectrum with GHRH/GHRPs from disney princess sleep to terrible sleep

3. HGH at lower dosages really improves sleep, at higher dosages worsesn it. Also again you sleep may suffer because your muscous swell and you get sleep apnea/start snorring.

When my sleep was REALLY terrible fron Reta though, my Tesa didnt help with that. A shot of 3 IU HGH before bed and i slept like a toddler the first time for weeks.

 

[thejumpingsheep]

Our sleep cycle is more compleicated than you think. However in general i agree with you, still to claim per dafault that peptides will always be superior to HGH is simpy not true. It depends on the person.

A person with healthy sleep? Well that person wont need either.
Now with GHRH/GHRP you can fuck up the timing. In general you would want the injections AFTER you fell asleep which obviously isnt possible.

Let me take me as an example (my sleep is fucked up since i was a kid).

1. 100mcg CJC no dac + GHRP-2: really improved my sleep. was really nice. Took it for 3 months, after that i stopped due to vaccation etc. after like 2 months when i started it again (even though my sleep was now a lot better than last time instarted it, this time i took it for some fatburning and because i had it lying around) NOW it worsened my sleep!!!

2. 2mg Tesamorelin+ 600mcg Ipamorelin: In general didnt really improve my sleep. Sometimes even worsened my sleep but then again so did CJC and GHRP however with Tesa it was more pronounced.

(Which had in my opinion to do with the fact, that i got real bad water rentention from Reta which caused/worsened my sleep apnea/snorring)

=> so i had a large spectrum with GHRH/GHRPs from disney princess sleep to terrible sleep

3. HGH at lower dosages really improves sleep, at higher dosages worsesn it. Also again you sleep may suffer because your muscous swell and you get sleep apnea/start snorring.

When my sleep was REALLY terrible fron Reta though, my Tesa didnt help with that. A shot of 3 IU HGH before bed and i slept like a toddler the first time for weeks.

Im just talking generalities. Because they support your cycle, odds are, as long as your cycle is ok, they wont mess with you. HGH is direct inject. You need to know when to time it and your dosage.

I think what you are highlighting is sleep cycle isnt consistent. It can change. But that just reinforces the idea that HGH is harder to use for that purpose. If your cycle changed, how do you know when to inject HGH? It becomes a moving target.

This is why I like longer half life. DAC makes it so that CJC is very hard to screw up. At worst you screw up 1 day, but you are fine the remainder of the week.

The worry is whether or not there is any truth behind the idea of desensitization. I dont see any real evidence proving it and it remains to be seen in my case. So far, ive been on it for about 3 months and my IGF1 was through the roof. Ill take another test in a few weeks just to verify that it was really over 400 and not just a blip. I did reduce dosage by 20% to get that number down.

My sleep has done nothing but improve since I started and I can see the results in my HRV chart. I used to be in the high 30s range and this past month ive averaged about 46.

 

[Fabee777]

Ok so this is tricky:

-generally from all what you said, i would absolutely tell you that Tesmorelin + Ipamorelin is the eight choice for you

However you also said, that your insomnia/bad sleep comes from reta? i had the same problem, which is why i dont really like Reta.

Now Tesamorelin+Ipamorelin in general really improved my sleep a lot. However when i git insomnia from Reta, it didnt help.

What helped though was HGH. HOWVER this doenst mean its the same for you.

What you could try with Reata is, moving your carbs close to your sleep and maybe taking 800mg of phosphatidylserine right before bed to lower cortisol.
Most if the insomnia from Reta appears on low carbs. In my opinion, this is, because during night your bloodsugar dropps to low and your body releases cortisol. So potatos before bed may help.


So to answer you question: For most of your goals: Tesa+Ipa however to help with insomnia from Reta, HGH may be the better choice based on MY EXPERIENCE.

Interesting answer. I personally started CJC&Ipamorelin to alleviate sleep disturbance during the cutting (apart from retaining as much LBM as possible). The next step will be trying HGH to better understand which one works best.

 

[Avies48]

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