A GH and fat loss protocol (rhGH lipolysis) that is science-based

[Ghoul]

RE eating after dosing, I'm thinking about switching to a morning bolus injection due to sleep issues. I'm usually up around 7, do 30-45 minutes of fasted cardio and eat around 8-9. My breakfast is the same thing every day, 2 5oz lean beef burger patties and 4-5 eggs cooked in butter. Zero carbs in the morning.

Eating shouldn't have any negative effects on the GH spike due to the glycemic index of my food being zero correct?

Protein still stimulates insulin release, just 1/4 as strongly as carbs.

So it'll blunt it slightly, but not nearly as much as carbs would.

I wouldn't worry about it. It's not like it's 100% GH effects or 100% IGF effects. You'll still be tilted toward fat burning for the first few hours after the injection even with that meal.

 

[Deadpool99]

After trying to dial in my GH protocol, I’m thinking of switching from subQ to IM injections.

I’ve always done subQ and waited 2 hours before eating to maximize GH’s fat-burning (lipolysis) effect. But from what I’ve seen, the difference between IM and subQ isn’t massive—IM just peaks faster.

Because of that faster peak, IM theoretically allows better timing for fat loss if you’re eating 2 hours later. With subQ, the true optimal fasting window is more like 3–4 hours, but IM should peak and clear sooner, meaning carbs are less likely to blunt the GH pulse.

On top of that, IM clears faster, so in theory it might reduce water retention and insulin resistance effects compared to subQ due to a shorter exposure window.

That’s my current thought process, and it feels like the most optimal approach right now. Curious to hear everyone’s thoughts—am I missing anything?

Edit: In the long term, both routes yield the same IGF-1 and muscle-building outcomes to my knowledge so IM is mainly a timing and comfort optimization, so I believe none are superior but this might fit my protocol and maybe others better.

 

[Type-IIx]

After trying to dial in my GH protocol, I’m thinking of switching from subQ to IM injections.

I’ve always done subQ and waited 2 hours before eating to maximize GH’s fat-burning (lipolysis) effect. But from what I’ve seen, the difference between IM and subQ isn’t massive—IM just peaks faster.

Because of that faster peak, IM theoretically allows better timing for fat loss if you’re eating 2 hours later. With subQ, the true optimal fasting window is more like 3–4 hours, but IM should peak and clear sooner, meaning carbs are less likely to blunt the GH pulse.

On top of that, IM clears faster, so in theory it might reduce water retention and insulin resistance effects compared to subQ due to a shorter exposure window.

That’s my current thought process, and it feels like the most optimal approach right now. Curious to hear everyone’s thoughts—am I missing anything?

Edit: In the long term, both routes yield the same IGF-1 and muscle-building outcomes to my knowledge so IM is mainly a timing and comfort optimization, so I believe none are superior but this might fit my protocol and maybe others better.

Pharmacodynamic effects are what matter not pharmacokinetic. We know the pharmacodynamic effects on HSL [shown here].

What we have for intramuscular effects on fat metabolism is…. surmise.

 

[Type-IIx]

 

[RoxasShadow]

Say I am on reta and want to move hgh from morning (fasted workout) to evening.I have dinner (say a sweet potato and two salmon fillets) at 7-7:30pm, inject HGH at 9:45 and lay down. Because Reta would slow gastric emptying keeping insulin high, would the fatloss condition be negated as the time required to be kinda fasted would be much longer?

I am thinking about sleep because I train fasted; I wake up and leave home, so a subq injection would peak when i already finished and probably having my post-workout.

 

[KOArtist]

@Type-IIx i read your article, and quick question: when you say semaglutide, are you just using that as an “abbreviation”, or “catch all”, or are you declaring Sema as the heavyweight champ of GLP’s that go with rhGh? Thanks bro

 

[Type-IIx]

@Type-IIx i read your article, and quick question: when you say semaglutide, are you just using that as an “abbreviation”, or “catch all”, or are you declaring Sema as the heavyweight champ of GLP’s that go with rhGh? Thanks bro

I really like semaglutide for body comp. Per-mg it's certainly the most potent of the GLP-1, dual-G, and triple-G drugs for effecting fat loss. The newcomers to the scene bring additional blood glucose control – which is good if you're blasting GH!

 

[KOArtist]

I really like semaglutide for body comp. Per-mg it's certainly the most potent of the GLP-1, dual-G, and triple-G drugs for effecting fat loss. The newcomers to the scene bring additional blood glucose control – which is good if you're blasting GH!

Mix all 3 up and pin it, all the best of each, right?

 

[Diego90]

What would be the drawback of taking the morning hgh bolus on waking up and straight go to a hiit workout? Would it be better to wait 2h before the hiit to maximize recovery? I use to do a fasted hiit workout first thing under the rising sun, and a longer workout at the gym more hypertrophy oriented in the evening, and I try to separate them 6-7h apart.

 

[Ghoul]

What would be the drawback of taking the morning hgh bolus on waking up and straight go to a hiit workout? Would it be better to wait 2h before the hiit to maximize recovery? I use to do a fasted hiit workout first thing under the rising sun, and a longer workout at the gym more hypertrophy oriented in the evening, and I try to separate them 6-7h apart.

No drawback. There is a delay between injection and when FFA’s peak. From what I’ve read, FFA’s start measurably rising 30-60 mins post injection and peak 2-3 hours later.

But these timing differences on a practical level for maximizing fat burning are small, The main thing seems to be getting cardio in before the effect drops off around 4 hours later (or insulin rises after eating). FFAs continue to be used during the 1-2 hour recovery period so delaying breakfast if possible may use up a little more fat too.

 

[Diego90]

RE eating after dosing, I'm thinking about switching to a morning bolus injection due to sleep issues. I'm usually up around 7, do 30-45 minutes of fasted cardio and eat around 8-9. My breakfast is the same thing every day, 2 5oz lean beef burger patties and 4-5 eggs cooked in butter. Zero carbs in the morning.

Eating shouldn't have any negative effects on the GH spike due to the glycemic index of my food being zero correct?

For anabolic purpose, should I eat (carb+protein) after the hitt season, about 2-3h post hgh bolus injection (when it peaks)?

 

[Ghoul]

For anabolic purpose, should I eat (carb+protein) after the hitt season, about 2-3h post hgh bolus injection (when it peaks)?

Insulin enhances anabolic signaling (and IGF levels), so yes it would help. Whether it’s a significant or small difference I don’t know.

But habits that provide even “small increases” in the lipolytic effect for fat loss and the anabolic effect for muscle mass can add up over long periods of time.

 

[BatmanVAR]

I've been running 4IUs every night, about 2-3 hours after my last meal. I'm thinking of switching mornings and this thread has fascinated me n

Maybe I'm overthinking this, but my question is - how much would the fat loss effects be blunted if I drank a 10 calorie Monster Zero sugar (yes I know these are basically poison, but that's another discussion) about an 1-1.5 hours after pinning? I usually wake up around 8:00 or 8:30, and hit the gym around 11:00. I need caffeine about an hour or so before (I hate coffee and tea hence the monsters) so I usually drink one about 9:00 or 9:30, sometimes as late as 10:00.

Thanks

 

[Ghoul]

I've been running 4IUs every night, about 2-3 hours after my last meal. I'm thinking of switching mornings and this thread has fascinated me n

Maybe I'm overthinking this, but my question is - how much would the fat loss effects be blunted if I drank a 10 calorie Monster Zero sugar (yes I know these are basically poison, but that's another discussion) about an 1-1.5 hours after pinning? I usually wake up around 8:00 or 8:30, and hit the gym around 11:00. I need caffeine about an hour or so before (I hate coffee and tea hence the monsters) so I usually drink one about 9:00 or 9:30, sometimes as late as 10:00.

Thanks

None.

 

[BatmanVAR]

None.

Excellent, thank you for the prompt reply. I'm going to switch to this tomorrow. Wondering if I should skip my dose tonight or just do both tonight and the morning.

 

[Ghoul]

Excellent, thank you for the prompt reply. I'm going to switch to this tomorrow. Wondering if I should skip my dose tonight or just do both tonight and the morning.

If you get sides now. Hold off, there’s no real loss from the delayed injection and you could significantly worsen them.

On second thought, probably just better to wait the ~12 hours either way.. Even if you don’t get sides, you might after doubling up.

 

[BatmanVAR]

If you get sides now. Hold off, there’s no real loss from the delayed injection and you could significantly worsen them.

On second thought, probably just better to wait the ~12 hours either way.. Even if you don’t get sides, you might after doubling up.

Makes sense, I'll play it safe and wait until morning. I don't have any sides other than what I think might be minor carpal tunnel in my right hand (minor discomfort in the fleshy part below the thumb and kind of in the thumb joint itself), but I can't say 100% it's from this, because I'm old and have been weight lifting for 30 years, so I have aches and pains everywhere (herniated disk, strained shoulder, crunchy elbow, permanently tight and sore forearm, etc.) that all predated HGH usage. I just can't remember if the thumb issue was before or after.

Part of the reason I started HGH (in addition to fat loss and muscle gain as well as anti-aging) was to see if it would help with some of these issues. My shoulder is much better so I have hope.

 

[Ghoul]

Makes sense, I'll play it safe and wait until morning. I don't have any sides other than what I think might be minor carpal tunnel in my right hand (minor discomfort in the fleshy part below the thumb and kind of in the thumb joint itself), but I can't say 100% it's from this, because I'm old and have been weight lifting for 30 years, so I have aches and pains everywhere (herniated disk, strained shoulder, crunchy elbow, permanently tight and sore forearm, etc.) that all predated HGH usage. I just can't remember if the thumb issue was before or after.

Part of the reason I started HGH (in addition to fat loss and muscle gain as well as anti-aging) was to see if it would help with some of these issues. My shoulder is much better so I have hope.

Funny, I have the same thumb issue on rHGH. At its worst, if I move it first thing in the morning without thinking, if feels like I’m dislocating it lol.

As for all the other old injuries. Check your HS-CRP next time you get bloodwork.

Each time I’ve gotten it to go down, I’ve had a dramatic reduction in pain from old injuries. Like night and day from my high of 3.0 a couple of years ago to my current 0.4. Wish I had discovered that sooner.

 

[BatmanVAR]

Funny, I have the same thumb issue on rHGH. At its worst, if I move it first thing in the morning without thinking, if feels like I’m dislocating it lol.

As for all the other old injuries. Check your HS-CRP next time you get bloodwork.

As each time I’ve gotten it to go down, I’ve had a dramatic reduction in pain from old injuries. Like night and day from my high of 3,0 a couple of years ago to my current 0.4. Wish I had discovered that sooner.

Ouch, my thumb isn't near that bad thankfully.

I'm getting blood work next week, and I just checked the request and funny enough HS-CRP is listed as part of the comprehensive panel I'm getting, and will be my first time getting this specific test (previous labs have been much more basic). Appreciate the recommendation.

Have you done something specifically to bring that number down? Or has it been a result of HGH?

 

[heady muscle]

I forgot about this thread. I am glad it is back in circulation.