24k Pharma US Domestic Source

Not sure I understand. You are using 24ks pharma adex? The adex I received from 24k is US pharma.

I've had anastrozole from AstraZeneca, Teva, and the brand that 24k carries. I actually had some of the AstraZeneca leftover until about a month ago. I haven't noticed any differences in potency.

If it isn't working for you I'd strongly suggest getting blood work to see what is going on.

EDIT: Forgot to add... after I get my E2 rise back up (it was crashed per my blood work a few weeks ago)I was ok at 0.25mg EOD. I stupidly bumped up to 0.5 EOD because I felt I was holding too much water. After about 3 doses at 0.5 I started to hate life. Clicking joints, loss of erection stength, and fatigue.

I crash my E2 very easily. I'm going back to 0.25 EOD.


The adex is generic. And manufactured in india.
 
The adex is generic. And manufactured in india.
True, but it is a USA product which is manufactured under much stricter standards, and guidelines than say Indian meds, made for Indian market. It is also made by Natco which is a very reputable company.

Look where much of our meds are manufactured. Little is made here these days. Watson cyp from Portugal, Teva from Israel, my Exemestane script is Alvogen and comes from Ireland, etc.

After all this hooplah I ordered some Adex, and Nolva. Everything exactly how it should be. All imprints match, and adex is working as well as my old script adex did for years before switching to Exemestane. Went from running my script Exem, to that, seamlessly. Will post blood work soon hopefully as I am due for a TRT Dr visit.

Can't speak for his UGL stuff as I only ordered meds. Shipping was decent, not super fast, but not awful. Emails always prompt.
 
The adex is generic. And manufactured in india.

I think we are misunderstanding each other here. Yes, it is produced under contract by an Indian manufacturer. But it isn't the typical "Indian generic" that people talk about that have Q/A issues. Any pharmaceutical product distributed in the USA has to have FDA approval for THAT specific product for THAT specific manufacturer. It isn't an Indian domestic product. It is a product that is specifically for the US pharma market. It is US pharma grade.

http://www.medscape.com/viewarticle/724417

In excess of 50% of all US pharma medications are manufactured overseas. They are held to the same standards are pharmaceutical companies producing domestically.

If I misunderstood what you were saying let me know... but when you say "Indian generic" I think most people are thinking of the products sold on sites like ADC/Reliable, etc which are Indian domestic products and not subject to FDA inspection and QA. They are only regulated by the Indian ministry that is responsible for pharmaceuticals.

That doesn't mean that your point isn't valid -- there have been lots of issues with generics and bioequivalence or absorption issues. There have also been specific issues with Indian manufacturers of US bound pharma products -- the FDA has asked for more money to increase their inspections. However, I'd be shocked if the vast majority of anastrozole wasn't made overseas.

Not discounting your experience at all. If I were you, I'd get my blood work so I'd know for sure. No one wants to play around with high E2 or the related issues. If I was closer to my blood work date I'd get it myself and share. If there is a problem with this product then everyone should know. Fortunately I haven't had any issues with it...
 
Im not disagreeing with you. As far as generics go. However, i have known guys on trt, and have heard of woman with cancer, not being able to afford their pharmacy script and use the exact same manufacturer of adex that were using, and others, and have different results, including myself. The same manufacturer of the adex from that your currently using is being sold by the indian pharmacies such as adc etc..if it goes through the same regulations, i couldnt tell you.

Edit: i was taking 800mg test for 2 weeks with no ai. Starting thursday i took 1mg. 2 days i took 2mg. Its only been 5 days. However, on a script, 2mg would knock me out. id much rather be low and work up then high and work down and get to where im comfortable. Usual dosing of .25 eod at 120 to 200mg test weekly will keep e2 around 20 to 30. I am not, nor have i, said this adex is not good. Questionable right now at best.
 
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Hey everyone. First off, just wanted to say thank you to those who have contributed with their knowledge and/or feedback. I'm also very appreciative that everyone has been careful not to explicitly discuss the brands of medication publicly, thank you.

That being said, if anyone is not satisfied with products, please contact me and I'll be happy to discuss it with you. I cannot guarantee pharmaceutical grade, or even close, for our UGL products, but I have confidence in our pharmacy medications and will stand behind them fully. Thanks again for everyone's involvement.
 
Edit: i was taking 800mg test for 2 weeks with no ai. Starting thursday i took 1mg. 2 days i took 2mg. Its only been 5 days. However, on a script, 2mg would knock me out. id much rather be low and work up then high and work down and get to where im comfortable. Usual dosing of .25 eod at 120 to 200mg test weekly will keep e2 around 20 to 30. I am not, nor have i, said this adex is not good. Questionable right now at best.
You realize if you went to the pharmacy, with a script, odds are it would be the same/similar arimidex? Most insurance isn't paying for brand name meds.

I would be interested to see your bloodwork on 1mg/day.
 
You realize if you went to the pharmacy, with a script, odds are it would be the same/similar arimidex? Most insurance isn't paying for brand name meds.

I would be interested to see your bloodwork on 1mg/day.
Why do you say it would be interesting to see the blood work on 1mg a day? Im not insulting you Im just curious.
 
You realize if you went to the pharmacy, with a script, odds are it would be the same/similar arimidex? Most insurance isn't paying for brand name meds.

I would be interested to see your bloodwork on 1mg/day.
The pharmacy does offer generics, they do, and are cheaper. This goes with many meds.
bloodwork is not an option right now. there wouldnt be any doubts.
 
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Why do you say it would be interesting to see the blood work on 1mg a day? Im not insulting you Im just curious.
Why not? If he is running 1mg a day and his estrogen isn't in the shitter on a TRT dose of test the answer is clear.

The pharmacy does offer generics, they do, and are cheaper. This goes with many meds.
I am not sure what your point is here? You are saying exactly what I just said. If you took your script to the local CVS odds are you would get this exact Arimidex, or a similar Generic. Look at the price of Astra Zeneca Arimidex. Just about NO insurance will pay for that when generics are readily available.
Code:
http://www.goodrx.com/anastrozole#/?filter-location=&coords=&label=Arimidex&form=tablet&strength=1mg&quantity=30.0&qty-custom=
 
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Im not disagreeing with you. As far as generics go. However, i have known guys on trt, and have heard of woman with cancer, not being able to afford their pharmacy script and use the exact same manufacturer of adex that were using, and others, and have different results, including myself. The same manufacturer of the adex from that your currently using is being sold by the indian pharmacies such as adc etc..if it goes through the same regulations, i couldnt tell you.

Edit: i was taking 800mg test for 2 weeks with no ai. Starting thursday i took 1mg. 2 days i took 2mg. Its only been 5 days. However, on a script, 2mg would knock me out. id much rather be low and work up then high and work down and get to where im comfortable. Usual dosing of .25 eod at 120 to 200mg test weekly will keep e2 around 20 to 30. I am not, nor have i, said this adex is not good. Questionable right now at best.

I've seen exemestane manufactured by Natco available from Indian pharmacies, but I've never seen Natco anastrozole.

I had some Natco exemestane that I was taking and I thought it was bunk from a lack of sides. I bought some RC anastrozole and starting using it instead. I guess about 5-6 days before my blood work, I started taking the exemestane again. My test level was over 4k...i had injected quite a bit in the 3 days before my blood test. My e2 was crashed.

Perhaps you just don't feel it? I dunno. Like I said, the adex from 24k I have has given me the normal benefits, and when I increased dosage I started getting low e2 sides.

Hopefully one of us can get blood work soon and put this to bed.
 
I dont know man. Generics arent always up to par. Stopped my adex over 2 weeks ago..started his thursday. Dropped my test down to cruise. Oily skin, fatigue, water retention. Took 2 mgs last 2 days..dont do that. 1 mg thurs through sat. I feel nada. Any good adex or pharmacy adex id be wishing i didnt do that right now.
I could be wrong..dont listen to me. I think generics have some leeway as far as dosing and indian generics have been known to be bunk. Glad its working for you.
Bullshit. Fda approved means it's within a fucking small margin of ~1mg / tab.

You think generic blood pressure medicine you get at cvs is just willy nilly? Are you imagining some mad scientist saying "eh, a little bit of this, a little bit of that..."

Generic pharma grade is fine. My Mylan is technically "generic" and it's good to go. Way better than any UGL's adex, any day.

When you say you don't know, it is clear.
 
Natco is questionable and has been scrutinized by the fda in the past. They are one of the cheapest generics, in any knockoff, they produce. Generics do not have the same quality control measures as name brand meds, as much as you would like to believe. Including dosage. Many have been pulled, recalled and stopped distribution because it was found out later by the fda. Including natco.
I never said the adex youre taking was not adex. Indian pharmacies are questionable at best. As far as the natco arimidex, i couldnt tell you.

im a pretty calm guy most of the time..if you have something you disagree with me on, i respect that. No reason to be a smart ass.
 
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Most of the time, generics are made in the same faculties.


I am unfamiliar with that brand, and it is good to see the Fda doing their job.

In regards to being a smart ass, it tends to come out when I see what I deem to be nonsense spewed for unknowing readers to believe. All pharma companies I am sure have had bad batches, or issues. Either way, I am fairly confident thus far these products are good. Normally I run Mylan, which is trustworthy, and so far I can't tell a difference from the switch. Maybe there would be a minuscule measurable difference if you ran bloods, maybe not? Either way, certainly not bunk and j would say it's closely dosed to 1 mg as that's what I was running before. Certainly I would know if it was complete trash by now.
 
Most of the time, generics are made in the same faculties.


I am unfamiliar with that brand, and it is good to see the Fda doing their job.

In regards to being a smart ass, it tends to come out when I see what I deem to be nonsense spewed for unknowing readers to believe. All pharma companies I am sure have had bad batches, or issues. Either way, I am fairly confident thus far these products are good. Normally I run Mylan, which is trustworthy, and so far I can't tell a difference from the switch. Maybe there would be a minuscule measurable difference if you ran bloods, maybe not? Either way, certainly not bunk and j would say it's closely dosed to 1 mg as that's what I was running before. Certainly I would know if it was complete trash by now.
Natco is the adex you are currently on.
 
In further review, I now see why you referenced Natco.

Either way, time will tell. I appreciate your views here, and it is always good to question, that we agree on. Let's just see how this stuff plays out for members. Luckily, I have some other adex in case issues do flair up (not that I foresee it).
 
To be honest, i didnt see this whole conversation going this far by me posting my experience over 5 days and questioning your usage. if and when it happens, ill be the first to admit im wrong. The adex was only questionable, never bunk. I could be wrong about a lot of things..im not doubting that or admitting to it. This only makes me want to get bloodwork done sooner. Unfortunately, my only options are wait for the doc or drive 4 hrs to get it done. I will say my mood has elevated the past 2 days. If my e2 was high or low i get lethargic, depressed, and i overthink and dwell on things pretty hard. I also do not know how high my levels had gotten before starting either.
 
I really wouldn't call Natco the cheapest or a producer of knockoffs.

The maker of Tylenol has had their US production shutdown before due to FDA issues.

Brand names are not above the fray when it comes to GMP issues, QA, or cost-cutting.

Natco has also partnered with Teva and Hospira. And, those partnerships are what I think is relevant. All. The pharma companies now produce meds overseas... Including their name brand items. But, with generics it is a pretty high percentage.

I think over 85% of the US market is generic. Only a small portion is brand name.

Natco has had FDA issues directly related to manufacturing and QA. As have the vast majority of pharma companies -- both at home and abroad.

Your adex may be crap and I'm very glad you posted your experience in the thread. I hope you can get blood work and let us know. Hopefully you can get some other AI if your symptoms don't abate. That said, it wouldn't matter if your adex was one of another 8-9 US generics made overseas. They still have to get FDA approval and are subject to inspections and regulation. It has nothing to do with it being in India or being made by Natco. The company distributing should have QA on their side as do the other generic manufacturers. Of course there can be issues... Especially with bioequivalence, but ultimately it is fairly rare. If you were getting some kind of overseas med from a lesser developed country that wasn't FDA approved then I think that part of your argument would have more validity.

The final point I'd make is that if their are widespread issues (say your bottle isn't the problem but an entire batch is) it will be reported to the FDA pretty quickly. Women, of course, are the main users of anastrozole, and their doctors closely monitor their estrogen levels.

I wish you luck. Hope your issues resolve themselves. Really hate you are having issues. E2 is nothing to play around with.
 
To be honest, i didnt see this whole conversation going this far by me posting my experience over 5 days and questioning your usage. if and when it happens, ill be the first to admit im wrong. The adex was only questionable, never bunk. I could be wrong about a lot of things..im not doubting that or admitting to it. This only makes me want to get bloodwork done sooner. Unfortunately, my only options are wait for the doc or drive 4 hrs to get it done. I will say my mood has elevated the past 2 days. If my e2 was high or low i get lethargic, depressed, and i overthink and dwell on things pretty hard. I also do not know how high my levels had gotten before starting either.
Either way, your experiences are worth something to us as a community.

I am still unsure about generics having lower standards than brand name drugs, though. Doesn't make sense to me, but I suppose anything is possible.
 
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