Any thoughts on myostatin inhibition?

[Y2JVD]

Wanted to know what anyones thoughts on gene doping and myostatin inhibition which in short is a form of gene doping where animals such as cattle have myostatin inhibited in their gene allowing for massive muscle mass with very little body fat. There have been cases of humans having their myostatin gene inhibited which resulted in this:

 

[Malik Agar]

Only a matter of time IMO...

From wiki:

Stamulumab (MYO-029[1]) is an experimental myostatin inhibiting drug developed by Wyeth Pharmaceuticals for the treatment of muscular dystrophy (MD). Stamulumab was formulated and tested by Wyeth in Collegeville, Pennsylvania.[2] Myostatin is a protein that inhibits the growth of muscle tissue, stamulumab is a recombinant human antibody designed to bind to and inhibit the activity of myostatin.[3]

Wyeth undertook a Phase 1 and 2 clinical trial in 2005 and 2006 of stamulumab. The multiple ascending dose trial (36 patients per cohort) contained some measures of efficacy. The trial's participants included people afflicted with Facioscapulohumeral muscular dystrophy, Becker's muscular dystrophy, and Limb-girdle muscular dystrophy. Through 2007 Wyeth had been analyzing the results but the hoped-for news and/or a publication in 2007 did not occur.[2][5][6] In January 24, 2008, Wyeth announced that the study had been accepted by a peer-reviewed journal and publication was expected "in the next few months".[7] The publication appeared in Annals of Neurology in May 2008. [8]

On 11 March 2008 it was announced that Wyeth would not develop the drug further for MD, but would continue to explore myostatin inhibition along with other strategies.[9]

Stamulumab is a G1 immunoglobulin antibody which binds to myostatin and prevents it from binding to its target site, thus inhibiting the growth-limiting action of myostatin on muscle tissue. Research completed in 2002 found that Stamulumab might one day prove to be an effective treatment for Duchenne muscular dystrophy[4]

 

[Michael Scally MD]

IMO, SARM/AAS will be passed over for other steps in muscle anabolism that will not disrupt the HPTA, NOT cause AIH.

https://thinksteroids.com/community/threads/134301198

https://thinksteroids.com/community/threads/134323830

https://thinksteroids.com/community/threads/134310283

 

[skywalk]

i think I read somewhere that creatine works as a myostatin inhibitor....to a certain point. as does clen. but the myostatin inhibitors you guys are talking about are on a whole different level. I hope they come out with a safe, marketable, commercially available statin. i'd be all over that! lol

 

[Y2JVD]

Yeah they have supps with the seaweed shit that supposed to inhibit myostatin but real myostatin inhibition is what that cattle and kid have. Creatine has myostatin inhibiting factors but they lose efficacy after two months on them and then you have to stop and wait for another two months and so on and

 

[Malik Agar]

Actually, that kid in the pic above isn't one of the myostatin kids. That's Richard Sandrak, whose father (now in prison) most likely started him on gear as an infant.

The two I know about are Liam Hoekstra:

and the German superbaby:

 

[Y2JVD]

Yeah i was trying to get another pic up of the other kid. Theres another kid in italy that supposedly has myostatin inhibition and hes been breaking world records but again that might be just another kid on juice.

 

[Y2JVD]

supposedly this kid