MESO-Rx
Anabolic Steroids
Scrotal tightness
- Thread starter rjsiwelhj
- Start date
Axl
New Member
I'm not sure if I understand your question right. I assume you are on TRT???
If you are on TRT, it is most probably caused by the shut down of LH. That makes your testis shrink. Adding HCG makes your balls "hang" again.
If you are on TRT, it is most probably caused by the shut down of LH. That makes your testis shrink. Adding HCG makes your balls "hang" again.
I wonder if rjsiwelhj means something else other than testicle size. When I first read this, I assumed he was talking about the "tightness" that occurs, for example, when you're out in the cold, or when you are having sex.
It could be just me, but if I am sexually aroused, the scrotum goes from loose into a pretty tight configuration.
In fact, the better I feel hormonally, the tighter it is throughout the day. It's only loose if I'm unaroused or it's a real hot day.
It could be just me, but if I am sexually aroused, the scrotum goes from loose into a pretty tight configuration.
In fact, the better I feel hormonally, the tighter it is throughout the day. It's only loose if I'm unaroused or it's a real hot day.
marianco
Doctor of Medicine
Some patients on testosterone replacement therapy have noticed this phenomenon of scrotal tightness.
One explanation:
1. Low testosterone levels cause a loss of the Cremasteric Reflex.
2. The Cremasteric Reflex elicited by stroking the inner upper thigh downward. The normal reflex is a contraction of the cremasteric muscle that pulls up the scrotom and testis of the stroked side. (It requires intact nerves on the spine at L1 and L2. Interestingly, upper and lower motor neuron dysfunction can cause the loss of this reflex also.)
3. Low testosterone levels lead to a hypersensitivity of the neurotransmitter/hormone receptors involved with this reflex. (The involved neurotransmitters and receptors I don't know yet.)
4. Testosterone therapy then leads to an exaggerated cremasteric reflex - and thus tightened scrotum. (In boys, an exaggerated cremasteric reflex can lead to the misdiagnosis of undescended testes.)
5. Once the body gets use to its former testosterone levels, the receptor hypersensitivity and exaggerated cremasteric reflex is reduced to normal levels - leading to resolution of the problem.
As part of the physical exam, the loss of the cremasteric reflex is one clue as to the presence of a low testosterone state.
I'm glad it seems transient for the most part, as Novice experienced.
Another associated and probably related phenomenon is numbness and less sensitivity during sex - particularly oral sex - in the testicles that occurs with testosterone replacement therapy.
One explanation:
1. Low testosterone levels cause a loss of the Cremasteric Reflex.
2. The Cremasteric Reflex elicited by stroking the inner upper thigh downward. The normal reflex is a contraction of the cremasteric muscle that pulls up the scrotom and testis of the stroked side. (It requires intact nerves on the spine at L1 and L2. Interestingly, upper and lower motor neuron dysfunction can cause the loss of this reflex also.)
3. Low testosterone levels lead to a hypersensitivity of the neurotransmitter/hormone receptors involved with this reflex. (The involved neurotransmitters and receptors I don't know yet.)
4. Testosterone therapy then leads to an exaggerated cremasteric reflex - and thus tightened scrotum. (In boys, an exaggerated cremasteric reflex can lead to the misdiagnosis of undescended testes.)
5. Once the body gets use to its former testosterone levels, the receptor hypersensitivity and exaggerated cremasteric reflex is reduced to normal levels - leading to resolution of the problem.
As part of the physical exam, the loss of the cremasteric reflex is one clue as to the presence of a low testosterone state.
I'm glad it seems transient for the most part, as Novice experienced.
Another associated and probably related phenomenon is numbness and less sensitivity during sex - particularly oral sex - in the testicles that occurs with testosterone replacement therapy.
Last edited:
Axl
New Member
Great info. Very recognisable.
Do you have any reference documents for this Marianco? I would like to know more abiut that. Thanks!
Do you have any reference documents for this Marianco? I would like to know more abiut that. Thanks!
marianco
Doctor of Medicine
I don't have specific information on the loss of reflexes with low testosterone levels. It is based on clinical observations of a physician I know, who does TRT.
You can look up each individual reflex on google - e.g. for definitions.
Another reflex that may be lost with low testosterone levels is the Bulbocavernosus reflex.
The reflex is elicited by squeezing the glans penis (or clitoris in women). This results in a contraction of the external anal sphincter. During the rectal/prostate exam, this can be tested (of course, most easily with men) by squeezing the tip of the penis while examining rectal sphicter tone.
You can look up each individual reflex on google - e.g. for definitions.
Another reflex that may be lost with low testosterone levels is the Bulbocavernosus reflex.
The reflex is elicited by squeezing the glans penis (or clitoris in women). This results in a contraction of the external anal sphincter. During the rectal/prostate exam, this can be tested (of course, most easily with men) by squeezing the tip of the penis while examining rectal sphicter tone.
marianco
Doctor of Medicine
dano79 said:
Currently, I think they do return, though gradually.
