750mg of DNP safety

[Barbellforeskin]

Did a bulk. Got fat (20% bf). Used DNP for three weeks. 250mg ramping to 500mg and at the end did 750 for 2 days. Down to 13% bf. It was magic. Nothing has shred fat off me that quickly. Nothing short of an incredible compound. To finish off this cut I’m doing another 2 week DNP cycle. 500mg for 2 weeks and I am wondering about pushing the dose to 750mg would be safe/worth it? I’m 175lbs depleted if that matters. 5’8. Cruising on 200mg test. Sides from 500 is severe lethargy, hot when I eat carbs, and any movement is very taxing. DNP form is powder.

 

[Liter O' Test]

so 500mg is magic but you want to do more? strong sides at 500mg imagine how much worse it will be at 750mg.
think about it.

also, I'm sure you know this, but for anyone reading this who doesn't, just because you did 750mg for 2 days doesn't mean you know how 750mg will effect you because of the half life build up.

I highly advise against this, like any compound you get diminishing returns and more sides, i think you just need to chill a bit and stop looking in the mirror.

 

[mrsloppyboo]

so 500mg is magic but you want to do more? strong sides at 500mg imagine how much worse it will be at 750mg.
think about it.

also, I'm sure you know this, but for anyone reading this who doesn't, just because you did 750mg for 2 days doesn't mean you know how 750mg will effect you because of the half life build up.

I highly advise against this, like any compound you get diminishing returns and more sides, i think you just need to chill a bit and stop looking in the mirror.

Yeah the 750 for two days reflects nothing on how it would feel for two weeks. Mg/kg safety shows 800mg being my max dose. If I feel to hit I’ll drop to 500. 500 is tolerable without carbs. This run I’m using a GLP1 so cravings shouldn’t be an issue. I suspect 750 is going to be rough but without carbs much more manageable

 

[rexy]

Read page 3 of this study. It's highly underrated as I've never seen it referenced before but it has what is IMO some of the most important details on DNP in it.

The graphs are hard to see properly because it looks like it was photographed manually, but you'll get the gist of it. it shows that people can have wildy different peak/trough responses to the same DNP dose even on a day-to-day basis. The chart on the left shows 4 people (because 2 of the curves are the same person), and how quickly they peaked/troughed from 3mg/kg.

for e.g, in the person who was tested twice under the same conditions (curves 2 and 5), curve 5 showed their peak metabolism on that day was reached after 2 hours, whereas in curve 2 on a seperate day without accumulated dosing, it was still increasing at the end of 6 hours instead of peaking at 2 hours. Both were on the same person, with the same amount of DNP (3mg/kg). Same pre-conditions before each dose as well - 15hr fasting.

Added to the unpredictability day to day, is the fact that the threshold for intolerability can be very close to the tolerable one - i.e 200mg has me barely feeling it, but 400mg will have me experiencing intense nightsweats and fatigue to the point I can't function.

If you can handle 750mg it's highly likely it was underdosed so becareful. It might mislead you when taking another vendor's DNP, thinking it's equal dosed, but it could = hospital time at 750mg.

@Trenbolonetax you may be interested in this.

 

[Jaxino]

Did a bulk. Got fat (20% bf). Used DNP for three weeks. 250mg ramping to 500mg and at the end did 750 for 2 days. Down to 13% bf. It was magic. Nothing has shred fat off me that quickly. Nothing short of an incredible compound. To finish off this cut I’m doing another 2 week DNP cycle. 500mg for 2 weeks and I am wondering about pushing the dose to 750mg would be safe/worth it? I’m 175lbs depleted if that matters. 5’8. Cruising on 200mg test. Sides from 500 is severe lethargy, hot when I eat carbs, and any movement is very taxing. DNP form is powder.

Tbh I would never use more than 250mg daily.
It's more than enough to get lean and quite fast. In any case I don't use DNP since 5 years, sides are not really worth.

 

[mrsloppyboo]

Read page 3 of this study. It's highly underrated as I've never seen it referenced before but it has what is IMO some of the most important details on DNP in it.

The graphs are hard to see properly because it looks like it was photographed manually, but you'll get the gist of it. it shows that people can have wildy different peak/trough responses to the same DNP dose even on a day-to-day basis. The chart on the left shows 4 people (because 2 of the curves are the same person), and how quickly they peaked/troughed from 3mg/kg.

for e.g, in the person who was tested twice under the same conditions (curves 2 and 5), curve 5 showed their peak metabolism on that day was reached after 2 hours, whereas in curve 2 on a seperate day without accumulated dosing, it was still increasing at the end of 6 hours instead of peaking at 2 hours. Both were on the same person, with the same amount of DNP (3mg/kg). Same pre-conditions before each dose as well - 15hr fasting.

Added to the unpredictability day to day, is the fact that the threshold for intolerability can be very close to the tolerable one - i.e 200mg has me barely feeling it, but 400mg will have me experiencing intense nightsweats and fatigue to the point I can't function.

If you can handle 750mg it's highly likely it was underdosed so becareful. It might mislead you when taking another vendor's DNP, thinking it's equal dosed, but it could = hospital time at 750mg.

@Trenbolonetax you may be interested in this.

It’s definetly properly dosed. I capsule them myself lol. I find that spreading my consumption of the DNP throughout the day (morning midday before bed) greatly reduces lethargy for me. I would assume it’s due to the peaks but the compound was already at full saturation when I split the doses on 500mg so who knows. Either way it helped. Thank you for that article that was an interesting read. I’ve never seen that article before

 

[eery]

No. Dnp over 3-5mg/kg is reckless and dumb.

Don't die.

 

[Uncle Bub]

I'm about a week in just doing 200mg a day before bed. It's working but the lethargy does suck. I wake up sweaty every day. Gonna try to last one more week on it.

 

[Ryu82]

Always ramp up with DNP. Sounds stupid but each run your body responds slightly differently. So don't just jump on 500mg out of the gate (you might not be planning to and if I missed that I apologize)

Also, no dice on the 750mg man. If it ain't broke...

 

[mrsloppyboo]

Always ramp up with DNP. Sounds stupid but each run your body responds slightly differently. So don't just jump on 500mg out of the gate (you might not be planning to and if I missed that I apologize)

Also, no dice on the 750mg man. If it ain't broke...

Idk if I’d really call it a second cycle more than a continuation of my previous 3 weeks cycle. I took 3 days off just for a break expecting it to be 2 weeks but was feeling good. I started again at 500mg and felt like regular 500mg now I’m at 750 the past 2 days. I’ll drop down immediately to 500 again if I’m feeling too much heat, need to play it safe but going up to 750 isn’t unheard of. Mg max dose for mg body weight is around 800mg according to a study I read about dose and dose accumulation

 

[Doodle]

If it works at 500mg, why increase?

I’m a small cautionary tale. I did 750mg a few years back now. The only pro was losing 1-2 pounds a day. The cons changed my whole life.

I developed cataracts. They were so severe that I went completely blind. Within weeks. Thankfully I was a surgery coordinator for an eye surgeon so I was able to get the cataracts removed.

I also developed peripheral neuropathy. My feet burned at first and then they went numb but also painful. Damaged so many nerves. After a few years feeling has slightly returned.

Seriously be careful. Don’t be dumb. I was doing so great on it during the first cycle. I lost a killer amount of weight. Not worth it when there are GLPs available now. I lost more on tirzepatide than I did with DNP. I feel amazing on tirze and there are other benefits to GLPs.

 

[nullandvoid]

I've got cataracts developing myself, way earlier than I should. Seemed to happen after my DNP run, as well. The lens of the eye is very sensitive to what DNP does. I wanted to believe it only affected females, but if you dig a bit, you'll find reasons the data is skewed like that. DNP doesn't seem to discriminate. I also had itching neuropathy on my feet afterwards that was so bad I preferred the pain of digging holes in my skin over the itching. That subsided after a week or so, though. I didn't discover the surprise gift of cataracts until I recently went to get my eyes examined because my vision had just gotten much worse in such a short period of time. Your prescription generally stops changing as you get older, so I knew something was up. Surprise motherfucker, you got cataracts.

The change wasn't immediate, so I didn't correlate it to DNP at the time. But the timing is suspicious. I am 52.

 

[Doodle]

I've got cataracts developing myself, way earlier than I should. Seemed to happen after my DNP run, as well. The lens of the eye is very sensitive to what DNP does. I wanted to believe it only affected females, but if you dig a bit, you'll find reasons the data is skewed like that. DNP doesn't seem to discriminate. I also had itching neuropathy on my feet afterwards that was so bad I preferred the pain of digging holes in my skin over the itching. That subsided after a week or so, though. I didn't discover the surprise gift of cataracts until I recently went to get my eyes examined because my vision had just gotten much worse in such a short period of time. Your prescription generally stops changing as you get older, so I knew something was up. Surprise motherfucker, you got cataracts.

The change wasn't immediate, so I didn't correlate it to DNP at the time. But the timing is suspicious. I am 52.

ah another one eh? Isn’t it horrible? So frustrating having to go through it all. The good news about cataracts is that they don’t return. You may develop scar tissue but a quick and painless laser will take care of that in 5 minutes in office. The upside to the cataract surgery is that I now have a lens inside that is prescription. Meaning I no longer need glasses.

 

[nullandvoid]

ah another one eh? Isn’t it horrible? So frustrating having to go through it all. The good news about cataracts is that they don’t return. You may develop scar tissue but a quick and painless laser will take care of that in 5 minutes in office. The upside to the cataract surgery is that I now have a lens inside that is prescription. Meaning I no longer need glasses.

Fortunately, mine aren't bad enough (yet) to force surgery, but my left eye in particular took a big hit to my prescription. I don't have health insurance so will just have to take out a small loan for when it has to happen, but like you said, the silver lining is no longer needing glasses. I figure I'll probably still need some for reading, though. I've got so many damn floaters, too, that is also on the horizon.

 

[Ghoul]

Fortunately, mine aren't bad enough (yet) to force surgery, but my left eye in particular took a big hit to my prescription. I don't have health insurance so will just have to take out a small loan for when it has to happen, but like you said, the silver lining is no longer needing glasses. I figure I'll probably still need some for reading, though. I've got so many damn floaters, too, that is also on the horizon.

Get the premium lenses that sharpen vision, improve night vision and enhance color perception.

Why just restore normal sight when it can be improved over natural?

I don't think most people are made aware it's even an option.




Insurance will usually only cover standard lenses, but you can pay the difference for the upgrade.

 

[Doodle]

Get the premium lenses that sharpen vision, improve night vision and enhance color perception.

Why just restore normal sight when it can be improved over natural?

I don't think most people are made aware it's even an option.


View attachment 324175View attachment 324176

Insurance will usually only cover standard lenses, but you can pay the difference for the upgrade.

Exactly! I used to calculate all this and get people to upgrade. It’s worth the 10k or so. A basic lens covered by insurance fixes either near or far vision. But not both. The upgraded lens does everything. I loved seeing the patients come back in after surgery. 20/20 vision and can read small print pretty much the day of surgery. I remember coming out of my surgery and saying wow I can see! It was interesting going through what I put my patients through.

 

[BigMate]

Yeah the 750 for two days reflects nothing on how it would feel for two weeks. Mg/kg safety shows 800mg being my max dose. If I feel to hit I’ll drop to 500. 500 is tolerable without carbs. This run I’m using a GLP1 so cravings shouldn’t be an issue. I suspect 750 is going to be rough but without carbs much more manageable

Thing to remember with DNP is it was banned / ‘voluntary withdrawn’ because - cataracts and other risks aside - its LD50 is considered too close to its effective dose (ie narrow therapeutic index). Depending on your weight, 750mg is maybe 1/3-1/2 of the established lethal dose.

It also has a very long half life of 5-14 days so dose accumulation is a very real problem. This all leaves very little room for error in terms of dosing. Combined with zero quality control on the product, this magnifies lethality risk substantially.

I have run up to 750mg years ago but above 500mg it’s pretty fucked, and imo carries diminishing returns for much more pain. I’d stick to minimal effective dose you have experience with ie 500 or better yet just run GLP alone

 

[MickieGord]

Fuck it. Do it lets see what happens.

 

[mrsloppyboo]

Thing to remember with DNP is it was banned / ‘voluntary withdrawn’ because - cataracts and other risks aside - its LD50 is considered too close to its effective dose (ie narrow therapeutic index). Depending on your weight, 750mg is maybe 1/3-1/2 of the established lethal dose.

It also has a very long half life of 5-14 days so dose accumulation is a very real problem. This all leaves very little room for error in terms of dosing. Combined with zero quality control on the product, this magnifies lethality risk substantially.

I have run up to 750mg years ago but above 500mg it’s pretty fucked, and imo carries diminishing returns for much more pain. I’d stick to minimal effective dose you have experience with ie 500 or better yet just run GLP alone

I’m sweating but so far so good. Day 3 on 750 is finished. Still hasn’t saturated yet I know. Cutting almost all carbs out helps with heat significantly. Last run I did 250 for 6 days 400 for 6 days then 500 for the remainder of the 3 weeks. Lost 15-19lbs of fat and had 3-5 full cheat days in that cycle where I easily ate over 5k cals. Most of the days I ate 1500-2000cal (TDEE is 2500 without DNP). The math with the TDEE increase from DNP doesn’t even come close to me losing that much fat but it happened and the mirror definitely reflects it. On paper makes 0 sense. Nothing short of incredible. Very excited to see the effects of 750mg

 

[Sampei]

I can understand 200/300mg, but even 400mg it's already close to retardiness, anything above that is full retard mode.