I had low e2 symptoms despite my e2 was fine on bloodwork. It dropped my libido, made all my joints hurt which i eventually made me fck up again my already damaged shoulder and also gave me cramps and muscle spasm. Every time i was going to sit or lift up from a standing position my lower quads were doing spasm, you could see the muscle moving like it was alive. It happened with my biceps, forearms, triceps and sometimes lats too.
Aesthetically 500mg didn't do much, tren at 1/3 was 10 times better.. Primo is way, way better too for me. I just fell for the hype, seeing everyone saying it's the best "feel good" compound, high libido etc but it was jackshit to me.