Any explanation as to why IGF isnt correlating to dosage of GH?

[Ateam2023]

If I recall correctly, I have come across this explanation a few times:

Essentially, you have serum IGF-1 levels circulating in your blood, and you have tissue-specific IGF-1 that is actively working within certain bodily tissues. It is the tissue IGF-1 that is responsible for things like muscle growth/repair, bone development, etc. The only one we are able accurately test for is serum IGF-1, so that is the number you'll see on blood tests, irrespective of your tissue IGF-1 levels. So, basically, a blood test is a relatively poor indicator of how effective or potent your rHGH is.

a gh serum test is a good way to determine "potency" of your hgh product, igf1 is just a number and a finicky one at that, but with a good serum test it stands to reason and often is the fact, you have good hgh, oh yeah and cts , gotta get that too, lol

 

[aljowa]

a gh serum test is a good way to determine "potency" of your hgh product, igf1 is just a number and a finicky one at that, but with a good serum test it stands to reason and often is the fact, you have good hgh, oh yeah and cts , gotta get that too, lol

Ah, yeah, I should have caveated my last sentence by specifying "IGF-1 blood test" instead of just "blood test," since that could technically indicate any blood test whatsoever. I assumed that since OP's post only mentioned IGF-1 testing that this would be implied, but still a good catch. Always better to be as specific as possible when communicating on the internet, because people can interpret things in the wildest ways, lol.

 

[songsofpyramids]

Baseline was 90 something (id have to pull it up). And yes, 40 (soon to be 41) F. The igf of 197 was after 3 months.

Are you on oral contraceptive? The hgh binds to it rather than your gh receptors if you are. I believe other hormonal contraceptives also cause this issue but it’s been awhile since I read into it. I’ll try and look it up, but TypeIIX has a thread discussing it here somewhere. I believe it can take 30-50% more hgh to achieve similar level of igf1 as men. My girl has had to take close to 4iu to get where I get on 2.4-2.8iu. She seemed to get more out of ghrh + ghrp with than I ever did even with her bc. If not that cutting calories really hard, prolonged inflammatory states, and other stuff like illness can absolutely lower it. I think women respond more poorly to hgh on average and require more even with short stature children if I recall right.

 

[Jackedjack]

Ive never seen high igf1 numbers on myself, but my high or low range is completely calorie and protein dependant, more calorie than protein. Low calories = low igf

 

[cgahan]

Are you on oral contraceptive? The hgh binds to it rather than your gh receptors if you are. I believe other hormonal contraceptives also cause this issue but it’s been awhile since I read into it. I’ll try and look it up, but TypeIIX has a thread discussing it here somewhere. I believe it can take 30-50% more hgh to achieve similar level of igf1 as men. My girl has had to take close to 4iu to get where I get on 2.4-2.8iu. She seemed to get more out of ghrh + ghrp with than I ever did even with her bc. If not that cutting calories really hard, prolonged inflammatory states, and other stuff like illness can absolutely lower it. I think women respond more poorly to hgh on average and require more even with short stature children if I recall right.

No bc but could be a long term deficit that I've come out of within the past few months. That or stress. I have read the same, that we respond poorly on average. Older threads in the women's section had the recommendation of 1iu but I don't think that would do a thing for me. Have settled on the 3iu as a complement to the anavar cycle I'm running; may go back to 2iu after. Since it a long term game with gh, curious what (if any) impact it'll have. I think it's been about 5 months at this point.