MESO-Rx
Anabolic Steroids
27 and about to start TRT. Freaked out with lots of questions!
- Thread starter Coptic
- Start date
My MRI came back a few weeks ago...there is a 5mm mass on the left portion of the anterioir pituitary (technically considered a microadenoma). My neurosurgeon decided against surgery as the only symptoms I have are related to the low testosterone. He's watching and waiting (MRI again in 6 months)
any input regarding my labs/symptoms with my TRT?
any input regarding my labs/symptoms with my TRT?
So I just received my 4-point salivary cortisol and DHEA-S profile from ZRT labs:
Morning (8am)=8.2 ng/ml (3.7-9.5)
Noon=1.1 (1.2-3.0)
Evening=0.8 (0.6-1.9)
Bedtime=0.6 (0.4-1.0)
DHEA-S=8.8 ng/ml (7-23)
It seems at first glance that my noontime and possibly evening cortisol are definitely on the low side. I have an appointment with my endo on Monday, but if ANYONE has any thoughts to shed on the matter, it would be much appreciated. I should state that I am not currently taking any meds for my hashimotos's (which was confirmed again about a week ago with a high anti-TPO tiiter) as my doc wanted to address the possible adrenal issues before tackling the thyroid problem. I am not DHEA or any other supplements save for a multivitamin and my TRT/HCG protocol.
thanks again
Morning (8am)=8.2 ng/ml (3.7-9.5)
Noon=1.1 (1.2-3.0)
Evening=0.8 (0.6-1.9)
Bedtime=0.6 (0.4-1.0)
DHEA-S=8.8 ng/ml (7-23)
It seems at first glance that my noontime and possibly evening cortisol are definitely on the low side. I have an appointment with my endo on Monday, but if ANYONE has any thoughts to shed on the matter, it would be much appreciated. I should state that I am not currently taking any meds for my hashimotos's (which was confirmed again about a week ago with a high anti-TPO tiiter) as my doc wanted to address the possible adrenal issues before tackling the thyroid problem. I am not DHEA or any other supplements save for a multivitamin and my TRT/HCG protocol.
thanks again
benchingover500
New Member
Sometimes people have the remanants of their thymus removed and their hashimotos goes away. Just a thought.
Everything effects everything else. If you get the thyroid straightened out the low PM cortisol may also resolve. The testosterone might - probably not.
You undrstnd this well.
Recent update:
My TPO came back really elevated (dont have the exact vlue currently, but was approximately 20-30 IU/mL ). Started on armour 1grain (60mg) daily, hydrocortisone 10mg around noon and 7.5 mg at ~4pm.
I have noticed that I am less fatigued during midday, but still fell wiped out during the evening time. Going for another total/fee test +e2, tsh, free t3, this afternoon for a floow-up apt after thanksgiving.
anyone have any insight into things I should ask about?
happy holidays
My TPO came back really elevated (dont have the exact vlue currently, but was approximately 20-30 IU/mL ). Started on armour 1grain (60mg) daily, hydrocortisone 10mg around noon and 7.5 mg at ~4pm.
I have noticed that I am less fatigued during midday, but still fell wiped out during the evening time. Going for another total/fee test +e2, tsh, free t3, this afternoon for a floow-up apt after thanksgiving.
anyone have any insight into things I should ask about?
happy holidays
Where is the evidence for this "backfilling"? The best I can locate is on a forum - backfilling hormones. This is far far from any sort of evidence and no more than BS.
Does anyone supplement their TRT with DHEA & Pregnenolone? On what basis are you doing this? More quack, quack, quack ...
If you search for "backfilling" on PubMed, you obtain the following result: BACKFILLING - PubMed - NCBI
There is not one cite dealing with hormone replacement. Regarding "backfilling AND testosterone," the result is for ZERO cites: No items found - PubMed - NCBI
There is not one cite dealing with hormone replacement. Regarding "backfilling AND testosterone," the result is for ZERO cites: No items found - PubMed - NCBI
Here are some questions that I think would be of interest.
Is there any evidence for PREG deficiency on TRT?
Is there any evidence for DHEA (or DHEA-S) deficiency on TRT?
Since TRT will also "stop" testes E2 synthesis, does this imply E2 should be administered (forward-filling)?
Since any use of DHEA & PREG will NOT occur in a vacuum, what compounds result from DHEA and/or PREG administration?
Do any of these result in compounds (intermediates), etc. that might cause concern? What about estrogens? Is DHEA converted to estrogens? [Hint: Yes]
Is PREG converted to Progesterone (PROG)? PREG is used in menopausal HRT. What effect might PROG have in the male?
And, for that matter, wouldn't this "backfilling" idea imply PROG to be also administered? If not, why?
Is there any evidence for PREG deficiency on TRT?
Is there any evidence for DHEA (or DHEA-S) deficiency on TRT?
Since TRT will also "stop" testes E2 synthesis, does this imply E2 should be administered (forward-filling)?
Since any use of DHEA & PREG will NOT occur in a vacuum, what compounds result from DHEA and/or PREG administration?
Do any of these result in compounds (intermediates), etc. that might cause concern? What about estrogens? Is DHEA converted to estrogens? [Hint: Yes]
Is PREG converted to Progesterone (PROG)? PREG is used in menopausal HRT. What effect might PROG have in the male?
And, for that matter, wouldn't this "backfilling" idea imply PROG to be also administered? If not, why?
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