Am I missing something??
First, Not once have you given you full stats (height, weight, history, current rountines, diagnosis, prognosis, etc) in a concise format...
Now 38 I am 5ft 11 and 188lbs (34in waist) (<36 inch at widest around gut) I have no history and was fighting fit when I suddenly fell ill. I was an athletic build without any gut at this point. Also without any health issues prior. I was 36 then.
I was laid off from work as a contractor (mass lay offs) just before this time I started getting dizzy, aches,tired. joint pain etc. Waited around 6 months. Went to the Docs, did bloods TSH was 6.4 norm range in the UK <6 most other places <3 They thought I was subclinical Hypothyroid and would not medicate until TSH >10.
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I was put onto TRT for 7 months with no follow up and just 1x Sustanon 250 shot once every 3 weeks. Rollercoaster ride of panic, anxiety etc.
Second, did you not recently mention "empty sella syndrome"?? Obviously, that would be a considerable implication. Did the doc simply state that or did they do some kind of scan or something?
I insisted that something was still wrong and they referred me to an Endo to tell me I was subclinical Hypo! They did further tests & found my Prolactin was High and my T was low. They suspected a pituitary tumour. I had an MRI and they discovered an empty Sella syndrome. They understand that I will need to supplement whatever hormones are low
You labs indicate that your Prolactin is under control with the Bromo, but I am not sure how they could determine thyroid with only T4 & TSH. Seems like they would want the T3 and further indept diagnostic with an initial read of 6.something!?!? (and I am not astute with thyroid at this time). But these thoughs occur. Seems like there is also a "reverse T4" test if merited. But again with the pituitary diagnosis how was that done. Have they scanned your thyroid by any physical means?? I dont see where the thyroid meds are doing diddly....
They initially did take TSH, T4 and T3 but they tend not to bother too much with T3 here i.e it's in range, you are still alive..it's ok. But they have only accepted the fact that I have some kind of thyroid problems as my TSH has ranged from 2 to 6 my Endo is only prescribing me Levo as it seems to have brought my TSH closer to the ideal. I will be seeing my Endo next week and I will ask to up my Levo. They only offer synthetic T4 here in the UK which is why they probably overlook the more active T3. I have had the hashi test and no thats negative .
You have not given weight and height? Please tell(at least I missed if you did).
I did give it just above!
You will find I like to take the rather obvious approach to assisting others via the use of common sense and most likely probabilty in observation. YOUR E2 is up in FATS MANS LAND - Like me. YOU... are a FATTY - like me... When you are fat IT CORROLATES that your TT levels will be low. Why not check estrone too? and confirm estrogen from outter space.??!!?!?
I agree that YES I have put weight on I am now under 14 Stones and Was 15.5 stone at my heaviest before TRT. When I had gotten ill I was at 12.5 stone without a gut. I regulary exercised then too. Putting weight on has been a RESULT of all this shit not a cause. I also found it extremely difficult doing exercise since getting ill I just could not shift the weight no matter.
It also occurs to me that "the empty sella syndrome" could in fact be a RESULT, and not an INHERENT CONDITION. Meaning perhaps it is the way it looks when one's body is not working right due to health issues that are easily changeable with exercise and diet change. Just a thought for the positive.
They have actually looked at my pituitary gland via MRI scan and it is crushed/damaged against the sella turka (bone) . The difficulty I face now is that since being on TRT I have felt awful due to a poor administration of TRT, scant regard for E2 reading etc. No AI's or Hcg. The problem I have now is doing the exercise when my recovery and endurance is so poor, dizzy , racing heart etc. Not at all what I was like when I was fit and well. I think if I can get my thyroid meds right these should really improve.
Thoughts:
- Your TSH and E2 changes in this test can only be the result of a new diet and exercise regime fruiting. I have my own suspicions that E2 as a function of adipose tissue, is not determined by the body's fat composition, BUT ITS CURRENT STATUS as to whether it is storing fat or not. But I have seen TSH go up with TRT over time, and how your thyroid meds apply I dont know or speculate.
No my TSH is down to just taking regular Levo (it's a fairly low dose of 50 right now) my E2 actually doubled as soon as I was on TRT. Now I have stopped it has halved thankfully. My TSH was all over the place after getting ill but before being diagnosed. It's been erratic and not logical. Also my diet has not changed. Not fantastic, but not bad either.
- I am wondering if the Caber drove up the FSH??
Possibly, I have only been on the caber for less than 2 months, I only got prescribed it after saying I wanted to stop TRT and see if my body will start up properly again with low TRT. But my nuts were aching a fair bit for the last couple of weeks. The same kind of ache I had when I started TRT as my balls shutdown. Is it good that my FSH is up high?
- I really dont see you LH comming up till you have a new tissue demand for testosterone. You already have the fat to create all the E2 related TT you need. It is also unclear how LH relates to TT levels ON THE DIFFERENT POINT ON THE MEASUREMENT SCALE... IME, 2-4 is where most middle aged sedentary fat guys sit.
I think you may be right here, But I am hoping to see a gradual increase as my Testes recover. Not quite sure what to expect though it's only been 10 days?
- Do you have any Gyno type development at all. Has the doc considered this and examined for it. This could explain the high prolactin if the tissue is in place to drive the demand...?
I have a little Gyno or manboobs. But fairly tight for a late 30s guy, By no means bitch tits though. It's not bad enough that I'm scared to take my top off. My GP or Endo would definitely say there was no Gyno.;-) My Prolactin also increased by 33% ish upon starting TRT.
I would like to know your height and weight and what your exercise regimen has been since you started TRT with relation to your diet please??
Also, do you recall if you were eating like a hog at the time of the tests with the high E2 and were you in a good diet/weight loss condition at this last test with the low e2. These answers would be beneficial to me personally. And I dont mean to be offensive, I just dont mince words and use the most obvious to describe so there is no miscommunication. TIA..