Accutane permanent cure?

For you guys that were (or still are) at a high-ish dose for a while, does staying at the exact same dose eventually make all of the uncomfortable dryness sides go away? Does the body get used to a certain dose with time and adjust?
For me, the sides calmed down some from their peak after titrating up to my next dose each time, but the overall effect seemed to be dose dependent. Overall higher dose= more/more severe sides, but in my exp was not linear, if that makes sense. Like a 50% bump in dosage netted like ~15-20% more severe sides.

The only oddity for me was coming back down and not getting relief.
 
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