90%, that's letro bro, I've been doing some research on exemestane and the actual percentages of how much it lowers estrogen are all over the place. And these are based on 25mg/ed. I think it might be around 60%. So far I think it's good stuff. Evidently I'm sensitive to gyno. Nolvadex has always done the job. It makes me shed water weight and definitely up's my definition at the cost of a little size (prob water anyway). In fact I've never even tried an AI like a-dex or letro. Never felt the need. But asin has some properties to it I find interesting and so I'm using it with nolva to see if I can reverse or deactivate the problem receptors. Here's some wiki info:
Exemestane is an irreversible, steroidal aromatase inactivator, structurally related to the natural substrate
androstenedione. It acts as a false substrate for the aromatase enzyme, and is processed to an intermediate that binds irreversibly to the active site of the enzyme causing its inactivation, an effect also known as "
suicide inhibition." By being structurally similar to enzyme targets, Exemestane permanently binds to the enzymes, preventing them from converting androgen into estrogen.
The estrogen suppression rate for exemestane varies from 35% for
estradiol (E2) to 70% for
estrone (E1).
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