750mg of DNP safety

Barbellforeskin

New Member
Did a bulk. Got fat (20% bf). Used DNP for three weeks. 250mg ramping to 500mg and at the end did 750 for 2 days. Down to 13% bf. It was magic. Nothing has shred fat off me that quickly. Nothing short of an incredible compound. To finish off this cut I’m doing another 2 week DNP cycle. 500mg for 2 weeks and I am wondering about pushing the dose to 750mg would be safe/worth it? I’m 175lbs depleted if that matters. 5’8. Cruising on 200mg test. Sides from 500 is severe lethargy, hot when I eat carbs, and any movement is very taxing. DNP form is powder.
 
I dunno how anyone runs high doses of this shit for weeks. I've gone up to 400 like once or twice since I've been on and I think I'm going to pass on that from now on. Got my workout in this morning and then was useless as fuck the rest of the day. I've been so damn tired since I got home almost 12 hours ago.

It'll be 200mg or nothing for me from now on.
 
Did a bulk. Got fat (20% bf). Used DNP for three weeks. 250mg ramping to 500mg and at the end did 750 for 2 days. Down to 13% bf. It was magic. Nothing has shred fat off me that quickly. Nothing short of an incredible compound. To finish off this cut I’m doing another 2 week DNP cycle. 500mg for 2 weeks and I am wondering about pushing the dose to 750mg would be safe/worth it? I’m 175lbs depleted if that matters. 5’8. Cruising on 200mg test. Sides from 500 is severe lethargy, hot when I eat carbs, and any movement is very taxing. DNP form is powder.
175 lbs and you’re resorting to DNP to get lean? Come on, mate… you’re still hovering in the skinny-fat territory. Focus on building more muscle instead.
 
While I will never use DNP again. Especially with the advent of GLP-1 drugs. I did do as much as 600mg once and I felt like complete garbage. 400mg wasn't all that bad but 600mg was much more extreme. The increase in dosage can really hit you hard.

I personally think DNP is a very outdated and nowadays unnecessary drug.
 
I’m sweating but so far so good. Day 3 on 750 is finished. Still hasn’t saturated yet I know. Cutting almost all carbs out helps with heat significantly. Last run I did 250 for 6 days 400 for 6 days then 500 for the remainder of the 3 weeks. Lost 15-19lbs of fat and had 3-5 full cheat days in that cycle where I easily ate over 5k cals. Most of the days I ate 1500-2000cal (TDEE is 2500 without DNP). The math with the TDEE increase from DNP doesn’t even come close to me losing that much fat but it happened and the mirror definitely reflects it. On paper makes 0 sense. Nothing short of incredible. Very excited to see the effects of 750mg

did you follow a 0 or low carb diet when you lost the 20lbs? used to be rumours that dnp needs carbs to work. curious if you want to be a guinea pig and try same cals but with carbs next time see what results are

how were you getting 2000 cals with no carbs or sugar ?
 
did you follow a 0 or low carb diet when you lost the 20lbs? used to be rumours that dnp needs carbs to work. curious if you want to be a guinea pig and try same cals but with carbs next time see what results are

how were you getting 2000 cals with no carbs or sugar ?
Low carbs not no carbs. You need carbs for DNP to work
 
here's some AI slop re diet on DNP. makes sense maybe

thought there was more to it but main thing DNP just burns through glycogen reserves making your body burn fat instead of the food you just ate. probably good to have some carbs to keep body temp a bit warmer than normal there's got to be some benefit to that


k but disregarding the safety issues. eating more carbs while on dnp would increase metabolic rate so would this not mean more fat loss






Even disregarding the severe safety issues, the idea that eating more carbohydrates while on DNP would directly translate to more fat loss is a flawed understanding of how DNP works. Here's a breakdown of why:

  • DNP's Core Mechanism: DNP's primary action is to uncouple oxidative phosphorylation. This means the process that normally efficiently converts energy from food (carbs, fats, proteins) into ATP is disrupted. Instead of ATP production, the energy is released as heat. This causes a dramatic increase in metabolic rate because the body tries to compensate for the lack of ATP by burning through fuel at a much faster pace.




  • Increased Metabolic Rate = Increased Fuel Consumption (Not Necessarily Fat): While DNP does increase the rate at which your body burns calories, it doesn't selectively target fat. Your body will burn through whatever fuel is readily available, including carbohydrates, fats, and even muscle tissue (protein).
  • Carbohydrates as the Primary Fuel: When you consume a high amount of carbohydrates, they become the readily available primary fuel source for your body. With DNP in the picture, your body will burn through these carbohydrates at an accelerated rate due to the uncoupled mitochondria trying to produce energy.
  • No Guarantee of Increased Fat Loss: While the overall calorie expenditure will be higher with more carbohydrates available and DNP present, this doesn't guarantee a greater proportion of fat being burned. Your body might simply be burning through the excess carbohydrates more quickly.
  • Potential for Increased Side Effects: Providing a large and readily available fuel source like carbohydrates could potentially exacerbate the negative side effects of DNP. The increased metabolic rate leads to increased heat production. More fuel available could mean even more heat generated, further increasing the risk of hyperthermia and other dangerous complications.
  • Glycogen Replenishment: Consuming a high amount of carbohydrates will also ensure that your glycogen stores (stored glucose in muscles and liver) are full. While DNP increases energy expenditure, the body might preferentially burn through these readily available carbohydrate stores before significantly tapping into fat reserves.

Think of it this way: DNP acts like a leaky engine. It burns fuel very quickly but doesn't produce much usable energy. Supplying it with more fuel (carbohydrates) just means you're pouring more fuel into a very inefficient and dangerous engine. It doesn't magically make the engine selectively burn fat.

In conclusion, even if we completely ignore the extreme safety risks, intentionally eating more carbohydrates on DNP is not a logical strategy to increase fat loss. It's more likely to simply increase the rate at which carbohydrates are burned and potentially worsen the already life-threatening side effects of the drug. Fat loss is best achieved through a controlled calorie deficit where the body is forced to tap into its fat stores for energy, not by using a dangerous substance that indiscriminately accelerates metabolism.
 
So much information on DNP now and you still see misinformation and dangerous protocols.

Guys start reading and search the old threads from Conciliator et al or don’t use DNP at all.
 
here's some AI slop re diet on DNP. makes sense maybe

thought there was more to it but main thing DNP just burns through glycogen reserves making your body burn fat instead of the food you just ate. probably good to have some carbs to keep body temp a bit warmer than normal there's got to be some benefit to that
The drug actually requires carbs to properly function is what I mean. That’s why keto doesn’t work with DNP. It’s shredding through fat not just glycogen. I’ve been on 750mg for 2 weeks now. Honestly I’m as used to the sides as I can get. The heat sucks but is controlled with carbs but I’m getting insomnia which is really frustrating but manageable with some prescription sleeping pills my buddy gave me. More carbs = more heat. More carbs ≠ more fat burn. It’s the same as every other diet. Cals in cals out. I will say low carbs is much more bearable. Pigged out and went to dennys with buddies a couple night ago and had a shit ton of carbs. Needless to say I was dripping sweat sitting in a room temp diner lol. Cravings are rough at 750 but I’ve noticed even when I do eat like shit I still look as good as I did if not leaner than the day before. I’ll only know how much I really lost when I get off the DNP and water retention goes away
 
Keto + DNP doesn't work because the citric acid cycle breaks without any glucose available. When fatty acids are broken down they need to be fed into an energy cycle for a complete break down so that more can be broken down later. The beginning of this cycle is called the citric acid cycle. Fats enter the citric acid cycle as a 2-carbon molecule called acetate and to start off this cycle it needs to bind to another 2-carbon molecule called oxaloacetate. Without enough oxaloacetate this cycle cannot proceed. With little oxaloacetate this cycle is slowed down, thus fat burning is slowed down. Where does oxaloacetate come from? Several sources, but the main one is from pyruvate, the end product of the first step of glucose (carbohydrate) metabolism. Without enough glucose in the blood, fat burning becomes very inefficient. [...] The least effective form of dieting while on a DNP cycle is a fat diet, or ketogenic diet, but the high amounts of fat helps to slow gastric emptying, so you feel more satisfied for a longer period of time.
 
Thread '2,4-DiNitroPhenol [DNP]'
2,4-DiNitroPhenol [DNP]

It’s been discussed somewhere in the thread, there have also been tons of experiments done by folks throughout the years going high carbs, low carbs or med carbs and successfully got lean.

End of the day, the mechanism of how dnp works has nothing to do with carb intake. However, the level of heat and comfort can be related to your carb intake.
 
Thread '2,4-DiNitroPhenol [DNP]'
2,4-DiNitroPhenol [DNP]

It’s been discussed somewhere in the thread, there have also been tons of experiments done by folks throughout the years going high carbs, low carbs or med carbs and successfully got lean.

End of the day, the mechanism of how dnp works has nothing to do with carb intake. However, the level of heat and comfort can be related to your carb intake.

can you give the tl:dr of how much carbs and what kind?

a little refined sugar, honey, orange juice throughout the day to keep the process going? or breads and pasta in 3-4x meals
 
can you give the tl:dr of how much carbs and what kind?

a little refined sugar, honey, orange juice throughout the day to keep the process going? or breads and pasta in 3-4x meals
Doesn’t matter in the slightest but I’d recommend complex carbs due to slower digestion bc you should be limiting carbs. I’ve been on 750 for 2 weeks now eating like a cunt but I still look leaner
 
can you give the tl:dr of how much carbs and what kind?

a little refined sugar, honey, orange juice throughout the day to keep the process going? or breads and pasta in 3-4x meals
I don’t think there is a guideline on how much carbs you need, you have to try what you can tolerate.

DNP is pretty popular to pair with PSMF for lots of guys over at ProMuscle. So you can get away with zero carbs too.

End of the day its based on how you feel, if I remember correctly decades ago I did a complete depletion then carb cycled through out. lost 10 lbs in 2 weeks, lost another 5 of water at the end. I didn’t like the lethargy though.
 
what does DNP bring to the table that today’s GLP1 / GIP or metabolism / appetite hacking peptides don’t?

i come in peace. i’m truly curious from those who have had success with it.
I would say it’s the drastic changes you can achieve in a shorter time frame if you can keep up with the side effects. It is not something that you can run long term or even something you can even if you want to.
 
i considered it way back, when it was easy to find on the clear net websites as fertilizer. but i could never get past the side effects folks were reporting. had no idea that cataracts were a thing though. Tren’s side effects were too much to deal with after a while, i didn’t want to deal with what seemed worse.

do what you want though. i’m not in the business of telling folks what they can put in their body. 90% of the people i interact with IRL with would gasp if they saw cocktail i run. i’d tell each one to get bent if they tried to infringe on my choices.
 
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