2 Fat Loss Drugs On My Radar

Oh So me being hungry because my appetite is exaggerated by something just throws thermodynamics out the window. Forgot about that one.

How does it not? You already made a good point for why it does in your post... You're saying yourself that diet is compromised IE energy intake is compromised. That essentially nullifies 50% of the 2nd law of thermodynamics... And it has the potential to turn the other 50% (cardio IE energy expenditure) into a zero sum game.

It's not like thermodynamics no longer exist here, but they're made a lot less efficient... It would make more sense to try to correct the inefficiency than try to offset the inefficiency with more energy output. If you were driving and blew a tire that slowed you down, would you push the gas pedal down further or change the tire?
 
I am more than aware of the laws of thermodynamics. It is in my field.

Care to apply any of them in this case?

If you manage to, I will do the rest and see if we can reach a reasonable conclusion.

And if you are right, I will admit it without a second thought.

I never expected that I would be challenged in physics here. It is my strongest subject.

I am serious and you are totally welcome to explain what you mean. I will be so happy to be wrong. Honestly,not being ironic. This has triggered my scientific interest.
Calories in vs calories out.

burn more energy than required = loss of energy (taken from stores in body).

consume more energy than is burned = energy stored(fat gain)

You’re either using your energy for activity and releasing it in some form, or you’re storing.

he’s fat and wants to lose weight, so diet and cardio and use will power. I’ve been on ssris before myself and had this issue. same thing with mk. Just because you feel hungry doesn’t mean you are. Gherlin (Hunger hormone) triggers this response. If youre gaining fat you’re obviously not hungry or starving yourself. It’s a hormone issue. You need to “fight” your body to lose weight or I should say go against your natural instincts

Oh by the way, WAY easier said than done. I’m just saying I think people way over complicate things and look other ways out WITHOUT covering the basics. Master the basics then add the extra stuff to it. I’m fully guilty of this myself.
 
How does it not? You already made a good point for why it does in your post... You're saying yourself that diet is compromised IE energy intake is compromised. That essentially nullifies 50% of the 2nd law of thermodynamics... And it has the potential to turn the other 50% (cardio IE energy expenditure) into a zero sum game.

It's not like thermodynamics no longer exist here, but they're made a lot less efficient... It would make more sense to try to correct the inefficiency than try to offset the inefficiency with more energy output. If you were driving and blew a tire that slowed you down, would you push the gas pedal down further or change the tire?
You absolutely murdered it.
I will post a different reply to answer to his post since I am incapable of quoting 2 responses for some reason.
 
How does it not? You already made a good point for why it does in your post... You're saying yourself that diet is compromised IE energy intake is compromised. That essentially nullifies 50% of the 2nd law of thermodynamics... And it has the potential to turn the other 50% (cardio IE energy expenditure) into a zero sum game.

It's not like thermodynamics no longer exist here, but they're made a lot less efficient... It would make more sense to try to correct the inefficiency than try to offset the inefficiency with more energy output. If you were driving and blew a tire that slowed you down, would you push the gas pedal down further or change the tire?
Perhaps I misinterpreted his post.

that is the main issue here. He is consuming more than he is burning. So to offset this he either increases activity, decreases energy intake, or both.

When I said that it was a tad bit of sarcasm, because the fix to losing the weight is exactly that, become more efficient with your calories and energy expenditure. Now that you explained what he meant it makes a lot more sense, fix the issue with the SSRI instead of trying to balance the energy issue caused by the increase in appetite.
 
Oh So me being hungry because my appetite is exaggerated by something just throws thermodynamics out the window. Forgot about that one.
You could just say well just don't eat so much but life is complicated. I find that after I don't eat for a while I start to feel really bad and after I have a meal I get more well being so I wouldn't just be denying myself food I would be denying myself well being.
 
Calories in vs calories out
burn more energy than required = loss of energy (taken from stores in body)
consume more energy than is burned = energy stored(fat gain)

You’re either using your energy for activity and releasing it in some form, or you’re storing.

he’s fat and wants to lose weight, so diet and cardio and use will power. I’ve been on ssris before myself and had this issue. same thing with mk. Just because you feel hungry doesn’t mean you are. Gherlin (Hunger hormone) triggers this response. If youre gaining fat you’re obviously not hungry or starving yourself. It’s a hormone issue. You need to “fight” your body to lose weight or I should say go against your natural instincts

Oh by the way, WAY easier said than done. I’m just saying I think people way over complicate things and look other ways out WITHOUT covering the basics. Master the basics then add the extra stuff to it. I’m fully guilty of this myself.
Calories in,is compromised. Due to extensive hunger caused by the medications. Common side effect,you can look it up. No,you won't control it if it gets you.
Calories out is also compromised by:
1) I've heard some stuff metabolism related. I am not sure. Regarding this type of drugs.
2) It is highly likely that his ability to maintain a stable training routine is compromised as well due to mental stuff,which are actual.

Calories in and calories out is a measurable concept.
Energy...well...this is not just a simple "energy" matter. You are oversimplifying energy.
This is a multidisciplinary issue. And in order to examine it as efficiently as one can, you need to take other stuff into consideration such as the pathophysiology of the brain and the effects of these drugs to the pathophysiology of the brain,which I won't get into,as it can get really weird with the terminology and concepts.

The laws of thermodynamics are not exactly applicable here. At least not on their own.
It is a multidisciplinary issue. It goes beyond physics,way beyond.

Fight your body and natural instincts.
Natural instincts.
We are not talking natural here.
We are talking altered pathophysiology of the brain via external factors and subsequently the effects on appetite. Nothing natural about it. Natural goes to the bin.

Therefore,the primary factor causing the energy intake imbalance,should be first ruled out and afterwards...it MAY be exactly as you said.
I say may,because there are other side effects as well that could possibly alter the calories out factor as well. But not all of the SSRI patients have these. It's a hit and miss.

That's my leftovers. I am rusty. Had physics and biophysics 7 years ago. Now I am months away from getting my degree.

However, you are right. Calories in calories out.
But if there are no external factors.

And lastly,if someone is hungry to death,that means he is hungry to death,even if he had eaten 10k calories before 10 minutes.
I repeat,we are not talking "natural" here.

The ordinary rules don't easily apply here,and in this case,the laws of thermodynamics.

We are not talking ideal models. We are actually talking about far from ideal models.
This is not strictly physics here.

Reason I quit mirtazapine. I lasted one week more or less. It was uncontrollable.
Calories out was also compromised.
Bro I couldn't fucking walk for the love of me,the next day. Training? No way.
Not even want to mention about calories in.
Brutally craving sweet.
I hate sweet. I am a salt guy.
 
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You could just say well just don't eat so much but life is complicated. I find that after I don't eat for a while I start to feel really bad and after I have a meal I get more well being so I wouldn't just be denying myself food I would be denying myself well being.
I agree with you. But the reality of it is that is body building. Which I have a skewed perception compared to the average person of what I am willing to do and understand the sacrifices it takes to go above and beyond.

you must deny yourself some well being in the short term for some well being in the long term sometimes, it isn’t a forever thing. It sounds like you may go to hard on restricting calories if you begin to feel that bad, I have been in this pattern before. You have to find YOUR happy medium to reach your goals.

regardless talk to the professionals and see if they can find a way to make things ease up a bit for you.
 
Perhaps I misinterpreted his post.

that is the main issue here. He is consuming more than he is burning. So to offset this he either increases activity, decreases energy intake, or both.

When I said that it was a tad bit of sarcasm, because the fix to losing the weight is exactly that, become more efficient with your calories and energy expenditure. Now that you explained what he meant it makes a lot more sense, fix the issue with the SSRI instead of trying to balance the energy issue caused by the increase in appetite.
The main issue is the main issue.
It is the one you outlined. And it is simple

The management of it is what's complex and requires knowledge you and me both don't have.
 
How does it not? You already made a good point for why it does in your post... You're saying yourself that diet is compromised IE energy intake is compromised. That essentially nullifies 50% of the 2nd law of thermodynamics... And it has the potential to turn the other 50% (cardio IE energy expenditure) into a zero sum game.

It's not like thermodynamics no longer exist here, but they're made a lot less efficient... It would make more sense to try to correct the inefficiency than try to offset the inefficiency with more energy output. If you were driving and blew a tire that slowed you down, would you push the gas pedal down further or change the tire?
Regarding the tire.
It will blow the fuck out of the rim eventually.
Mechanical fatigue. Elastic deformation has its limits.

In our case, fatigue.
You can outdo the compromised intake. You can't but let's say you do.
You may blow the rubber part out of the rim if you keep pressing the pedal.
 
I agree with you. But the reality of it is that is body building. Which I have a skewed perception compared to the average person of what I am willing to do and understand the sacrifices it takes to go above and beyond.

you must deny yourself some well being in the short term for some well being in the long term sometimes, it isn’t a forever thing. It sounds like you may go to hard on restricting calories if you begin to feel that bad, I have been in this pattern before. You have to find YOUR happy medium to reach your goals.

regardless talk to the professionals and see if they can find a way to make things ease up a bit for you.
That's what I am trying to convey is that on medication your appetite isn't normal and even a 500 calorie defecit feels more like 1000+ so it isn't just a little bit of well being you give up. In comparison this is my 3rd week off medication and I'm eating in like 500+ calorie defecit without trying while it took all my willpower to do the same on medication
 
That's what I am trying to convey is that on medication your appetite isn't normal and even a 500 calorie defecit feels more like 1000+ so it isn't just a little bit of well being you give up. In comparison this is my 3rd week off medication and I'm eating in like 500+ calorie defecit without trying while it took all my willpower to do the same on medication
Continue your talks with your psychiatrist.
You guys will figure it out. Stay positive even if it's hard to.

Thank you to
@Eman
And
@Pineapples4Puss

For the great conversation. Cheers.
 
Will power when you have uncontrollable cravings is extremely tough, and people who haven’t experienced it are very quick to say “quit bitching and deal.”

I’m a 32y/o female. I’ve been on a tricyclic since age 10 for extreme IBS and migraines, an SSRI for the pst 4 years for anxiety, and T4 since age 20 after having most of my thyroid removed. I can put down 3,000 calories in one hour-long sitting without blinking an eye. I’ve had to learn that going to bed hungry every night for months just to maintain or slowly lose weight is just my life. It sucks, and it’s really hard, but the alternative of not being on these treatments is even worse so I’ve found a way for my goals to drive my decisions, but it took me a very long time to get to that point.

Sorry for the rambling, but that’s been my experience. I feel like if I, as a woman, am able to deal with it and still succeed while consuming 1500 cals a day for over a year (yeah, should have done more diet breaks lol) then you can too, just plan better and really embrace the hunger.
 
I could deal with the cravings from 2 other ssris that I have been on,but the most uncontrollable was fucking mirtazapine.
Unreal.

I am not on anything anymore, I am one of the lucky ones.
But my mental shit could come back any time.
GAD here. An extreme case of GAD,combined with panic attacks.
Nowadays it's just mild GAD.
All caused by the brainfuck getting my degree caused.

Ah,and you didn't ramble. No worries. I know how the mental shit is.
Stay tight!
 
That's what I am trying to convey is that on medication your appetite isn't normal and even a 500 calorie defecit feels more like 1000+ so it isn't just a little bit of well being you give up. In comparison this is my 3rd week off medication and I'm eating in like 500+ calorie defecit without trying while it took all my willpower to do the same on medication
Can you tell us what medication it was and what dose? I am not seeing that, maybe I'm just missing it. That would be helpful.

So, in summary here is the situation:
- You were taking a medication (unknown which and what dose yet, please share)
- You went off of said medication.
Questions: Did you quit it cold turkey or wean off? Are you doing this on your own or under doctor supervision?
- You are now in the middle of a cut at 500 cal deficit per day, but it is extremely hard. WAY harder than it feels like it should be.
Questions:
1. How deep into this cut are you? How many weeks have you been at a deficit?
2. Are you doing a bunch of cardio/physical activity on top of your deficit?
3. If so, are you making up for these calories at all?
4. Are you following any kind of refeed schedule, such as on weekends?
5. Were you in a deficit before you quit your meds? Or did you start the cut after stopping the meds?
6. Are you taking any other drugs at all? Marijuana? Dabs? Wax? THC edibles? CBD? Nicotine such as cigs or vaping or gum? Benzodiazepines? Alcohol? Heroin? Crack? Meth? Speed? PCP? Poppers? Drinking reindeer piss? (lolz)


Please just copy and paste those questions and answer them as best you can. They all are very relevant to the situation here.
 
I've been trying to find a way to source it because it's very expensive
Here in Mexico Trulicity and Victoza are about 150-200 USD for a months supply at the max dose.

Saxenda is specifically approved for weight loss. Perhaps get a doc to script it and get insurance to cover it?
 
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