Anyone ran high dose anadrol

[Jestopherson]

Oh 150 definitely does work. But not if you’ve been on cycle over 12 weeks I’ve seen changes off of 50 Balkan alone this is really just to see what happens. Basically I’m trying to relive my first cycle experience strength gains but I think that’s gone forever

How would suddenly adding an additional 1050mg of anabolics a week not have any effect when you've been on cycle for 12 weeks? That makes no sense dude. You're saying if you added 60mg of var, dbol, or even tren to your cycle you wouldn't notice it since you've been on for 12 weeks?

I always run my orals at the end of the cycle. That way you get a huge boost and finish strong

 

[Dead]

How would suddenly adding an additional 1050mg of anabolics a week not have any effect when you've been on cycle for 12 weeks? That makes no sense dude. You're saying if you added 60mg of var, dbol, or even tren to your cycle you wouldn't notice it since you've been on for 12 weeks?

I always run my orals at the end of the cycle. That way you get a huge boost and finish strong

I’ve never done it at the end before so but unaware

 

[jJjburton]

Oh 150 definitely does work. But not if you’ve been on cycle over 12 weeks I’ve seen changes off of 50 Balkan alone this is really just to see what happens. Basically I’m trying to relive my first cycle experience strength gains but I think that’s gone forever

I dont meant to pick on you.

You have said this everytime. You are trying to relive your first cycle.

Remmeber your epistane, dmz, other oral craziness. You said this same thing. You said thats all your going to run here on out. Then 3 weeks later freaked out about acne. You said you were done with orals here.

This outcome will be exact.

Why not just EMBRACE! It all. Say i am running 400 mg i dont give a fuck.

Fuck it i am running 1000 mg tren!

 

[Jestopherson]

I’ve never done it at the end before so but unaware

So if you're never done it then how can you say it won't do anything for you?

 

[Plate Smacker]

I will show a study... however it's NOT on trained individuals running other compounds like us.

"Indeed, with 50 and 100 mg/day of oxymetholone, total LBM increased by 3.3 ± 1.2 and 4.2 ± 2.4 kg, respectively. These effects are of a magnitude similar to that achieved with 125 and 300 mg of testosterone enanthate (2.9 ± 0.8 and 5.5 ± 0.7 kg, respectively"

The 100mg group only gained 0.9kg more than 50mg group.

Strength and other things were measured.
Toxicity values were measured.

Again, we are using other compounds and some high testosterone only. Results will differ.
The study has limitations, particularly very small sample size. Others are listed at end.

https://journals.physiology.org/doi/full/10.1152/ajpendo.00363.2002?rfr_dat=cr_pub++0pubmed&url_ver=Z39.88-2003&rfr_id=ori%3Arid%3Acrossref.org

The only way to find out for yourself is run 50mg for 4 weeks, then bump to 100mg and see if it blows 50mg out the water.

It can kill some people's appetite at higher dosage.

Personally, I have ran 100mg. I have ran 50mg. I prefer 50mg. These aren't as high as others have ran.
Even at 50mg for me, back pumps sometimes become unbearable. The trap shoulder tie in also gets painful when doing shoulders.

Even 40mg ED is enough for dramatic results.

 

[Type-IIx]

I will show a study... however it's NOT on trained individuals running other compounds like us.

"Indeed, with 50 and 100 mg/day of oxymetholone, total LBM increased by 3.3 ± 1.2 and 4.2 ± 2.4 kg, respectively. These effects are of a magnitude similar to that achieved with 125 and 300 mg of testosterone enanthate (2.9 ± 0.8 and 5.5 ± 0.7 kg, respectively"

The 100mg group only gained 0.9kg more than 50mg group.

Strength and other things were measured.
Toxicity values were measured.

Again, we are using other compounds and some high testosterone only. Results will differ.
The study has limitations, particularly very small sample size. Others are listed at end.

https://journals.physiology.org/doi/full/10.1152/ajpendo.00363.2002?rfr_dat=cr_pub++0pubmed&url_ver=Z39.88-2003&rfr_id=ori%3Arid%3Acrossref.org

The only way to find out for yourself is run 50mg for 4 weeks, then bump to 100mg and see if it blows 50mg out the water.

It can kill some people's appetite at higher dosage.

Personally, I have ran 100mg. I have ran 50mg. I prefer 50mg. These aren't as high as others have ran.
Even at 50mg for me, back pumps sometimes become unbearable. The trap shoulder tie in also gets painful when doing shoulders.

Even 40mg ED is enough for dramatic results.

A couple other studies you may be interested in:
- Dose-response (10, 20, 30 mg) by N excretion calorically controlled, in-patient study
Saarne, et al. (1965). Studies on the Nitrogen Balance in the Human during Long-term Treatment with Different Anabolic Agents under Strictly Standardized Conditions. Acta Medica Scandinavica, 177(2), 199–211. doi:10.1111/j.0954-6820.1965.tb01822.x

- Toxicity at 50 vs 100 vs 150 mg (grade 3/4 liver toxicity) and prevalence
Hengge UR, Stocks K, Faulkner S, Wiehler H, Lore
nz C, Jentzen W, Hengge D, Ringham G. Oxymetholone for the treatment of HIV-wasting: a double-blind, randomized, placebo-controlled phase III trial in eugonadal men and women. HIV Clin Trials. 2003 May-Jun;4(3):150-63. doi: 10.1310/hct.2003.4.3.002. PMID: 12815555.
Adrol was approved for 50 mg therapeutic use for HIV wasting after this trial.

 

[egonormical1010]

Yeah I lied it’s more like 400 I just wanted to see how it goes. All I know is my nose is bleeding when I blow it my head hurts and I’m seething fucking mad for no reason and not anything is making me feel happy. But that might be the npp npp makes me rage horribly so it may be that

I can promise you that you’re not “seething fucking mad for no reason”. THE REASON is that you’re fucking batshit crazy. You are literally the male version of an Instagram attention whore.

 

[Habib]

I've heard of some people running up to 300mg/day. Crazy shit, I will be looking to run a Adrol/Dbol combo at half the doses at some point for mad gains

 

[eery]

I've heard of some people running up to 300mg/day. Crazy shit, I will be looking to run a Adrol/Dbol combo at half the doses at some point for mad gains

Thats an awesome combo, i really like 20-30mg of each combined preworkout. Add 10mg cialis and your pumps are going to be mad.

 

[Rido]

Starter dose for people with anadrol is 2mg per kg of body weight.

Dosage Range is 1-5mg per kg of body weight

Normal plan is 1-2mg per kg of body weight for 3-6 month!!!(mind=blown)

 

[Type-IIx]

Starter dose for people with anadrol is 2mg per kg of body weight.

Dosage Range is 1-5mg per kg of body weight

Normal plan is 1-2mg per kg of body weight for 3-6 month!!!(mind=blown)

That doesn't scale for healthy adult use of oxymetholone (obviously). The dosage that was approved after clinical trials was 50mg daily for HIV wasting.

 

[Rido]

That doesn't scale for healthy adult use of oxymetholone (obviously). The dosage that was approved after clinical trials was 50mg daily for HIV wasting.

That dosage was for chemotherapy or cancer related anemia in the 60s....



They also show it on uptodate(Which healthcare professionals use)

 

[Type-IIx]

That dosage was for chemotherapy or cancer related anemia in the 60s....

View attachment 159072

They also show it on uptodate(Which healthcare professionals use)

Right: this does not scale for healthy adults. Do you suppose individuals with these forms of (aplastic, congential, hypoplastic) anemia (and myelofibrosis) are A) healthy, or B) of obese BMI comprised principally of skeletal muscle?

 

[Type-IIx]

You guys have to be careful interpreting data (clinical trials, research abstracts or full text). Physiological rationales for dosing depends on the subject population. For example, in adults rhGH dosing is logically based on body mass (m^2); then at some point the WHO put out an advisory that dramatically curtailed doses based on tolerability. In children, doses are often like 0.1IU/kg 3x weekly (though an advisory was put out to get away from using IU in GH research, likely because it was readily comprehensible yet dangerous for this very reason for the average guy). Anecdote: A guy that posts here says/believes strongly that he developed congestive heart failure because he used doses from a study in children based on mg/kg. DO NOT DO THIS.

 

[GuerillaPete]

You guys have to be careful interpreting data (clinical trials, research abstracts or full text). Physiological rationales for dosing depends on the subject population. For example, in adults rhGH dosing is logically based on body mass (m^2); then at some point the WHO put out an advisory that dramatically curtailed doses based on tolerability. In children, doses are often like 0.1IU/kg 3x weekly (though an advisory was put out to get away from using IU in GH research, likely because it was readily comprehensible yet dangerous for this very reason for the average guy). Anecdote: A guy that posts here says/believes strongly that he developed congestive heart failure because he used doses from a study in children based on mg/kg. DO NOT DO THIS.

Could a healthy adult using the best protocol to minimize health risk and all supplements/medication to combat insulin resistance , timing meals accordingly get away without major side effects if using 3-4 iu hgh for hrt? Talking about the average guy not outliners?in your opinion of course not asking like medical advice just for conversation sake ?

 

[Villain]

You guys have to be careful interpreting data (clinical trials, research abstracts or full text). Physiological rationales for dosing depends on the subject population. For example, in adults rhGH dosing is logically based on body mass (m^2); then at some point the WHO put out an advisory that dramatically curtailed doses based on tolerability. In children, doses are often like 0.1IU/kg 3x weekly (though an advisory was put out to get away from using IU in GH research, likely because it was readily comprehensible yet dangerous for this very reason for the average guy). Anecdote: A guy that posts here says/believes strongly that he developed congestive heart failure because he used doses from a study in children based on mg/kg. DO NOT DO THIS.

Have you read Michael Scally’s article on Anadrol for obesity? Wondering what your thoughts are on it: Obesity & AAS

Also:
Post in thread '26 percent body fat'
26 percent body fat

 

[Rido]

Right: this does not scale for healthy adults. Do you suppose individuals with these forms of (aplastic, congential, hypoplastic) anemia (and myelofibrosis) are A) healthy, or B) of obese BMI comprised principally of skeletal muscle?

it was mostly done on cachetic patients. my point wasnt to target that dose, it was more of the safety. Some people will do dose adjusted body weight which is alot more accurate.

I see where you are coming from and I completely agree with you. It was just more food for thought type of thing.

My other point is that you said that the dosing I mentioned was for HIV patients, when the dosing was actually made for anemic patients. You also said it was approved for HIV wasting, when it is actually off label

I dont think people would probably need to ever really surpass 150mg. I know I definitely wouldnt(I am still fresher than most),


but it would be safe to assume with 5mg/kg/bw. for a lady with cancer at 45mg/kg/bw. would easily be around 225mg a day.

You also have to take into consideration that these cancer patients are typically hypovolemic, poor PO intake. take multiple hepatotoxic medication.

It was just food for thought that we are in the lower limits. we all know there are already studies that show diminishing returns between 50mg vs 100mg.

 

[Type-IIx]

it was mostly done on cachetic patients. my point wasnt to target that dose, it was more of the safety. Some people will do dose adjusted body weight which is alot more accurate.

I see where you are coming from and I completely agree with you. It was just more food for thought type of thing.

My other point is that you said that the dosing I mentioned was for HIV patients, when the dosing was actually made for anemic patients. You also said it was approved for HIV wasting, when it is actually off label

I dont think people would probably need to ever really surpass 150mg. I know I definitely wouldnt(I am still fresher than most),


but it would be safe to assume with 5mg/kg/bw. for a lady with cancer at 45mg/kg/bw. would easily be around 225mg a day.

You also have to take into consideration that these cancer patients are typically hypovolemic, poor PO intake. take multiple hepatotoxic medication.

It was just food for thought that we are in the lower limits. we all know there are already studies that show diminishing returns between 50mg vs 100mg.

No doctor is prescribing a little old lady with cancer 225 mg oxymetholone daily.

After Hengge my understanding is 50 mg daily was approved for HIV wasting.

I don't think 50 - 150 mg is absurd, just that it has a high prevalence of stage 3/4 liver toxicity. Specifically, 27% (n=8) of the 100 mg group vs. 35% (n=11) of the 150 mg group saw ALT, AST, or GGT elevated by >5-fold (in HIV wasting patients).

 

[Type-IIx]

Have you read Michael Scally’s article on Anadrol for obesity? Wondering what your thoughts are on it: Obesity & AAS

Also:
Post in thread '26 percent body fat'
26 percent body fat

Nothing crazy. What I like about it is we get to call:
Week 1 - 4: 50mg Adrol
Week 5 - 8: 100mg Adrol
Week 9 - 12: 150mg Adrol

The Scally protocol.

It's a lot better than the Abdulredah protocol from my clen studies (some Iraqi doctor used this protocol, totally didn't provide the clen, in a "cross-sectional" [non-interventional] study).

 

[Rido]

No doctor is prescribing a little old lady with cancer 225 mg oxymetholone daily.

After Hengge my understanding is 50 mg daily was approved for HIV wasting.

I don't think 50 - 150 mg is absurd, just that it has a high prevalence of stage 3/4 liver toxicity. Specifically, 27% (n=8) of the 100 mg group vs. 35% (n=11) of the 150 mg group saw ALT, AST, or GGT elevated by >5-fold (in HIV wasting patients).

They arent gonna use anadrol for cancer treatment anymore anyway. Better options now

But you are right, it seems like there was no true benefit of 50mg BID vs 50md TID. difference was minor increase of mild hepatotoxicity. It may be worth noting that the placebo group was about the same as the BID group.

It is also worth noting that I think about 25% of them were on diflucan which is hepatotoxic.