The Bruiser
New Member
I read in some post that Arimidex limits your gains during a cycle. Anybody know anything about this?
MESO-Rx
Anabolic Steroids
Arimidex limits gains while juicen'?
- Thread starter The Bruiser
- Start date
einstein1905
New Member
Some estrogen is conducive to an anabolic environment. Arimidex inhibits the conversion of test to estrogen. However, you can't think of it as an all or none issue. You have to consider how much test you're taking and how much arimidex you're taking. Arimidex doesn't prevent every single aromatase reaction...it simply reduces the number of successful test-->estrogen conversions. Some estrogen is good...too much is terrible. When you're running test, you should be utilizing anti-e's, and not just a SERM, such as nolvadex.The Bruiser said:
Grizzly
New Member
what he said.
Southernjuice
New Member
I agree!einstein1905 said:
einstein1905
New Member
The tabs were probably higher dosed.....0.25mg.brasco said:
How much was just test (omna)?
Some bloat is good. There is a reason all the big pros are bloated during the offseason. However, too much bloat is almost guaranteed hypertension and should be carefully monitored. You also have to take into account how much bf you have. A person with more bf is going to require more anti e, given they're taking the same amount of test. It's really very individualized.
Einstein,
What's the basis for this statement:
"When you're running test, you should be utilizing anti-e's, and not just a SERM, such as nolvadex."
Just curious.
MaxRep
What's the basis for this statement:
"When you're running test, you should be utilizing anti-e's, and not just a SERM, such as nolvadex."
Just curious.
MaxRep
einstein1905
New Member
MaxRep said:
The hypertension caused by crazy high estrogen levels aren't worth the risk IMO. Nolva will block a % of estrogen receptors, but the conversion of test--->estrogen continues. Estrogen acts indirectly on the renin/angiotensin system to increase aldosterone levels and retain water. Estrogen also indirectly acts on antidiuretic hormone to retain water. Also, now this part is just theory, estrogen in the body unbound to its recptors signals the body that there is a very high plasma estrogen level and will further increase SHBG expression, which will bind your free testosterone, and test derivatives, I believe too. An anti-aromatase will greatly reduce the conversion of test to estrogen. therefore, the test will either bind receptors or be naturally degraded. You'll still have a very high plasma test level, signaling upregulation of SHBG, but you won't extend that signal by the high estrogen levels too.
Also, you have Xmg/mL of serum test...some of it is imediately occupied by aromatase during enzymatic conversion to estrogen....some of it is bound by SHBG (increasingly so, as serum test levels remain elevated over time).....some of it binds androgen receptors. I'm of the opinion that I want as much of the test doing the latter and very little doing anything else.
The hypertension caused by estrogens are obviously not something we want. Increased bp stresses the heart....then we compound that with extremely strenuous training, beta agonists (in some cases), etc. Of all the muscles we focus on, I think the heart is the most important and the most neglected.
Einstein,
Most of what you're saying makes sense although as you point out, some of it is still theory.
It is important to remember that when using an aromatase inhibitor, the goal is not to reduce estrogen to ultra-low levels. Which with arimidex and other AI's is not that hard to do. For example, many people are unaware that estrogen is critical to male fertility, which is why the AI's should not be a part of PCT. Not to mention estrogens role in reducing cholesterol, increasing glucose utilization, and increasing GH/IGF-1 levels.
MaxRep
Most of what you're saying makes sense although as you point out, some of it is still theory.
It is important to remember that when using an aromatase inhibitor, the goal is not to reduce estrogen to ultra-low levels. Which with arimidex and other AI's is not that hard to do. For example, many people are unaware that estrogen is critical to male fertility, which is why the AI's should not be a part of PCT. Not to mention estrogens role in reducing cholesterol, increasing glucose utilization, and increasing GH/IGF-1 levels.
MaxRep
einstein1905
New Member
MaxRep said:
Very well put. On the flip side, people also have to realize that taking moderate doses of AI's won't necessarily inhibit test to estrogen conversion to any where below physiological norms....Ideally, you'd want higher than normal estrogen levels during a cycle, but not so much where hypertension becomes an issue or where estrogen levels are affecting free test levels by any of the mechanisms above. If someone could dig up some data showing consistent and reproducible dose-dependent reduction is estrogen vs dose of anastrazole, it would be a godsend. Right now, we're only guessing when it comes to the levels of test we take in vs. the amount of ldex/day.
The point is....."AI's will inhibit gains" isn't necesarily true nor is it completely wrong.
einstein1905
New Member
Dart said:AWESOME, That settles that then.
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Well, I can't go wrong with a leg on either side of the fence Like a damn tabloid reporter....quotes me out of context
The Bruiser
New Member
So in conclusion, Arimidex should be taken while on test, but the dosage is unknown? How the hell do you determine how much to take?
einstein1905
New Member
0.25mg ED is used often for anything around 500-750mg/wk + 10mg ED of nolva. That's my personal guidelineThe Bruiser said:
Simple, but this is THE LAST TIME I WILL SHARE THIS INFO.The Bruiser said:
Just divide the proactive molecule of the substance multiplied by the dense capacity of your striation. Once you have this number, do six situps and then add the total number of pain amps per pressure synethisis.
Bro it's so easy, you just have to look this shit up in Google really...
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einstein1905
New Member
Dart said:Simple, but this is THE LAST TIME I WILL SHARE THIS INFO.
Just divide the proactive molecule of the substance multiplied by the dense capacity of your striation. Once you have this number, do six situps and then add the total number of pain amps per pressure synethisis.
Bro it's so easy, you just have to look this shit up in Google really...
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I came up with (-12). Now what?
big rob
New Member
With a total of -12 you must go to the general discussion area and play with some titties ASAP..............................
