ironwill1951
New Member
most guys that take dnp are just to lazy to diet and use a tredmill.
Follow along with the video below to see how to install our site as a web app on your home screen.
Note: This feature may not be available in some browsers.
most guys that take dnp are just to lazy to diet and use a tredmill.
Seems to be hard to find DNP. Maybe the raws are in short supply and it's all dried up. Watching this thread for any info though.
Well sir you don't really know how your body will react to 250 mg. Why would you take a drug that can quite literally kill you, you may think these people are joking but dnp with fucking kill you. Go buy some ketotifen take it with your clen, stay on your clen a little longer and fucking live your life. Don't die for 15lbs of fat loss
DNP is notorious for a reason, I think I know more people who took it and died than actually survived
CensoredBoardsSuck
CensoredBoardsSuck
Awesome Member
Thanks to @censorboardssuck for posting this over a year ago
It's the time of year when bodybuilders start looking for ways to shed body fat and the interest for many invariably turns to DNP. There are articles on the internet that suggest DNP can be used safely if you're smart about it. Nothing could be further from the truth. DNP is a poison that has lead to cataracts, renal failure and deaths due to hyperthermia. It has an extremely narrow therapeutic index, i.e. the dose of DNP required to induce weight loss is very close to its lethal dose. In addition, its effects are unpredictable. A dose that was well tolerated in a previous cycle might not be tolerated on the next. As the use of DNP continues to gain in popularity, the death rate will continue to climb. There is no safe dose of DNP.
The first two studies below note the dosage of DNP in which deaths have occurred. These dosages are the same dosages currently being advertised as safe and the ones most often used by bodybuilders.
-------------------------------------------------------------------------------------------------------------
According to the U.S. Department of Health and Human Services, deaths have occurred in people who ingested 3--46 mg of dinitrophenols per kg of body weight per day (3-46 mg/kg/day) for short periods or 1--4 mg/kg/day for long periods.
Reports of DNP poisoning related to weight loss appear to be becoming more common. McFee et al. (13) reported the death of a 22-year-old male 16 h after his last DNP dose, estimated at 600 mg/day over four days for weight loss.
Journal of Analytical Toxicology, Vol. 30, April 2006
Case Report
Two Deaths Attributed to the Use of 2,4-Dinitrophenol
Estuardo J. Miranda 1, lain M. Mclntyre 2, Dawn R. Parker 2, Ray D. Gary 2, and Barry K. Logan TM
We report the cases of two individuals, one in Tacoma, WA, and
the second in San Diego, CA, whose deaths were attributed to
ingestion of 2,4-dinitrophenol (2,4-DNP). 2,4-DNP has historically
been used as a herbicide and fungicide. By uncoupling
mitochondrial oxidative phosphorylation, the drug causes a
marked increase in fat metabolism that has led to its use to aid
weight loss. Both cases reported here involved its use for this
purpose. Features common to both cases included markedly
elevated body temperature, rapid pulse and respiration, yellow
coloring of the viscera at autopsy, history of use of weight loss or
body building supplements, and presence of a yellow powder at
the decedent's residence. Because of its acidic nature, the drug is
not detected in the basic drug fraction of most analytical protocols,
but it is recovered in the acid/neutral fraction of biological extracts
and can be measured by high-performance liquid chromatography
or gas chromatography-mass spectrometry. The concentration
of 2,4-DNP in the admission blood samples of the two deaths
reported here were 36.1 and 28 rag/L, respectively. Death in both
cases was attributed to 2,4-DNP toxicity. Review of information
available on the internet suggests that, although banned,
2,4-DNP is still illicitly promoted for weight loss.
Introduction
[In the paper below, McFee et al. reported the death of a 22-year-old male 16 h after his last DNP dose, estimated at 600 mg/day over four days.]
Vet Hum Toxicol. 2004 Oct;46(5):251-4.
Dying to be thin: a dinitrophenol related fatality.
McFee RB1, Caraccio TR, McGuigan MA, Reynolds SA, Bellanger P.
Abstract
2, 4-dinitrophenol (DNP) was originally used as an explosive and later introduced in the 1930's to stimulate metabolism and promote weight loss. It's also a component of pesticides still available globally. Concerns about hyperpyrexia lead to DNP being banned as a dietary aid in 1938. A 22-y-old male presented to the Emergency Department (ED) with a change in mental status 16 h after his last dose of DNP. On admission he was diaphoretic and febrile with an oral temperature of 102 F, but lucid and cooperative. He became agitated and delirious. Intravenous midazolam was initiated with mechanical cooling. Pancuronium was administered later and the patient was intubated. Over the next hour the patient became bradycardic, then asystolic, and despite resuscitative efforts, died. Advertisements claim DNP safe at the dose our patient ingested. It is widely available and with the potential to cause severe toxicity is an understudied public health concern.
Regulatory Toxicology and Pharmacology 48 (2007) 115–1
Dinitrophenol and obesity: An early twentieth-century regulatory dilemma
Eric Colman
Abstract
In the early 1930s, the industrial chemical dinitrophenol found widespread favor as a weight-loss drug, due principally to the work of Maurice Tainter, a clinical pharmacologist from Stanford University. Unfortunately the compound’s therapeutic index was razor thin and it was not until thousands of people suffered irreversible harm that mainstream physicians realized that dinitrophenol’s risks outweighed its benefits and abandoned its use. Yet, it took passage of the Food, Drug, and Cosmetic Act in 1938 before federal regulators had the ability to stop patent medicine men from selling dinitrophenol to Americans lured by the promise of a drug that would safely melt one’s fat away.
Cyril MacBryde, a physiologist from Washington University School of Medicine, reported ‘‘alarming functional changes’’ indicative of liver, heart, and muscle toxicity in his obese patients treated with small doses of dinitrophenol (MacBryde and Taussig, 1935).
But some physicians continued to believe that the drug was a reasonable therapeutic option for obese patients recalcitrant to dietary intervention when used in the properdose and under the care of a knowledgeable physician. Even this position, however, became untenable when young women taking therapeutic doses of dinitrophenol under the supervision of physicians started going blind (Horner et al., 1935). If the estimate of one San Francisco ophthalmologist is accurate, during a two and a half year span, as many as 2500 Americans may have lost their sight due to what became known as ‘‘dinitrophenol cataracts’’ (Horner, 1936).
Australas J Dermatol. 2014 Nov 4. doi: 10.1111/ajd.12237. [Epub ahead of print]
Cutaneous drug toxicity from 2,4-dinitrophenol (DNP): Case report and histological description.
Le P1, Wood B, Kumarasinghe SP.
Abstract
The use of 2,4-dinitrophenol (DNP) has regained popularity as a weight loss aid in the last two decades due to increased marketing to bodybuilders and the increasing availability of this banned substance via the Internet. 2,4-DNP is a drug of narrow therapeutic index and toxicity results in hyperthermia, diaphoresis, tachycardia, tachypnoea and possible cardiac arrest and death. Skin toxicity from 2,4-DNP has not been reported since the 1930s. We report a case of a 21-year-old bodybuilding enthusiast who presented with a toxic exanthem after taking 2,4-DNP, and describe the first skin biopsy findings in a case of 2,4-DNP toxicity.
Apr 1, 2015 ReportBookmarkLike+ QuoteReply
flenser, xupc, dredd09 and 12 others like this.
Sent from my iPhone using Tapatalk
There is ALOT of unwanted attention on DNP, that's why it's become a pain in the ass to source.
I will warn everyone of using any "new" sources for this compound - you don't want some punk ass kid who's been capping in his kitchen for a week to be giving you this stuff. Seriously.
The dose makes the poison and there has only been 1 case study that I'm aware of showing death at 300mg. None whatsoever at 250mg.
And fucking LOL at you recommending a long run of clen as a safe alternative to a low dose of DNP. Just stop. Please.
DNP is notorious for attracting moron dieters with a "more is better" attitude, yes.
If you genuinely know more people who have died than survived on DNP, then I conclude that your circle of friends are morons. I suggest finding smartedr individuals to associate with.
Oh Roger, why not just link the actual thread so people can see the FULL picture hmm
Here we go: Think DNP Can Be Used Safely? Think Again
thanks for posting that long ass thread anyway. I decided not to cycle that poison. what i dont like hearing about dnp besides the harsh side effects is that it makes u crave carbs like it is pussy and u end up binging on foods , resulting less fat loss.Didn't know how so I just copied and post and gave credit to censorboardsucks.
Thanks for taking care of the link
Sent from my iPhone using Tapatalk
I find it funny most people who make comments about dnp use....HAVE NEVER USED DNP!
If I need to change out a blown headgasket on 62 impala, I'm not going to ask someone who never seen a 62 impala, or worst, dosent know what a head gasket is...
Yeah maybe because those who took the dnp have died and can't give you advice because they are dead as hellI find it funny most people who make comments about dnp use....HAVE NEVER USED DNP!
If I need to change out a blown headgasket on 62 impala, I'm not going to ask someone who never seen a 62 impala, or worst, dosent know what a head gasket is...
I find it funny most people who make comments about dnp use....HAVE NEVER USED DNP!
If I need to change out a blown headgasket on 62 impala, I'm not going to ask someone who never seen a 62 impala, or worst, dosent know what a head gasket is...
No one said it was better. In fact, the original post talks exactly about having done that first. But you didn't want to read the whole thread did you?explain to me why dnp which is a short term fix is better than learning a proper diet and cardio which is a lifetime fix ?
Did I ever say that?explain to me why dnp which is a short term fix is better than learning a proper diet and cardio which is a lifetime fix ?
Yeah maybe because those who took the dnp have died and can't give you advice because they are dead as hell
explain to me why dnp which is a short term fix is better than learning a proper diet and cardio which is a lifetime fix ?
Not that I'm suggesting DNP is the solution, but there is a very good reason why the industry is obsessed with pharmaceutical treatment, mitochondrial uncouplers included. Diet + cardio has failed.
Might want to check the latest obesity statistics man - good old fashioned diet + cardio has been a MASSIVE failure when it comes to long term, permanent change
Not that I'm suggesting DNP is the solution, but there is a very good reason why the industry is obsessed with pharmaceutical treatment, mitochondrial uncouplers included. Diet + cardio has failed.
No one said it was better. In fact, the original post talks exactly about having done that first. But you didn't want to read the whole thread did you?
Next step is comprehension.yes I read the whole thing smart ass.
I hope you were kidding, obesity stats are high because people don't do a proper diet and cardio. damn man if you burn more calories than you take in you will lose weight that is a simple fact.. and to believe any different is just plain foolish. good old fashion diet and cardio has never and never will be a failure.
