Triptorelin - interesting study that says it reverses ASIH

[CubbieBlue]

Anabolic steroids purchased on the Internet as a c... [Fertil Steril. 2010] - PubMed result

 

[Michael Scally MD]

Anabolic steroids purchased on the Internet as a c... [Fertil Steril. 2010] - PubMed result

Excellent Find! Thanks. One of the concerns for the development of an AIH treatment is to raise awareness among the medical community. For far too long and continuing, AIH is seen as a necessary evil of AAS use, AAS users are not deserving of treatment, and that at best NO treatment is necessary. What about AAS use for 3, 6, 9, or more months? What about improper TRT for years?

In this case,it appears a GnRH agonist - [ame="http://en.wikipedia.org/wiki/Triptorelin"]Triptorelin - Wikipedia, the free encyclopedia@@AMEPARAM@@/wiki/File:Triptorelin.png" class="image"><img alt="" src="http://upload.wikimedia.org/wikipedia/commons/thumb/9/9d/Triptorelin.png/220px-Triptorelin.png"@@AMEPARAM@@commons/thumb/9/9d/Triptorelin.png/220px-Triptorelin.png[/ame] was the treatment. This has been reported previously. [This is also known to cause HH when used in PrCa.]


Pirola I, Cappelli C, Delbarba A, et al. Anabolic steroids purchased on the Internet as a cause of prolonged hypogonadotropic hypogonadism. Fertility and Sterility;In Press, Corrected Proof. [Does anyone have access to the full-text?]

Objective To report a case of hypogonadotropic hypogonadism due to the chronic abuse of anabolic steroids purchased over the Internet.Design Case report.Setting Endocrinology unit of the University of Brescia.Patient(s) A 34-year-old man.Intervention(s) A single dose (100 [mu]g) of triptorelin (triptorelin test).Main Outcome Measure(s) Clinical symptoms, androgen normalization, levels of serum testosterone, follicle-stimulating hormone, and luteinizing hormone.Result(s) Within 1 month, the patient's serum testosterone was in the normal range, and he reported a return to normal energy and libido.Conclusion(s) The World Anti-Doping Code has proved to be a very powerful and effective tool in the harmonization of antidoping efforts worldwide, but it is insufficient to combat this illegal phenomenon. To tackle the serious side effects caused by doping we believe that it is necessary to increase monitoring and adopt severe sanctions, particularly with regard to Internet sites.

 

[Tyler81]

Single dose of triptorelin gets bodybuilders hormones going again

 

[CubbieBlue]

Excellent Find! Thanks. One of the concerns for the development of an AIH treatment is to raise awareness among the medical community. For far too long and continuing, AIH is seen as a necessary evil of AAS use, AAS users are not deserving of treatment, and that at best NO treatment is necessary. What about AAS use for 3, 6, 9, or more months? What about improper TRT for years?

In this case,it appears a GnRH agonist - Triptorelin - Wikipedia, the free encyclopedia was the treatment. This has been reported previously. [This is also known to cause HH when used in PrCa.]


Pirola I, Cappelli C, Delbarba A, et al. Anabolic steroids purchased on the Internet as a cause of prolonged hypogonadotropic hypogonadism. Fertility and Sterility;In Press, Corrected Proof. [Does anyone have access to the full-text?]

Objective To report a case of hypogonadotropic hypogonadism due to the chronic abuse of anabolic steroids purchased over the Internet.Design Case report.Setting Endocrinology unit of the University of Brescia.Patient(s) A 34-year-old man.Intervention(s) A single dose (100 [mu]g) of triptorelin (triptorelin test).Main Outcome Measure(s) Clinical symptoms, androgen normalization, levels of serum testosterone, follicle-stimulating hormone, and luteinizing hormone.Result(s) Within 1 month, the patient's serum testosterone was in the normal range, and he reported a return to normal energy and libido.Conclusion(s) The World Anti-Doping Code has proved to be a very powerful and effective tool in the harmonization of antidoping efforts worldwide, but it is insufficient to combat this illegal phenomenon. To tackle the serious side effects caused by doping we believe that it is necessary to increase monitoring and adopt severe sanctions, particularly with regard to Internet sites.

What can you tell us about triptorelin specifically:

How it works (difference from clomid/nolvadex)
Availability
How long it has been around
Etc.

The wikis says that it eventually decreases LH and FSH, after an initial boost. Any thoughts on how one dose for this guy basically restarted him?

Thanks,